GLUCOLIPOTOXICITY

作品数：6被引量：50H指数：2
导出分析报告
相关领域：医药卫生更多>>
相关作者：肖建中更多>>
相关机构：清华大学更多>>
相关期刊：《World Journal of Gastroenterology》《Chinese Medical Journal》《Bone Research》《Food Science and Human Wellness》更多>>
相关基金：中国博士后科学基金国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-6
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Theaflavin-3,3'-digallate alleviates glucolipotoxicity-induced insulin secretion dysfunction in pancreaticβ-TC-6 cells and zebrafish via anti-ferroptotic mechanisms by activating SERCA2
《Food Science and Human Wellness》2025年第4期1498-1513,共16页Kaixi Wang Huanqing Zhu Jiaxin Kang Shuna Chen Puming He Youying Tu Bo Li 
supported by National Natural Science Foundation of China(32272303);Natural Science Foundation of Zhejiang Province,China(LY21C200010)。
Theaflavins from black tea effectively improve insulin secretion in obesity and diabetes,but the molecular mechanisms are unclear.Here,the palmitic acid(PA)-induced pancreaticβ-TC-6 cells and high fat-/high glucose-i...
关键词：Theaflavin-3 3'-digallate Pancreaticβ-cells Ferroptosis Endoplasmic reticulum stress Sarcoplasmic/endoplasmic reticulum calcium ATPase 2 
Targeting ferroptosis suppresses osteocyte glucolipotoxicity and alleviates diabetic osteoporosis被引量：38
《Bone Research》2022年第3期509-523,共15页Yiqi Yang Yixuan Lin Minqi Wang Kai Yuan Qishan Wang Pei Mu Jingke Du Zhifeng Yu Shengbing Yang Kai Huang Yugang Wang Hanjun Li Tingting Tang 
supported by National Natural Science Foundation of China(NSFC)grants 92068205,81802679,and 82002328;supported by China Postdoctoral Science Foundation grants 2018M632136 and 2019T120348。
Diabetic osteoporosis(DOP) is the leading complication continuously threatening the bone health of patients with diabetes. A key pathogenic factor in DOP is loss of osteocyte viability. However, the mechanism of osteo...
关键词：PEROXIDATION OSTEOPOROSIS DIABETIC 
Muscadine or amla extracts standardized to ellagic acid content ameliorate glucolipotoxicity associatedβ-cell dysfunction via inhibition of IL-1βand improved insulin secretion
《Food Production, Processing and Nutrition》2020年第1期91-101,共11页Srikanth Earpina Karen McDonough Millicent Yeboah-Awudzi Kristina J.Cook Sita Aggarwal Jack N.Losso 
Glucolipotocixity induces IL-1βsecretion which impairs pancreaticβ-cell insulin secretion.Ellagic acid and urolithin A have strong anti-inflammatory effect on cells.Muscadine and amla are very good sources of ellagi...
关键词：Muscadine Amla Ellagic acid NIT-1 pancreaticβ-cells glucose Palmitic acid GLUCOLIPOTOXICITY IL-1Β Inflammation INFLAMMASOME Insulin secretion 
Role of RIP140 in Pioglitazone inhibiting glucolipotoxicity-induced injury in β cells
《China Medical Abstracts(Internal Medicine)》2017年第1期22-23,共2页薛君力 
Objective To investigate the protective effect of Pioglitazone,a kind of peroxisome proliferators activated receptor(PPAR-γ)agonist,on the glucolipotoxicity-induced injury ofβcells,and also evaluate the role of rece...
关键词：RIP MIN cells Role of RIP140 in Pioglitazone inhibiting glucolipotoxicity-induced injury in 
Gastrointestinal metabolic surgery for the treatment of type 2 diabetes mellitus被引量：10
《World Journal of Gastroenterology》2014年第39期14315-14328,共14页Eng-Hong Pok Wei-Jei Lee 
Medical therapy for type 2 diabetes mellitus is ineffective in the long term due to the progressive nature of the disease, which requires increasing medication doses and polypharmacy. Conversely, bariatric surgery has...
关键词：Metabolic surgery Gastrointestinal surgery Type-2 diabetes mellitus GLUCOLIPOTOXICITY EFFICACY Prognostic factor 
Tissue inhibitor of metalloproteinase-1 counteracts glucolipotoxicity in the pancreatic β-cell line INS-1被引量：2
《Chinese Medical Journal》2011年第2期258-261,共4页JIANG Hong-wei ZHU Han-yu WANG Jian-zhong FU Bo LU Yang HONG Quan XIE Yuan-sheng CHEN Xiang-mei 
Background Glucolipotoxicity might play an important role in the β cell decompensation stage during the development of obesity-associated type 2 diabetes.Tissue inhibitor of metalloproteinase-1 （TIMP-1） inhibits ma...
关键词：GLUCOLIPOTOXICITY tissue inhibitor of metalloproteinase-1 pancreatic β-cell line INS-1 
全选清除导出
共1页<1>
检索报告 对象比较 聚类工具 使用帮助 返回顶部