EXCITOTOXICITY

作品数：71被引量：272H指数：7
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相关领域：医药卫生更多>>
相关作者：于洋杨柳马春蕾孙晖王天佑更多>>
相关机构：滨州医学院北京市神经外科科研究所山东大学华东师范大学更多>>
相关期刊：《Chinese Journal of Integrative Medicine》《Frontiers in Biology》《Acta Pharmacologica Sinica》《International Journal of Ophthalmology(English edition)》更多>>
相关基金：国家自然科学基金国家教育部博士点基金国家重点基础研究发展计划湖北省自然科学基金更多>>
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In vitro protective effect of recombinant prominin-1 combined with microRNA-29b on N-methyl-D-aspartateinduced excitotoxicity in retinal ganglion cells
《International Journal of Ophthalmology(English edition)》2023年第11期1746-1755,共10页Jun-Hua Li Guan-Shun Yu Yu-Da Wang Tian-Kun Li 
Supported by Zhejiang Provincial Natural Science Foundation of China(No.LY20H120003).
AIM:To determine the in vitro protective effect of recombinant prominin-1(Prominin-1)+microRNA-29b(P1M29)on N-methyl-D-aspartate(NMDA)-induced excitotoxicity in retinal ganglion cells(RGCs).METHODS:RGC-5 cells were cu...
关键词：Prominin-1 microRNA-29b vascular endothelial growth factor transforming growth factor-β2 
Neuroprotective effect of a dietary supplement against glutamate-induced excitotoxicity in retina
《International Journal of Ophthalmology(English edition)》2019年第8期1231-1237,共7页Takahiro Kurose Eriko Sugano Akihisa Sugai Raki Shiraiwa Mariyo Kato Yoko Mitsuguchi Yoshihiro Takai Kitako Tabata Yoichi Honma Hiroshi Tomita 
Supported by the Rohto Pharmaceutical Co.,Ltd.Furthermore,it was partly supported by Grants-in-Aid for Scientific Research from the Ministry of Education,Culture,Sports,Science and Technology of Japan(No.16H05485; No.16K15729; No.16K11314; No.17H06330)
AIM: To evaluate the neuroprotective effect of a dietary supplement(ClearVision EX~?;CV) against glutamateinduced excitotoxicity in retina.METHODS: We evaluated the protective effects CV on glutamate-induced cell toxi...
关键词：glutamate-induced toxicity retinal GANGLION CELLS HT-22 CELLS PERK 
Dose-dependent effects of NMDA on retinal and optic nerve morphology in rats被引量：1
《International Journal of Ophthalmology(English edition)》2019年第5期746-753,共8页Lidawani Lambuk Azliana Jusnida Ahmad Jafri Igor Iezhitsa Renu Agarwal Nor Salmah Bakar Puneet Agarwal Aimy Abdullah Nafeeza Mohd Ismail 
Supported by Universiti Teknologi MARA [No.600-IRMI/MYRA5/3/BESTARI (004/2017); No.600IRMI/DANA5/3/LESTARI (0076/2016); No.600-IRMI/ My RA5/3/LESTARI (0088/2016)]
AIM: To investigate dose-dependent effects of N-methylD-aspartate(NMDA) on retinal and optic nerve morphology in rats.METHODS: Sprague Dawley rats, 180-250 g in weight were divided into four groups. Groups 1, 2, 3 and...
关键词：GLAUCOMA EXCITOTOXICITY N-methyl-Daspartate retina optic nerve DOSE-DEPENDENT EFFECTS 
Bis(7)-tacrine protects retinal ganglion cells against excitotoxicity via NMDA receptor inhibition被引量：5
《International Journal of Ophthalmology(English edition)》2011年第2期125-130,共6页Zu-Hai Zhang, Jia-Hua Fang 
National Natural Science Foundation of China (No.81000380H1204);Natural Science Foundation of Hubei Province,China (No.2008CDA053);Scientific Research Fund of the Ministry of Health,Hubei Province,China (No.QJX2010-53)
AIM: To investigate whether bis (7)-tacrine, a multifunctional drug, inhibits N-methyl-D-aspartate (NMDA) -activated current in retinal ganglion cells (RGC) and provides neuroprotection against retinal cell damage. ME...
关键词：bis(7)-tacrine N-methyl-D-aspartate receptors EXCITOTOXICITY NEUROPROTECTION 
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