OBJECTIVE Liver cancer is one of the most common causes of cancer related deaths worldwide,specially,in China.Hinesol,extracted from Atractylodeslance a(Thunb.) DC.has been proved that has anti-cancer effect in leukem...
Supported by the National Natural Science Foundation of China(No.20606013);the Produce-learn-research Project of Shenzhen Scinence and Technology Program(No.2008342);the Fundamental Research Project of Shenzhen Science and Technology, China(No.JC200903120089A)
To improve the encapsulation efficiency and minimize particle agglomeration of liposomes, rapid expansion from supercritical to surfactant solution(RESSS) was applied to self-assembly of liposomes entrapping hinesol...
Stereoselective total synthesis of (±)hinesol 1 was achieved from readily available stafting materials and thorough mild reaction conditions. The structure of synthetic hinesol was confirmed by chemical transformation.
A mild base-catalyzed retro-benzilic acid rearrangement of a proto-[2+2]photocycloadduct, formed in highly steroselective photoaddition of methyl 2,4-dioxo-pentanoate to 1,5-dimethyl-6-methylenecyclohexene, afforded ...