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DOSE-DEPENDENT: 作品数：52被引量：105H指数：5; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：林伟基易涛李良高博郭巍更多>>; 相关机构：澳门科技大学第四军医大学西京医院中国医药大学北京大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划湖北省自然科学基金中国博士后科学基金更多>>

Quorum quenching enzymes disrupt bacterial communication in a sex-and dose-dependent manner: 《Animal Models and Experimental Medicine》2025年第3期473-482,共10页Aneesh Syal Maria Martell Rakesh Sikdar Matthew Dietz Zachary Ziegert Cyrus Jahansouz Mikael H.Elias Christopher Staley; Biotechnology Institute and the MnDrive initiative(to MHE)。; Background:Over the past 50 years,the incidence of obesity has gradually increased,necessitating investigation into the multifactorial contributors to this disease,including the gut microbiota.Bacteria within the huma...; 关键词：MICROBIOME microbiota therapeutics obesity quorum sensing

A dose-dependent bimodal switch by homologous Aux/IAA transcriptional repressors被引量：1: 《Molecular Plant》2024年第9期1407-1422,共16页Hyung-Taeg Cho Minsu Lee Hee-Seung Choi Kwang-Ho Maeng Kyeonghoon Lee Ha-Yeon Lee Anindya Ganguly Hoonyoung Park Chang-Hoi Ho; supported by a grant from the National Research Foundation(NRF-2022R1A2C1007862).; Combinatorial interactions between different regulators diversify and enrich the chance of transcriptional regulation in eukaryotic cells.However,a dose-dependent functional switch of homologous transcriptional repres...; 关键词：AUXIN AUX/IAA dose-dependent regulation root hair transcription TOPLESS(TPL)

Ligand dose-dependent activation of signaling pathways through the gustatory receptor NlGr11 linked to feeding efficacy in Nilaparvata lugens被引量：1: 《Insect Science》2023年第5期1420-1430,共11页Wei-Wen Chen Kai Lin Jun Lv Qin Su Meng-Yi Zhang Kui Kang Wen-Qing Zhang; supported by the National Natural Science Foundation of China(31730073,U1401212);Guizhou Science and Technology Project(qiankeheji-zk[2021]General 135).; Insects often face both conditions with sufficient nutrients and conditions of undernutrition in the field.Through gustatory receptors,insects sense nutrients and regulate their physiological functions such as feeding...; 关键词：feeding efficacy galactose G protein-coupled signaling pathway insect gustatory receptor ionotropic pathway

Pregabalin induced balance disorder,asthenia,edema,and constipation in an elderly adult:A case report: 《World Journal of Clinical Cases》2023年第17期4060-4064,共5页Li-Ping Ma Cheng Wen Tong-Xiang Zhao Xiang-Ming Jiang Jin Gu; BACKGROUND Pregabalin is widely used to treat neuropathic pain associated with postherpetic neuralgia.To our knowledge,this is the first report on simultaneously occurring dose-related adverse drug reactions(ADRs)of b...; 关键词：PREGABALIN Dose-dependent AEs The elderly population Adverse drug reaction Case report

Dose-dependent tandem responses of osteoblasts during osteogenesis: 《Medicine in Novel Technology and Devices》2023年第2期114-122,共9页Yuwei Zhang Lizhen Wang Hongyan Kang Chia-Ying Lin Yubo Fan; The study was supported by National Natural Science Foundation of China(No.12172034,U2241273,11827803,U20A20390);Beijing Municipal Natural Science Foundation(7212205);the 111 project(B13003);the Fundamental Research Funds for the Central Universities.; Irisin,a myokine mainly secreted from contracted skeleton muscle,plays a profound role in bone formation and remodeling.Although irisin has been revealed to elevate bone mass in vivo,details whether there is a dosedep...; 关键词：Irisin OSTEOBLAST Proliferation DIFFERENTIATION Bone formation

Dose-dependent associations of joint aerobic and muscle-strengthening exercise with obesity:A cross-sectional study of 280,605 adults: 《Journal of Sport and Health Science》2023年第2期186-193,共8页Jason A Bennie Ding Ding Katrien De Cocker; Background:Emerging epidemiological evidence suggests that compared to engaging in 1 activity mode alone,a combination of moderate-tovigorous physical activity(MVPA:brisk walking/jogging,cycling)and muscle-strengtheni...; 关键词：Body mass index EPIDEMIOLOGY Public health Resistance exercise

Transcriptome reveals overview of Ca^(2+) dose-dependent metabolism disorders in zebrafish larvae after Cd^(2+) exposure被引量：1: 《Journal of Environmental Sciences》2023年第3期480-491,共12页Biran Zhu Ziniu Wang Lei Lei Yongyong Guo Jian Han Bingsheng Zhou; supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (No. XDA23040401);the National Natural Science Foundation of China (No. 21806091);the Natural Science Foundation of Hubei Province (No. 2020CFB154)。; Cadmium (Cd),a ubiquitous environmental hazardous heavy metal,poses a significant threat to the health of aquatic organisms,including teleosts.Although the toxic profile of Cd is well recognized,little is known regard...; 关键词：Cadmium Calcium Zebrafish larvae TRANSCRIPTOME Metabolism disorder

TDP-35,a truncated fragment of TDP-43,induces dose-dependent toxicity and apoptosis in flies: 《Neural Regeneration Research》2022年第11期2441-2442,共2页Deepak Chhangani Diego E.Rincon-Limas; National Institutes of Health grant R01AG059871(to DERL)。; TAR DNA-binding protein 43(TDP-43)is an essential 414 amino acid protein that regulates multiple aspects of RNA biogenesis,processing,and transport.It localizes primarily in the nucleus,but abnormal translocation and ...; 关键词：DEGENERATION TDP

Dose-Dependent, Frequency-Dependent, and Cumulative Effects on Cardiomyocyte Injury and Autophagy of 2.856 GHz and 1.5 GHz Microwave in Wistar Rats: 《Biomedical and Environmental Sciences》2022年第4期351-355,共5页ZHANG Bo ZHANG Jing YAO Bin Wei XU Xin Ping WANG Hui ZHAO Li DONG Ji WANG Hao Yu TAN Sheng Zhi PENG Rui Yun; With the in creasing use of microwave technology in wireless communication,medical research,and other fields,the risk of energy leakage and excessive human exposure requires more attention.Exposure to a certain freque...; 关键词：ORGANS MICROWAVE consequences

Effect of exercise on inhibitory control is dose-dependent for adolescents: 《Sports Medicine and Health Science》2022年第1期54-60,共7页Xin Li Zhengzhen Wang Yan Wang Xiaotong Li Dongfeng Li; supported by National Key Research and Development Program Major Prevention and Control Research on Chronic Noncommunicable Diseases(2016YFC1300202).; Adolescence is an important stage for brain maturation.To investigate the effect of different exercise doses on inhibitory control in adolescents aged 12 to 14-year old,an after-school exercise program was offered 5 d...; 关键词：Long-term exercise interventions Cardiorespiratory fitness DOSE-RESPONSE Adolescents Inhibitory control COGNITION Physical activity

DOSE-DEPENDENT