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Not just a combination: a fully-integrated strategy of cellular therapy for acute myeloid leukemia expressing CD7, a heretofore elusive target
《Science China(Life Sciences)》2025年第4期1202-1204,共3页Norbert-Claude Gorin 
Acute myeloid leukemia(AML) and its treatment have remained, for long, an area of slow but constant therapeutic progress as well as of permanent frustration. Chemotherapy has initially been and still is part of the ba...
关键词：molecular biology major leukemic clone next generation sequencing clones subclones escapin acute myeloid leukemia aml acute myeloid leukemia CD cellular therapy 
Establishing a human pancreatic stem cell line and transplanting induced pancreatic islets to reverse experimental diabetes in rats被引量：9
《Science China(Life Sciences)》2008年第9期779-788,共10页XIAO Mei AN LiLong YANG XueYi GE Xin QIAO Hai ZHAO Ting MA XiaoFei FAN JingZhuang ZHU MengYang DOU ZhongYing 
the National Basic Research Program of China(Grant No.G1999054301);the High-tech Research Program(863 Program)of the Ministry of Science and Technology of China(Grant No.2002AA216161);the National Natural Science Foundation of China(Grant No.39970363);the Emphasis Foundation of Ministry of Education of China(2003-2005);the Emphasis Foundation of Shaanxi Province(Grant No.2002K01-G3);the Natural Science Foundation of Guangdong Province(Grant No.04011471);the Science Foundation of Educational office of Guangdong Province(Grant No.2003-1009)
The major obstacle in using pancreatic islet transplantation to cure type I and some type II diabetes is the shortage of the donors. One of ways to overcome such obstacle is to isolate and clone pancreatic stem cells ...
关键词：pancreatic stem cell mono-clone differentiation transplantation HUMAN 
Molecular characterization and expression analysis of caveolin-1 in pig tissues被引量：2
《Science China(Life Sciences)》2008年第7期655-661,共7页WANG Chong1,MEI YingJie 1,LI Li 1,MO DeLin 2,LI JiaQi 1,ZHANG Hao 1,TIAN XingGuo 1 &CHEN YaoSheng2 1College of Animal Science,South China Agricultural University,Guangzhou 510642,China 2School of Life Science,Sun Yat-Sen University,Guangzhou 510006,China 
National Natural Science Foundation of China(Grant NO.30300249);Key Project of Chinese National Project for Fundamental Research and Development(973 Project)(Grant NO.2004CB117506);Group Project of Guangdong NaturalScience Foundation(Grant NO.04205804)
Members of the caveolin family played important roles during fundamental cellular processes,such as regulation of cell morphology,migration,and gene expression in muscle cells.In this study,caveolin-1 (Cav-1),one of t...
关键词：CAVEOLIN FAMILY CLONE expression analysis real-time quantify PCR 
Complete nucleotide sequence of a novel porcine circovirus-like agent and its infectivity in vitro被引量：14
《Science China(Life Sciences)》2008年第5期453-458,共6页WEN LiBin1, HE KongWang1, YANG HanChun2, NI YanXiu1, ZHANG XueHan1, GUO RongLi1 & PAN QunXin1 1 Key Laboratory of Animal and Poultry Diseases Diagnostic of the Ministry of Agriculture, Jiangsu Academy of Agricultural Sciences, Nanjing 210014, China 2 Key Laboratory of Preventive Veterinary Medicine of Ministry of Agriculture, College of Veterinary Medicine, China Agricultural University, Beijing 100094, China 
the State Key Basic Research Project (973 project) of China (Grant No. 2007CB116308);Planned Projects for Postdoctoral Research Funds of Jiangsu Province, China (Grant No. 5910602);Postdoctoral Funds of Jiangsu Academy of Agricultural Sciences, China (Grant No. 6510501)
A novel agent (hence termed as P2) was isolated from pig sera in China, which contained covalently bound circular genomic DNAs of 993 nucleotides. Sequence analyses indicated that the agent was closely related to the ...
