云南高校图书馆联盟文献共享服务平台- CAVEOLIN

CAVEOLIN: 作品数：66被引量：210H指数：7; 导出分析报告; 相关领域：医药卫生更多>>; 相关作者：韩坤廖端芳苏友新陈冬冬邹伟更多>>; 相关机构：辽宁师范大学南华大学广西医科大学第二军医大学更多>>; 相关期刊：更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划湖南省自然科学基金福建省自然科学基金更多>>

The anti-neoplastic effects of metformin modulate the acquired phenotype of fbroblast cells in the breast cancer-normal fbroblast co-culture system: 《Oncology Research》2024年第3期477-487,共11页SAMANEH MOSTAFAVI ZUHAIR MOHAMMAD HASSAN; the National Institute for Medical Research Development(NIMAD;Grant No.995813).; Intracellular communications between breast cancer and fibroblast cells were reported to be involved in cancer proliferation,growth,and therapy resitance.The hallmarks of cancer fibroblast interactions,consisting of c...; 关键词：Caveolin 1 Lactic acid METFORMIN NIH 3T3 cells Neoplasms

Caveolin‑1 is critical for hepatic iron storage capacity in the development of nonalcoholic fatty liver disease: 《Military Medical Research》2024年第2期206-227,共22页Guang-Hui Deng Chao-Feng Wu Yun-Jia Li Hao Shi Wei-Chao Zhong Mu-Keng Hong Jun-Jie Li Jia-Min Zhao Chang Liu Meng-Chen Qin Zhi-Yun Zeng Wei-Min Zhang Ken Kin Lam Yung Zhi-Ping Lv Lei Gao; financially supported by the National Natural Science Foundation of China(82074131,81774170,82260926);the Guangdong Basic and Applied Basic Research Foundation(2018B030306012,2022A1515220179,2021A1515011667);the Outstanding Youth Development Scheme project of Southern Medical University(G621299870);the Young Elite Scientists Sponsorship Program by CACM(2021-QNRC2-B28);the China Postdoctoral Science Foundation(2022M721532).; Background:Nonalcoholic fatty liver disease(NAFLD)is associated with disordered lipid and iron metabolism.Our previous study has substantiated the pivotal role of Caveolin-1(Cav-1)in protecting hepatocytes and mediati...; 关键词：CAVEOLIN-1 Nonalcoholic fatty liver disease Iron metabolism FERRITIN Oxidative stress

Shear stress regulation of nanoparticle uptake in vascular endothelial cells: 《Regenerative Biomaterials》2023年第1期1048-1059,共12页Hongping Zhang Ziqiu Hu Jinxuan Wang Jianxiong Xu Xiangxiu Wang Guangchao Zang Juhui Qiu Guixue Wang; supported by the National Natural Science Foundation of China(12032007,31971242)to G.W.;the Chongqing Science and Technology Bureau(cstc2019jcyj-zdxmX0028)to G.W.;JinFeng Laboratory,Chongqing,China(jfkyjf202203001)to G.W.; Nanoparticles(NPs)hold tremendous targeting potential in cardiovascular disease and regenerative medicine,and exciting clinical applications are coming into light.Vascular endothelial cells(ECs)exposure to different m...; 关键词：shear stress nanoparticle uptake endothelial cell CLATHRIN CAVEOLIN

Engineering caveolin-mediated endocytosis in Saccharomyces cerevisiae: 《Synthetic and Systems Biotechnology》2022年第4期1056-1063,共8页Qian Zhang Ning Li Yunbin Lyv Shiqin Yu Jingwen Zhou; This work was supported by the Foundation for Innovative Research Groups of the National Natural Science Foundation of China(32021005);the National Natural Science Foundation of China(21908078).; As a potential substitute for fatty acids,common low-cost oils could be used to produce acetyl-CoA derivatives,which meet the needs of low-cost industrial production.However,oils are hydrophobic macromolecules and can...; 关键词：OIL CAVEOLIN-1 β-Oxidation (2S)-Naringenin Saccharomyces cerevisiae

Caveolin-1-deficient fibroblasts promote migration,invasion,and stemness via activating the TGF-β/Smad signaling pathway in breast cancer cells被引量：4: 《Acta Biochimica et Biophysica Sinica》2022年第11期1587-1598,共12页Qingyun Huang Longyuan Wu Yi Wang Xinyu Kong Xinhua Xiao Qiyuan Huang Miao Li Yujia Zhai Fuxiu Shi Ruichen Zhao Junpei Zhong Lixia Xiong; This work was supported by the National Natural Science Foundation of China(Nos.31860317 and 32160169);the Key Project of Jiangxi Provincial Natural Science Foundation(No.20212ACB206040);the National Natural Science Foundation of Jiangxi Province(No.20202BAB206056);the postgraduate innovation special fund project of Nanchang University(No.YC2020-S049);the Key Laboratory of Functional and Clinical Translational Medicine,Fujian Province University(No.XMMCFCTM202103);the college students innovation training program of Nanchang University(Nos.202110403005,S202010403034,2021CX142 and 2020CX263).; Cancer-associated fibroblasts(CAFs)represent one of the main components in the tumor stroma and play a key role in breast cancer progression.Transforming growth factor-β(TGF-β)has been established to mediate breast ...; 关键词：caveolin 1 cancer-associated fibroblasts breast neoplasms epithelial-mesenchymal transition transforming growth factor-β

