supported by the National Natural Science Foundation of China(No.21262012);the Natural Science Foundation of Hubei Province(No.2016CFB400)
N-(5-Aryl-1,3,4-thiadiazol-2-yl)-N?-((E)-styryl)ureas 4 a~4 i were designed and synthesized as antitumor agents, and their structures were characterized by IR, 1 H NMR, 13 C NMR,MS and elemental analysis. The single ...
With the introduction of various heterocyclic rings at the benzene part of anthranilic diamides, a series of N-pylidylpyrazolecarboxamide derivatives containing isoxazole, isoxazoline and 1,3,4-thiadiazole rings was d...
A variety of pyrazole derivatives containing 1,3,4-thiadiazole moiety were synthesized under microwave irradiation, and their structures were confirmed by 1H NMR and HRMS. They were evaluated for herbicidal and antifu...
Six new 1,3,4-thiadiazole Schiff base derivatives were synthesized and characterized by IR spectroscopy and ~1H NMR spectrometry, and their anti-corrosion properties and thermal stability were investigated via thermog...
Supported by the National Natural Science Foundation of China(No.81373281), the Program for New Century Excellent Talents in Universities of China(No.NCET-12-0337) and the Shandong Natural Science Foundation for Distinguished Young Scholars, China(No.JQ201319).
Twenty-two novel 1,3,4-thiadiazole derivatives were synthesized using different aromatic acids as starting materials, followed by cyclization, coupling and deprotection reaction. The structures of all the target compo...
To find new lead compounds with high antifungal activity, a series of new thiourea derivatives containing 1,3,4-thiadiazole and thioether skeleton was designed via linking the active sub-structures. The target compoun...
The corrosion inhibition of type 304 austenitic stainless steel by 2-amino-5-ethyl-1, 3, 4-thiadiazole(TTD) compound and the electrochemical behaviour in dilute HCl solution were investigated through potentiodynamic p...
2-(Hydrazinecarbothioyl)-N-substituted hydrazinecarbothioamides react with 2,3,5,6-tetrachloro-1,4-benzoquinone in high yields in a novel fast and facile method to give 5-unsubstituted-1,3,4-thiadiazole-2-amine deri...
funded by the National Natural Science Foundation of China(No.21002090);the Key Innovation Team of Science and Technology in Zhejiang Province(2010R50018-06);the National Key Technologies R&D Program(2011BAE06B03-01)
The title compound 2-(((6-chloropyridin-3-yl)methyl)thio)-5-(pyridin-4-yl)-1,3,4-thiadiazole 5(C26H18Cl2N8S4) was synthesized, and its structure was confirmed by 1H NMR, MS and elemental analyses and X-ray diffraction...
Supported by the National Natural Science Foundation of China(No.20971097) and the Tianjin Municipal Natural Science Foundation, China(No. 13JCYBJC24500).
A series of novel 1,3,4-thiadiazole derivatives possessing benzisoselenazolone scaffold were designed and synthesized, and their antitumor activities against human cervix adenocarcinoma(HeLa), human liver cancer cel...