关键词：P2 PORCINE CIRCOVIRUS molecular CLONE PK-15 cells 
GISH and BAC-FISH study of apomictic Beta M14被引量：1
《Science China(Life Sciences)》2007年第2期242-250,共9页GE Yan1,HE GuangChun2,WANG ZhiWei1,GUO DeDong1,QIN Rui2 & LI RongTian1 1 Key Laboratory of Biochemistry and Molecular Biology,College of Life Sciences,Heilongjiang University,Harbin 150080,China 2 Key Laboratory of Ministry of Education for Plant Developmental Biology,College of Life Sciences,Wuhan University,Wuhan 430072,China 
the National Transgene Scientific Program (Grant No. JY03A2402);the Postdoctoral Science Foundation of Heilongjiang Province
Apomixis is a means of asexual reproduction by which plants produce embryos without fertilization and meiosis,therefore the embryo is of clonal and maternal origin.Interspecific hybrids between dip-loid B.vulgaris(2n=...
关键词：BETA APOMIXIS BAC CLONE two-color FISH hemizygosity 
Characteristics of the microbial community in rhizosphere of Camptotheca acuminata cultured with exotic invasive plant Eupatorium adenophorum被引量：7
《Science China(Life Sciences)》2007年第1期22-30,共9页ZU YuanGang1, GAO ChongYang1, WANG WenJie1, YANG FengJian1, LIU Ying1, WANG Min1 & ZHAO YangGuo2 1 Key Laboratory of Forest Plant Ecology, Ministry of Education, Northeast Forestry University, Harbin 150040, China 2 School of Municipal and Environmental Engineering, Harbin Institute of Technology, Harbin 150090, China 
the Excellent Young Teacher’s Innovation Foundation of Northeast Forestry University to Yang FengJian,;the Key Research Fund of Ministry of Educa-tion of China (Grant No.104191) ;the Forestry Noxious Plant Investigation Fund of State Forestry Administration of China to Zu YuanGang
The traditional culture-dependent plate counting and culture-independent small-subunit-ribosomal RNA gene-targeted molecular techniques, Single-Strand Conformation Polymorphism (SSCP) and ter-minal Restriction Fragmen...
关键词：Camptotheca acuminata rhizospheric MICROBE EUPATORIUM adenophorum SINGLE-STRAND Conformation POLYMORPHISM (SSCP) terminal Restriction Fragment Length POLYMORPHISM (tRFLP) 16S rDNA CLONE library 
cDNA cloning, functional expression and cellular localization of rat liver mitochondrial electron-transfer flavoprotein-ubiquinone oxidoreductase protein
《Science China(Life Sciences)》2005年第4期357-367,共11页HUANG Shengbing SONG Wei LIN Qishui 
This project was supported by the Knowledge Innovation Program of the Chinese Academy of Sciences.
A membrane-bound protein was purified from rat liver mitochondria.After being di-gested with V8 protease,two peptides containing identical 14 amino acid residue sequences were obtained.Using the 14 amino acid peptide ...
关键词：electron transfer flavoprotein ubiquinone oxidoreductase PRECURSOR rat protein purification gene clone tissuespecificity. 
Analysis and location of a rice BAC clone containing telomeric DNA sequences
《Science China(Life Sciences)》1999年第1期68-73,共6页翟文学 陈浩 颜辉煌 严长杰 王国梁 朱立煌 
BAC2, a rice BAC clone containing (TTTAGGG)n homologous sequences, was analyzed by Southern hybridization and DNA sequencing of its subclones. It was disclosed that there were many tandem repeated satellite DNA sequen...
关键词：RICE BAC CLONE telomeric SEQUENCES telomere-associated sequences. 
Isolation and mapping of bacterial artificial chromosome (BAC) clone containing telomere-associated sequence
《Science China(Life Sciences)》1998年第6期617-622,共6页巩学千 陈受宜 龚继明 刘峰 
Using single primer (TTTAGGG)\-3 or (CCCTAAA)\-3CCC corresponding to rice telomeric repeat sequences, two fragments were amplified from rice genomic DNA and named Tas1 and Tas2. These two fragments did not show polymo...
关键词：rice BAC LIBRARY construction TAS BAC CLONE RFLP map. 
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