SCHISANDRIN

作品数：12被引量：46H指数：4
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相关领域：医药卫生更多>>
相关作者：许银燕徐青更多>>
相关机构：淮安市妇幼保健院南京医科大学更多>>
相关期刊：《长春中医药大学学报》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《Pharmacology & Pharmacy》更多>>
相关基金：国家自然科学基金广东省自然科学基金国家重点基础研究发展计划更多>>
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  • 学科=医药卫生—中医学x
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Novel discovery of schisandrin A regulating the interplay of autophagy and apoptosis in oligoasthenospermia by targeting SCF/c-kit and TRPV1 via biosensors被引量：5
《Acta Pharmaceutica Sinica B》2023年第6期2765-2777,共13页Lijuan Ma Boyi Li Jinchen Ma Chunyuan Wu Nan Li Kailin Zhou Yun Yan Mingshuang Li Xiaoyan Hu Hao Yan Qi Wang Yanfei Zheng Zhisheng Wu 
co-supported by National Outstanding Youth Science Fund Project of National Natural Science Foundation of China(No.82022073);National Natural Science Foundation of China(No.82174389);Natural Science Foundation of Beijing Municipality(No.7202115,China);Postdoctoral Research Foundation of China(No.2021M690474)。
Oligoasthenospermia is the primary cause of infertility.However,there are still enormous challenges in the screening of critical candidates and targets of oligoasthenospermia owing to its complex mechanism.In this stu...
关键词：OLIGOASTHENOSPERMIA Male infertility AUTOPHAGY APOPTOSIS BIOSENSOR Schisandrin A. 
Chemoproteomics identifies Ykt6 as the direct target of schisandrin A for neuroprotection
《Chinese Chemical Letters》2023年第6期401-405,共5页Tiantian Wang Yu Zhou Hao Zheng Tao Shen Dongmei Wang Jinlan Zhang 
supported by the CAMS Innovation Fund for Medical Sciences(CIFMS,Nos.2021-I2M-1-069,2022-12M-2-002);Beijing Municipal Natural Science Foundation,China(No.7222259)。
Schisandrin A is a natural dibenzocyclooctene lignan with potent neuroprotective activity.However,the specific mechanisms or direct target proteins have not been clarified up to now.In this study,we designed and synth...
关键词：Schisandrin A Activity-based protein profiling(ABPP) NEUROPROTECTION Ykt6 AUTOPHAGY 
Investigation of in Vitro and in Vivo Metabolism of Schisandrin B from Schisandrae Fructus by Liquid Chromatography Coupled Electrospray Ionization Tandem Mass Spectrometry被引量：1
《Pharmacology & Pharmacy》2015年第8期363-373,共11页Tianxiu Qian Pou Kuan Leong Kam Ming Ko Wan Chan 
Schisandrin B (Sch B) is one of the active dibenzocyclooctadiene lignans found in the Schisandrae Fructus. Experimental studies have shown that Sch B possesses various pharmacological properties, including anti-cancer...
关键词：SCHISANDRIN B METABOLISM DISPOSITION UPLC-MS/MS 
The Sensitization of Anti-Cancer Therapy by Squalene and Schisandrin Through the Modulation of DNA Damage Checkpoint Activity.被引量：1
《长春中医药大学学报》2008年第5期601-601,共1页HiroshiNishida NaotoTatewaki YukiNakajima TetsuyaKonishi NobuoIkekawa 
ATM(ataxia telangiectasia mutated)and ATR(AT and Rad3 related)protein kinases play a crucial role in cellular DNA damage responses.The inhibition of these kinases and/or following effectors lead to an abolishment of o...
关键词：五味子 DNA损伤 中医 肿瘤 治疗方法 
Study on HPLC method to determine contents of Schisandrin A and Schisandrin B in Schisandra chinensis extraction
《Journal of Northeast Agricultural University(English Edition)》2007年第4期323-326,共4页XU Liangmei LI Jianping YAN Changjiang SHAN Anshan 
Supported by National Basic Research Program of China(2004CB11750-5)
The determination method of Schisandrin A and Schisandrin B in Schisandra chinensis was improved with the high performance liquid chromagraphy （HPLC）. The sample was extracted exceedingly in the critical limit of CO...
关键词：HPLC Schisandra chinensis Schisandra A Schisandrin B 
Asymmetric Synthesis of (S)-Dimethyl-4,4′-dimethoxy-5,6,5′,6′-dimethenedioxybiphenyl-2,2′-dicarboxylate
《Chinese Chemical Letters》2005年第2期167-170,共4页SenXiangCHENG LiMinWANG JunBiaoCHANG LingBoQU RongFengCHEN JingXiXIE 
(S)-Dimethyl-4, 4′-dimethoxy-5, 6, 5′, 6′-dimethenedioxy-biphenyl-2, 2′-dicarbonylatewas synthesized in reasonable yield through a series of reactions, including chiral oxazoline-mediated asymmetric Ullmann coupli...
关键词：BIPHENYL Schisandrin C asymmetric Ullmann coupling. 
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