TAR

作品数:402被引量:613H指数:11
导出分析报告
相关领域:医药卫生自动化与计算机技术更多>>
相关作者:孙天麟白龙川李丽敏张玮玮朱珊丽更多>>
相关机构:北京大学南开大学中山大学山东师范大学更多>>
相关期刊:更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划教育部人文社会科学研究基金更多>>
-

检索结果分析

结果分析中...
条 记 录,以下是1-10
视图:
排序:
Navigating the pathways:TAR-DNA-binding-protein-43 aggregation,axonal transport,and local synthesis in amyotrophic lateral sclerosis pathology
《Neural Regeneration Research》2025年第10期2921-2922,共2页Ori Bar Avi Eran Perlson 
Neurons are highly polarized cells with axons reaching over a meter long in adult humans.To survive and maintain their proper function,neurons depend on specific mechanisms that regulate spatiotemporal signaling and m...
关键词:SYNTHESIS LOCAL AGGREGATION 
Blood diagnostic and prognostic biomarkers in amyotrophic lateral sclerosis被引量:1
《Neural Regeneration Research》2025年第9期2556-2570,共15页Yongting Lv Hongfu Li 
Amyotrophic lateral sclerosis is a devastating neurodegenerative disease for which the current treatment approaches remain severely limited.The principal pathological alterations of the disease include the selective d...
关键词:amyotrophic lateral sclerosis BIOMARKER blood biomarkers diagnosis glial fibrillary acidic protein neurofilament light chain PROGNOSIS TAR DNA-binding protein 43 
Neuronal Panx1 drives peripheral sensitization in experimental plantar inflammatory pain
《Military Medical Research》2025年第2期204-219,共16页Qu Xing Antonio Cibelli Greta Luyuan Yang Preeti Dohare Qing-Hua Li Eliana Scemes Fang-Xia Guan David C.Spray 
This work was NIH(R01NS092466),NSFC(U2004201);Central Plains Thousand People Plan of Henan Province(204200510013);Henan Overseas Expertise Introduction Center for Discipline Innovation(CXJD2021002);Key Special Project of Zhengzhou University Disciplinary Construction(XKZDJC202001)。
Background:The channel-forming protein Pannexin1(Panx1)has been implicated in both human studies and animal models of chronic pain,but the underlying mechanisms remain incompletely understood.Methods:Wild-type(WT,n=24...
关键词:Pannexin1(Panx1) Dorsal root ganglion Satellite glial cell Peripheral sensitization Plantar inflammatory pain 
雪语
《大自然探索》2025年第4期78-79,共2页王海纳 
2148年,鹤岗某座煤矿的出入口。矿坑口的积雪在探照灯下泛着幽蓝的光,像是无数细碎的星辰坠落在人间。林雪跪在十年前父亲消失的位置,喉间滚动着那个禁忌的音节:“Kholin-Tar”。声波撞击积雪的刹那,整片雪原突然泛起涟漪。
关键词:探照灯 Kholin-Tar 
A novel loop-structure-based bispecific CAR that targets CD19 and CD22 with enhanced therapeutic efficacy against B-cell malignancies
《Protein & Cell》2025年第3期227-232,共6页Lijun Zhao Shuhong Li Xiaoyi Wei Xuexiu Qi Qiaoru Guo Licai Shi Ji-Shuai Zhang Jun Li Ze-Lin Liu Zhi Guo Hongyu Zhang Jia Feng Yuanyuan Shi Suping Zhang Yu J.Cao 
supported by the National Key R&D Program of China(2019YFA0906100 and 2019YFA0904200 to Y.J.C.);the Shenzhen Science and Technology Innovation Program(JCYJ20180504165501371 to Y.J.C.);the National Natural Science Foundation of China(32171464 and 81872783 to Y.J.C.),the Prevention and Control of COVID-2019 Research Program in University of Guangdong Province(2020KZDZX1176 to S.Z.);the Shenzhen Basic Research Program(JCYJ20180507182203049 to S.Z.);the Shenzhen Key Laboratory Foundation(ZDSYS20200811143757022 to S.Z.).
