MODAFINIL

作品数:21被引量:13H指数:2
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相关领域:医药卫生更多>>
相关作者:肖艳丽董志周岐新廖红傅洁民更多>>
相关机构:重庆医药工业研究院重庆医科大学华中科技大学沈阳军区总医院更多>>
相关期刊:《Acta Pharmacologica Sinica》《Journal of Pharmacy and Pharmacology》《Open Journal of Psychiatry》《医药简讯(广州)》更多>>
相关基金:国家自然科学基金更多>>
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Thermodynamic Resolution of Pharmaceutical Precursor Modafinil Acid on the Basis of Chiral-at-Metal Strategy
《Chinese Journal of Chemistry》2021年第6期1483-1490,共8页Man-Li Cao Jun-Ling Zhu Zhong-Lan Zhi Bao-Hui Ye Su-Yang Yao Xiu-Lian Zhang 
the National Natural Science Foundation of China(No.21971266);the Guangdong Provincial Key Platforms and Major Scientific Research Projects of Universities(No.2019KQNCX101);the Pan Deng Project of Guangdong Province(No.pdjh2020b0431);We also thank Dr.Long Jiang from Sun Yat-sen University instrumental analysis and research center.
Chiral-at-metal strategy was developed to resolve the essential sulfoxide pharmaceutical intermediates R-modafinil acid and its ana-logues with high yields and ee values.The efficient resolution process was achieved b...
关键词:Chiral resolution Chiral-at-metal complexes Modafinil acid Chiral pharmaceutical Ir(III)complexes 
Identification of adrafinil and its main metabolite modafinil in human hair.Self-administration study and interpretation of an authentic case被引量:1
《Forensic Sciences Research》2020年第4期322-326,共5页Alice Ameline Laurie Gheddar Jean-Sébastien Raul Pascal Kintz 
For several years,the misuse of stimulant substances is increasingly observed both in the field of sport,to improve the functions of the body and therefore to be more performant,and also by non-athletes to make life m...
关键词:Forensic sciences forensic toxicology adrafinil MODAFINIL human hair UPLC-MS/MS STIMULANTS 
The Effects of Modafinil in People with a Diagnosis of Schizophrenia
《Open Journal of Psychiatry》2018年第1期91-96,共6页Christopher A. Griffiths Alessandra Girardi 
This review seeks to describe the use and effects of the drug modafinil. Specifically, it presents the research of the impact of modafinil for people with diagnosis and experience of schizophrenia. Recent reviews have...
关键词:MODAFINIL COGNITIVE Enhancement SCHIZOPHRENIA Quality of LIFE Wellbeing RECOVERY 
Modafinil for prolonged disorder of consciousness
《中华物理医学与康复杂志》2017年第10期731-731,共1页
关键词:莫达非尼 中枢神经系统 多发性硬化 兴奋剂 患者 
Hypersexuality after Modafinil Treatment: A Case Report
《Journal of Pharmacy and Pharmacology》2015年第1期39-41,共3页Suheyla Dogan Bulut Rlza Gokger Tulaci Semanur Turkoglu Serdar Bulut Sibel Orsel 
Modafinil is employed for the treatment of narcolepsy and other sleep disorders like idiopathic hypersornnia. Modafinil is involved in the modulation of orexin, a hypothalamic neuropeptide that regulates wakefulness. ...
关键词:MODAFINIL HYPERSEXUALITY idiopathic hypersomnia. 
Population pharmacokinetics of modafinil acid and estimation of the metabolic conversion of modafinil into modafinil acid in 5 major ethnic groups of China被引量:3
《Acta Pharmacologica Sinica》2012年第11期1401-1408,共8页Ke-hua WU Tao GUO Chen-hui DENG Zheng GUAN Liang LI Tian-yan ZHOU Wei LU 
Aim: To describe the population pharmacokinetic profile of modafinil acid and to compare the extent of metabolism of modafinil into modafinil acid in 5 major ethnic groups (Han, Mongolian, Korean, Uygur, and Hui) o...
关键词:MODAFINIL modafinil acid ETHNICITY ethnic group in China population pharmacokinetics NONMEM drug metabolism ESTERASE amidaset 
Ventricular Tachycardia during Treatment with Modafinil for Narcolepsy: A Case Report
《International Journal of Clinical Medicine》2012年第6期513-517,共5页Heleen Binnenmars Herman H. D. Idzerda Hanno L. Tan Gerard C. M. Linssen 
Pharmacological treatment of narcolepsy is complex. We reported a case of recurrent episodes of polymorphic ventricular tachycardia attributed to the use of modafinil, a recently approved wake-promoting agent for narc...
关键词:MODAFINIL NARCOLEPSY VENTRICULAR TACHYCARDIA 
Pharmacokinetics of modafinil tablets in Chinese Mongolian, Uygur,and Hui healthy volunteers被引量:1
《中国新药与临床杂志》2010年第11期822-826,共5页ZHAO Long-shan GUO Tao XIA Dong-ya 
Project supported by the Entire Armed Forces 15 Medicine Health Science and Technology Attack Topic (06G023)
Influence of sex on the pharmacokinetics of modafinil in healthy Chinese volunteers
《Journal of Chinese Pharmaceutical Sciences》2010年第6期477-481,共5页赵龙山 高硕 郭涛 夏东亚 
Entire Armed Forces 15 Medicine Health Science and Technology Attack Topic(Grant No.06G023)
The purpose of this study was to determine the pharmacokinetic characteristics of modafinil and its metabolite modafinil acid in healthy subjects including Chinese Mongolian, Korean and Uyghur, and assess the influenc...
关键词:MODAFINIL SEX PHARMACOKINETICS 
modafinil
《中国处方药》2009年第3期18-18,共1页李天星 
Modafinil(莫达非尼)曾经被认为是一种十分安全有效的抗疲劳药物,它主要通过诱导大脑释放多巴胺积累发挥强大的兴奋作用。因它兴奋作用轻微,同时能使用者保持旺盛的精力且不影响睡眠,又无成瘾性,所以倍受人们的青睐。但美国医学...
关键词:抗疲劳药物 药物 治疗方法 医疗卫生行业 发展现状 
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