NANOCAPSULE

作品数：28被引量：78H指数：4
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A tetrahedral framework nucleic acid based multifunctional nanocapsule for tumor prophylactic mRNA vaccination被引量：2
《Chinese Chemical Letters》2023年第7期169-175,共7页Yuhao Liu Songhang Li Shiyu Lin Sirong Shi Taoran Tian Bowen Zhang Tao Zhang Yunfeng Lin 
supported by National Key R&D Program of China (No. 2019YFA0110600);National Natural Science Foundation of China (No. 81970916);Sichuan Province Youth Science and Technology Innovation Team (No. 2022JDTD0021);Research Funding from West China School/Hospital of Stomatology Sichuan University (No. RCDWJS2021-20);China Postdoctoral Science Foundation (No. 2022TQ0381)。
Synthetic antigen-encoding mRNA plays an increasingly significant role in tumor vaccine technology owing to its antigen-specific immune-activation. However, its immune efficacy is challenged by inferior delivery effic...
关键词：Tetrahedral framework nucleic acid(tFNA) RNA nanovaccine Cytosine-phosphate-guanine(CpG)motifs Murineβ-defensin 2(mDF2β) Tumor immunotherapy 
Trojan nanobacteria hybridized with prodrug nanocapsules for efficient combined tumor therapy
《Nano Research》2023年第7期9651-9662,共12页Mingsong Zang Yuancheng Ji Xiaoran Ding Zhengwei Xu Jinxing Hou Jianxin Sun Jiayun Xu Shuangjiang Yu Hongcheng Sun Tingting Wang Junqiu Liu 
This work was supported by the National Key Research and Development Program of China(Nos.2020YFA0908500 and 2018YFA0901600);the National Natural Science Foundation of China(Nos.22275046,22161142015,22075065,22001054,and 22201058);the Hangzhou Leading Innovation and Entrepreneurship Team Project(No.TD2022001);the startup fund from Hangzhou Normal University(No.2019QDL026).
Live bacteria-based drug delivery systems have been raised as promising tools for enhancing drug delivery into tumors due to their active tumor targeting and easy surface modifiability.In this work,a“Trojan nanobacte...
关键词：live bacteria hybrid covalent nanocapsule photothermal therapy chemodynamic therapy 
Protein nanocapsules based vectors for efficient gene transfection
《Nano Research》2022年第1期264-271,共8页Xuan Hu Song Wang Junjie Xu Yilong Yang Zhang Zhang Xiaolin Wang Xiaopeng Zhang Wei Chen 
supported by the National Science and Technology Major Project(Nos.2018ZX09J18101 and 2019ZX09J19103);the National Natural Science Foundation of China(No.81703048).
Gene therapy employs exogenous nucleic acids to treat genetic diseases and disorders.The insufficient cytosolic delivery of genetic materials remains a major hurdle for effective gene therapy.To address this challenge...
关键词：protein nanocapsule self-assembly gene transfection cytosolic delivery degradation 
Gas-blasting nanocapsules to accelerate carboplatin lysosome release and nucleus delivery for prostate cancer treatment被引量：1
《Asian Journal of Pharmaceutical Sciences》2021年第2期192-202,共11页Shunli Fu Shuang Liang Dandan Jiang Rui Yang Zipeng Zhang Lili Chang Xinke Zhang Yongjun Liu Na Zhang 
This work was supported by a grant from the National Natural Science Foundation of China(Nos.81773652 and 81974498);the Young Scholar Program of Shandong University(2017WLJH40).
To improve therapeutic effect and reduce severely side effects of carboplatin(CBP),the gas-generating nanocapsules were developed to accelerate CBP lysosome release and nucleus delivery.CBP/SB-NC was prepared by co-lo...
关键词：CARBOPLATIN NANOCAPSULE pH-responsive release Gas-blasting Prostate cancer 
Simultaneous and Spatial Quantification of Telomerase Activity and DNA Methylation in Living Cells by a Deformable Satellite Nanocapsule
《CCS Chemistry》2021年第4期1231-1244,共14页Shan Huang Cheng Ma Jiahao Lin Wenjing Wang Yizhu Xu Xingxin Wu Jian-Rong Zhang Jun-Jie Zhu 
The authors gratefully acknowledge the financial support from the National Natural Science Foundation of China(nos.21834004 and 21904063);the Natural Science Foundation of Jiangsu Province(no.BK20190279).
