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This work was supported by the National Key Research and Development Program of China(Nos.2020YFA0908500 and 2018YFA0901600);the National Natural Science Foundation of China(Nos.22275046,22161142015,22075065,22001054,and 22201058);the Hangzhou Leading Innovation and Entrepreneurship Team Project(No.TD2022001);the startup fund from Hangzhou Normal University(No.2019QDL026).
Live bacteria-based drug delivery systems have been raised as promising tools for enhancing drug delivery into tumors due to their active tumor targeting and easy surface modifiability.In this work,a“Trojan nanobacte...
supported by the National Science and Technology Major Project(Nos.2018ZX09J18101 and 2019ZX09J19103);the National Natural Science Foundation of China(No.81703048).
Gene therapy employs exogenous nucleic acids to treat genetic diseases and disorders.The insufficient cytosolic delivery of genetic materials remains a major hurdle for effective gene therapy.To address this challenge...
Hair loss due to medical conditions,such as alopecia,male pattern baldness,and cancer chemotherapy treatment,has been a comm onproblem for many in dividuals.Cyclospori n A(CsA),a fungal metabolite,has been reported to...
This work was financially supported from National Natural Science Foundations of China (Nos. 51331006 and 51271044).
Carbon-coated SiC@C nanocapsules (NCs) with a hexagonal platelet-like morphology were fabricated by a simple direct current (DC) arc-discharge plasma method. The SiC@C NCs were monocrystalline, 120-150 nm in size,...
An alternative model to the well-established paradigm of the externally switchable drug delivery systems is herein proposed. In contrast to the on--off archetype, here the amount of released drug is pre-set by the app...
Diabetes is a serious public health problem affecting 422 million people worldwide. Traditional diabetes management often requires multiple daily insulin injections, associated with pain and inadequate glycemia contro...
We report the preparation and encapsulation properties of stimuli-responsive nanocapsules, self-assembled by the noncovalent interactions of cyclodextrin- appended polymers (host) and complementary ferrocene or azob...
This work is supported by the National Natural Science Foundation of China (NSFC, Nos. 91127045, 51390483, 51473319, 51303025, 81401439 and 51343007), YG2012MS38 and China Postdoctoral Science Foundation (No. 2014M551399).
Protein therap34 wherein therapeutic proteins are delivered to treat disorders, is considered the safest and most direct approach for treating diseases. However, its applications are highly limited by the paucity of e...