SHIKONIN

作品数：40被引量：150H指数：7
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相关作者：陈珊珊马晓东李重九罗宏宾朱荃更多>>
相关机构：中国医科大学中国农业大学南京大学浙江中医药大学更多>>
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  • 期刊=Chinese Chemical Lettersx
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Effective assignment of positional isomers in dimeric shikonin and its analogs by ^(1)H NMR spectroscopy
《Chinese Chemical Letters》2024年第5期223-226,共4页Ling-Hao Zhao Hai-Wei Yan Jian-Shuang Jiang Xu Zhang Xiang Yuan Ya-Nan Yang Pei-Cheng Zhang 
funded by the CAMS Innovation Fund for Medical Sciences(CIFMS,No.2021-I2M-1-028).
An approach for distinguishing two types of positional isomers of dimeric shikonin and its analogs was explored with ^(4)JC,H long-range correlation by prolonging the acquisition time at ^(2,3)JC,H values of 2.0 and 8...
关键词：Arnebia euchroma Dimeric hydroxyl naphthoquinones Positional isomers ^(1)H NMR spectroscopy Chemical shift difference 
Design and synthesis of biotinylated dimethylation of alkannin oxime derivatives被引量：2
《Chinese Chemical Letters》2017年第2期453-457,共5页Guang Huang Qing-Qing Meng Wen Zhou Qi-Jing Zhang Jin-Yun Dong Shao-Shun Li 
supported by National Natural Science Foundation of China (No. 81373274);Ph.D. Programs Foundation of Ministry of Education China (No. 20120073110068);Shanghai Biomedical Supporting Funding (No. 15431900600)
DMAKO-05,a novel dimethylation of alkannin oxime derivative,exhibits remarkable anticancer activity as well as excellent cellular selectivity and thus has been considered as a promising antineoplastic agent for colore...
关键词：Alkannin and shikonin oxime derivatives Anticancer activity Biotin probe Molecular target Mitsunobu reaction 
Electroanalytical method for determination of shikonin based on the enhancement effect of cyclodextrin functionalized carbon nanotubes被引量：5
《Chinese Chemical Letters》2015年第5期613-618,共6页Yan-Sha Gao Li-Ping Wu Kai-Xin Zhang Jing-Kun Xu Li-Min Lu Xiao-Fei Zhu Yao Wu 
the National Natural Science Foundation of China(No.51302117);the Natural Science Foundation of Jiangxi Province(Nos.20122BAB216011 and 20122BAB213007);Jiangxi Provincial Department of Education(No.GJJ13258);Postdoctoral Science Foundation of China(No.2014M551857);the Science and Technology Landing Plan of Universities in Jiangxi province (No.KJLD12081) for their financial support of this work
A simple and sensitive electroanalytical method for determination of shikonin, a widely used antitumoral agent, using β-cyclodextrin-functionalized multiwalled carbon nanotubes composite modified glassy carbon electr...
关键词：Shikonin β-Cyclodextrin Multiwalied carbon nanotubes Modified electrode Electrochemical detection 
A Novel Total Synthesis of (±)Shikonin
《Chinese Chemical Letters》2006年第7期871-873,共3页De Feng XU Xiao Juan GUO Zhao Hui XU Shao Shun LI 
A novel total synthesis of （±）shikonin 1 was presented. The key intermediate 6 was achieved by the formylation of 1,8：4,5-bis（methylenedioxy）naphthalene 5 with N-methylformanilide in good yield. It was first rep...
关键词：（±）Shikonin total synthesis prenyllithium. 
New Asymmetric Synthesis of Alkannin and Shikonin被引量：2
《Chinese Chemical Letters》2005年第4期465-467,共3页JianGangZHANC QunLU WenHuDUAN JunCaoCAI 
the National Natural Science Foundation of China[32071532]for financial supports
A new approach for asymmetric synthesis of alkannin and shikonin is presented. The chiral centers of the targets were introduced via an asymmetric C-arylation of protected chiral glyceraldehyde in high de. The two e...
关键词：Asymmetric synthesis ALKANNIN SHIKONIN arylglycerols. 
A Simple Synthesis of dl-Shikonin
《Chinese Chemical Letters》2002年第2期113-114,共2页Qun LU Wen Hu DUAN Jun Chao CAI 
A new facile route for the synthesis of dl-shikonin is presented. Reformatsky reaction assisted cross-coupling of 1, 4, 5, 8-tetramethoxynaphthalene-2-carbaldehyde and ethyl- bromoacetate was employed for introductio...
关键词：SYNTHESIS dl-shikonin Reformatsky reaction. 
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