RNA特异性腺苷脱氨酶1与Caveolin 1在脓毒症相关肝损伤中的作用及机制: 《中国普通外科杂志》2022年第7期913-919,共7页尹朝奇陶如意王少华陈佳唐封杰刘灿刘岱松陈舒悦周建大陈丰原; 湖南省科技厅技术创新计划基金资助项目(2017SK50125)。; 背景与目的:脓毒症相关肝损伤(SRLI)发病机制尚不清楚,细菌内毒素(LPS)对肝脏血管内皮细胞的炎症损害可能是重要环节。前期研究提示,RNA特异性腺苷脱氨酶1 (ADAR1)可能通过调控内皮细胞功能相关蛋白Caveolin 1 (Cav-1)在参与血管内皮应...; 关键词：脓毒症肝损伤内皮细胞腺苷脱氨酶1 窖蛋白1

Caveolin 3蛋白与心脏Kv1.5钾通道的相互作用及鉴定: 《岭南心血管病杂志》2020年第6期709-715,718,共8页马青艳林吉进黄蕾; 广东省自然科学基金项目重点项目(项目编号:2017B030311010);广州市科技计划项目(项目编号:202002030088)。; 目的探索caveolin 3蛋白与Kv1.5钾通道是否存在相互作用,并进一步明确caveolin3对心脏Kv1.5钾通道功能的调控作用。方法 (1)将携带caveolin 3的N端片段的pGBKT7载体转染Y187,与含人类心脏cDNA文库进行酵母双杂交,筛选与caveolin 3存在...; 关键词：caveolin 3 KCNA5 蛋白与蛋白的相互作用酵母双杂交技术膜片钳技术

Effect of Gubi prescription on caveolin-1 expression and phosphoinositide 3 kinase/protein kinase B and Fas signal pathways in rats with knee osteoarthritis被引量：5: 《Journal of Traditional Chinese Medicine》2020年第2期224-235,共12页He Xiaojin Wang Lei Zhou Xueping Xu Luzhou Cao Jing Wang Ruirui Wang Min Xie Guoqian; Supported by Grants from the Training Project for Young and Middle-aged Academic Leaders of"Jiangsu 333 Project"and"High Level Health Personnel Six One Project"of the Jiangsu Health Planning Commission Study on the Molecular Mechanism of Gubi Prescription in the Treatment of KOA Based on the Effect of Caveolin-1 on Chondrocyte Apoptosis Related Signal Transduction Pathway(LGY2016014);Research Project for Clinical Talents of Chinese Medicine of Jiangsu Province。; OBJECTIVE: To investigate the effects of Gubi prescription on the expression of caveolin-1, and the phosphoinositide 3 kinase/protein kinase B(PI3 K/Akt) and Fas signal pathways in rats with knee osteoarthritis(KOA).M...; 关键词：Osteoarthritis knee Caveolin 1 Phosphatidylinositol 3-kinase Superoxide dismutase MALONDIALDEHYDE Nitric oxide Interleukin-1beta Gubi prescription

壮骨健膝方含药血清对人退变关节软骨细胞caveolin-p38MAPK信号通路的影响被引量：5: 《中华中医药杂志》2019年第9期4055-4059,共5页洪振强滕方舟郭洁梅何俊君苏友新; 国家自然科学基金项目(No.81072828)~~; 目的:观察壮骨健膝方含药血清对人退变关节软骨细胞caveolin-p38MAPK信号通路关键信号分子及下游效应产物的影响,阐明该方含药血清保护人退变关节软骨细胞的机制。方法:取正常人及膝骨关节炎(KOA)患者软骨标本体外分离软骨细胞并培养至...; 关键词：壮骨健膝方人软骨细胞 caveolin-p38MAPK信号通路肿瘤坏死因子-α 白细胞介素-1β 基质金属蛋白酶-3 基质金属蛋白酶-13

人血脑屏障通透性相关基因Caveolin-1的克隆及其蛋白表达、纯化: 《中国医药导报》2018年第32期13-15,23,共4页招树涛徐永健陈浩云; 广东省中医药局科研项目(20161048); 目的克隆与人血脑屏障通透性相关基因Caveolin-1,并在大肠埃希菌中表达,最后进行蛋白纯化、鉴定。方法根据基因库中收录的Caveolin-1基因序列,设计其上下游引物,经过PCR反应合成Caveolin-1双链,然后与pET28a(+)载体重组,筛选阳性克隆并...; 关键词：血脑屏障通透性相关基因 Caveolin- 1 克隆表达纯化

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