Telomerase plays an essential role in many biological processes.DNA methylation regulates the expression of many genes,including telomerase.Here,we propose a deformable satellite nanocapsule fluorescein isothiocyanate...
关键词：TELOMERASE DNA methylation simultaneous detection single-cell level the efficacy of anticancer drugs 
Evolution in the formation of graphene nanocapsules from coal tar pitch被引量：1
《International Journal of Coal Science & Technology》2020年第4期816-824,共9页D.M.Puente-Siller A.E.Garcia-Castillo J.A.Lopez-Corpus A.Perea-Garduno 
Altos Homos de Mexico,S.A.B.de C.V.:Funding for tests and analysis of synthesised materials.Consejo Nacional de Cienciay Tecnologia(CONACyT):Funding under“Proyecto FORDECYT273496”.
It has recently been reported that coal tar pitch(CTP)can be utilised as raw material for the production of graphene nanocapsules(GNCs)because it is formed by a great quantity of aromatic organic compounds(which promo...
关键词：Synthesis NANOCAPSULE GRAPHENE TAR AGGLOMERATION 
Preparation of pH-Responsive Doxorubicin Nanocapsules by Combining High-gravity Antisolvent Precipitation with In-situ Polymerization for Intracellular Anticancer Drug Delivery被引量：2
《Chemical Research in Chinese Universities》2020年第5期927-933,共7页LIU Jie CHEN Bo ZHANG Jianjun 
Supported by the National Natural Science Foundation of China(Nos.2147601&21622601);the National Key R&D Pro gram of China(No.2015CB932101).
Owing to the low pH value in tumor and cancer cells,drug delivery systems based on pH-responsive polymer nanocarriers have been extensively explored for anticancer chemotherapy.Herein,we developed a pH-responsive doxo...
关键词：PH-RESPONSIVE NANOCAPSULE In-situ polymerization High-gravity anti solvent precipitation Anticancer cheniotherapy 
Control of random self-assembly of pyrogallol[4]arene-based nanocapsule or framework被引量：1
《Chinese Chemical Letters》2020年第7期2023-2026,共4页Kongzhao Su Shunfu Du Wenjing Wang Daqiang Yuan 
the Strategic Priority Research Program of the Chinese Academy of Sciences(No.XDB20000000);the National Nature Science Foundation of China(No.51603206);the Nature Science Foundation of Fujian Province(No.2016J05056)。
The controlled self-assembly of discrete metal-organic nanocapsules(MONCs),and metal-organic frameworks(MOFs)based on the MONCs are achieved.Specifically,the solvothermal reaction of nickel nitrate hexahydrate and C-m...
关键词：Controlled assembly arene Metal-organic nanocapsule Metal-organic framework MAGNETISM 
Boosting of the enhanced permeability and retention effect with nanocapsules improves the therapeutic effects of cetuximab被引量：1
《Cancer Biology & Medicine》2020年第2期433-443,共11页Chao Yang Yanli Tan Hongzhao Qi Junhu Zhou Lixia Long Qi Zhan Yunfei Wang Xubo Yuan Chunsheng Kang 
the National Key Research and Development Program(Grant Nos.2016YFC0902502 and 2018YFA0209700);the National Natural Science Foundation of China(Grant Nos.81772667 and 51773151);the Special Construction Innovation Funded Project for Community in Beijing,Tianjin and Hebei of China(Grant No.18247792D).
Objective:The introduction of therapeutic antibodies(tAbs)into clinical practice has revolutionized tumor treatment strategies,but their tumor therapy efficiency is still far below expectations because of the rapid de...
关键词：Endothelial cells EPR effect NANOCAPSULE single dose administration therapeutic antibody 
Microwave Absorption of Crystalline Fe/MnO@C Nanocapsules Embedded in Amorphous Carbon被引量：22
《Nano-Micro Letters》2020年第4期152-167,共16页Gaihua He Yuping Duan Huifang Pang 
Supported by Program for the National Natural Science Foundation of China (Nos. 51577021 and U1704253);the Fundamental Research Funds for the Central Universities (DUT17GF107)
Crystalline Fe/MnO@C core–shell nanocapsules inlaid in porous amorphous carbon matrix(FMCA)was synthesized successfully with a novel confinement strategy.The heterogeneous Fe/MnO nanocrystals are with approximate sin...
关键词：Crystalline nanocapsule Amorphous carbon Core–shell structure Interfacial polarization Microwave absorption 
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