EXCITOTOXICITY

作品数：71被引量：272H指数：7
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相关领域：医药卫生更多>>
相关作者：于洋杨柳马春蕾孙晖王天佑更多>>
相关机构：滨州医学院北京市神经外科科研究所山东大学华东师范大学更多>>
相关期刊：《Chinese Journal of Integrative Medicine》《Frontiers in Biology》《Acta Pharmacologica Sinica》《International Journal of Ophthalmology(English edition)》更多>>
相关基金：国家自然科学基金国家教育部博士点基金国家重点基础研究发展计划湖北省自然科学基金更多>>
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Effect of neuronal excitotoxicity on Munc18-1 distribution in nuclei of rat hippocampal neuron and primary cultured neuron
《Neuroscience Bulletin》2011年第3期163-172,共10页张彦平 万萍 王洪权 赵红 许玉霞 杨茹 朱粹青 
supported by grants from the National Natural Science Foundation of China (No. 81071017, 30470536, 90919004)
Objective Muncl8-1 has an important role in neurotransmitter release, and controls every step in the exocy- totic pathway in the central nervous system. In the present study, whether epileptic seizure causes a change ...
关键词：Munc 18-1 NUCLEUS kainic acid GLUTAMATE HIPPOCAMPUS primary cultured neurons 
Regulatory effects of insulin-like growth factor-1 on the expression of sensory neuropeptide mRNAs in cultured dorsal root ganglion neurons with excitotoxicity induced by glutamate被引量：4
《Neuroscience Bulletin》2010年第2期126-132,共7页宫荟萃 杨向东 刘真 邢子英 王怀经 李振中 
supported by the Natural Sciences Foundation of Shandong Province, China(No. Z2006C06);the Science and Technology Development Project of Jinan Municipality of Shandong Province,China (No. 200705083, 200807046)
Objective To determine the effects of insulin-like growth factor-1 （IGF-1） on the expression of preprotachykinin （PPT） mRNA encoding substance P （SP） and calcitonin gene-related peptide （CGRP） mRNA in cultured...
关键词：insulin-like growth factor-1 GLUTAMATE substance P calcitonin gene-related peptide dorsal root ganglion 
Excitotoxicity effects of glutamate on human neuroblastoma SH-SY5Y cells via oxidative damage被引量：3
《Neuroscience Bulletin》2010年第1期8-16,共9页孙中伟 张蓝 竺淑佳 陈温纯 梅兵 
supported by thegrants from National Natural Science Foundation of China(No. 30870790);Shanghai Science and Technology Commis-sion (No. 06DZ19003);in part by National Basic ResearchDevelopment Program (973) of China (No. 2009CB918402)
Objective To investigate the mechanisms of excitotoxic effects of glutamate on human neuroblastoma SH-SY5Y cells. Methods SH-SY5Y cell viability was measured by MTT assay. Other damaged profile was detected by lactate...
关键词：GLUTAMATE EXCITOTOXICITY cytosolic calcium oxidative damage 
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