Dear Editor,Chimeric antigen receptor T(CAR-T)cells have achieved substantial advances in the treatment of B-cell malignancies.Despite high initial response rates,some patients relapse,characterized by targeted antige...
关键词:B cell malignancies therapeutic efficacy targeted antigen loss shalabi bispecific CAR T cells CD 
地胆草中1个新的三萜
《中国中药杂志》2025年第5期1224-1230,共7页丁祖霄 谢红茜 陈林 郝俊杰 罗艳秋 江志勇 徐士奎 
云南省市场监管科学研究计划项目(2022YSJK08);兴滇英才支持计划项目;云南省科技计划项目重大科技专项生物医药专项(202402AA310030);云南省中医药联合专项重点项目(202101AZ070001-164);云南省教育厅高原特色民族药用植物研究科技创新团队项目;国家中医药管理局高水平中医药重点学科建设项目(Zyyzdxk-2023192)。
采用硅胶柱色谱、C18柱色谱、MCI柱色谱以及半制备型高效液相色谱等色谱手段对地胆草90%乙醇提取物的石油醚萃取部分进行化学成分研究,从中分离鉴定了10个化合物。通过1D NMR、2D NMR、MS、IR等波谱数据及理化性质分别鉴定为3β-hydrox...
关键词:地胆草 三萜 3β-hydroxy-6β 7β-epoxytaraxeran-14-ene 
Advancements in biomass gasification and catalytic tar-cracking technologies
《Materials Reports(Energy)》2024年第4期1-19,I0001,共20页Yong-hong Niu Zheng-yang Chi Ming Li Jia-zheng Du Feng-tao Han 
supported by the National Natural Science Foundation of China(52160013,51768054);Inner Mongolia Autonomous Region"Grassland Talent"Science Fund Program(CYY012057);Program for Young Talents of Science and Technology in Universities of Inner Mongolia Autonomous Region(NJYT22062);Inner Mongolia Natural Science Foundation(2021LHMS05026);Inner Mongolia University Research Program(2023RCTD018,2023YXXS023,2024YXXS047).
Biomass,heralded as sustainable“green coal”,plays a crucial role in energy conservation and achieving“dual carbon”objectives through clean conversion.This paper reviews advancements in biomass catalytic gasificati...
关键词:Biomass gasification Composite catalyst Tar cracking Thermal conversion 
Parametric modeling and applications of target scattering centers:a review
《Journal of Systems Engineering and Electronics》2024年第6期1411-1427,共17页YIN Hongcheng YAN Hua 
supported by the National Natural Science Foundation of China(62231001).
The parametric scattering center model of radar tar-get has the advantages of simplicity,sparsity and mechanism relevant,making it widely applied in fields such as radar data compression and rapid generation,radar ima...
关键词:radar target scattering center(SC) parametric model radar target imaging radar target simulation radar tar-get recognition 
Rapid generation and characterization of recombinant HCoV-OC43-VR1558 infectious clones expressing reporter Renilla luciferase
《Biosafety and Health》2024年第6期350-360,共11页Fei Ye Na Wang Qiongge Guan Mengwei Wang Jiewei Sun Desheng Zhai Baoying Huang Ying Zhao Wenjie Tan 
supported by the National Key Research and Development Program of China(2022YFC2304100 and 2021YFA1201003).
Viral infectious clones(ICs)serve as robust platforms for studying viral biology and screening antiviral agents using reverse genetics.However,the molecular profiles and complex limitations of human coronaviruses(HCoV...
关键词:Infectious clones Human coronaviruses(HCoV)-OC43 Transformation-associated recombination(TAR) Reporter Renilla luciferase(Rluc) 
涂装车间智能烤箱控制系统的应用
《现代涂料与涂装》2024年第11期70-72,共3页韩富刚 刘岩 张成 寇锁 张巍文 唐照照 
主要介绍了北京奔驰涂装车间智能烤箱控制系统的基本原理、应用及控制思路。通过分析阐述烤箱系统的结构、原理及工艺参数等信息,研究出一套完整的节能优化方案。
关键词:TAR 能源利用率 智能控制 低碳 
检索报告 对象比较 聚类工具 使用帮助 返回顶部