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COVID-19 induces new-onset insulin resistance and lipid metabolic dysregulation via regulation of secreted metabolic factors
《Signal Transduction and Targeted Therapy》2022年第1期270-281,共12页Xi He Chenshu Liu Jiangyun Peng Zilun Li Fang Li Jian Wang Ao Hu Meixiu Peng Kan Huang Dongxiao Fan Na Li Fuchun Zhang Weiping Cai Xinghua Tan Zhongwei Hu Xilong Deng Yueping Li Xiaoneng Mo Linghua Li Yaling Shi Li Yang Yuanyuan Zhu Yanrong Wu Huichao Liang Baolin Liao Wenxin Hong Ruiying He Jiaojiao Li Pengle Guo Youguang Zhuo Lingzhai Zhao Fengyu Hu Wenxue Li Wei Zhu Zefeng Zhang Zeling Guo Wei Zhang Xiqiang Hong Wei kang Cai Lei Gu Ziming Du Yang Zhang Jin Xu Tao Zuo Kai Deng Li Yan Xinwen Chen Sifan Chen Chunliang Lei 
This study was supported by the joint emergency grants for prevention and control of SARS-CoV-2 of Ministry of Science and Technology of China,Guangdong Science and Technology Department and Guangzhou Municipal Science and Technology Bureau(2020B111108001);Guangdong Science and Technology Department(2020B121206001&2020B1212030004);The funders had no role in study design,data collection and analysis,or preparation of the manuscript.
Abnormal glucose and lipid metabolism in COVID-19 patients were recently reported with unclear mechanism.In this study,we retrospectively investigated a cohort of COVID-19 patients without pre-existing metabolic-relat...
关键词：metabolism mechanism resistance 
结核分枝杆菌CFP10-ESAT6融合蛋白的真核表达及其牛结核病诊断价值评价被引量：3
《农业生物技术学报》2015年第2期267-273,共7页时振华 孟闯 徐正中 万婷 单法 陈祥 焦新安 
国家基础研究发展计划(973)项目(No.2012CB518805);国家星火计划项目(No.2014GA690017);江苏高校优势学科建设工程和校"新世纪人才工程"资助项目
本研究旨在利用毕赤酵母(Pichia pastoris)系统融合表达结核分枝杆菌(Mycobacterium tuberculosis,MTB)的培养滤液蛋白10(culture filter protein 10,CFP10)和早期分泌抗原靶6蛋白(earlier secreted antigen target 6,ESAT6),并评价其...
关键词：结核分枝杆菌 培养滤液蛋白10(CFP10) 早期分泌抗原靶6蛋白(ESAT6) 牛结核病 γ-干扰素(IFN-γ)释放实验 Culture filter protein 10 (CFP10) Eearlier SECRETED antigen target 6 (ESAT6) 
Studies on the Secretion of Organic Acids from Roots of Two-year-old Larix olgensis under Nutrient and Water Stress
《Agricultural Science & Technology》2014年第6期1015-1019,共5页宋金凤 杨迪 马瑞 黄文斌 刘永 
Supported by National Natural Science Foundation of China(31370613);Major State Basic Research Development Program of China(973 Program)(2011CB403202);Project of General Administration of Quality Supervision,Inspection and Quarantine of China(2009IK177);Fundamental Research Fund for the Central Universities(DL12CA01)~~
[Objective] This study aimed to investigate the effects of nutrient and water stress on the secretion of organic acids from roots of two-year-old Larix olgensis. [Method] Different nutrient and water stress conditions...
关键词：Nutrient stress Water stress Two-year-old Larix olgensis Organic acidssecreted from roots 
Organic Acids Secreted from Plant Roots under Soil Stress and Their Effects on Ecological Adaptability of Plants被引量：12
《Agricultural Science & Technology》2014年第7期1167-1173,共7页黄文斌 马瑞 杨迪 刘星平 宋金凤 
Supported by National Natural Science Foundation of China(31370613);Major State Basic Research Development Program of China(973 Program)(2011CB403202);Fundamental Research Funds for the Central Universities(DL12CA01)~~
[Objective] In this study,the secretion of organic acids from plant roots under soil nutrient and water stress and the effects of organic acids on ecological adaptability of plants were investigated,which provided the...
关键词：Nutrient stress Water stress Organic acids secreted from plant roots Plant ecological adaptability 
Tumor-secreted miR-214 induces regulatory T cells： a major link between immune evasion and tumor growth被引量：36
《Cell Research》2014年第10期1164-1180,共17页Yuan Yin Xing Cai Xi Chen Hongwei Liang Yujing Zhang Jing Li Zuoyun Wang Xiulan Chen Wen Zhang Seiji Yokoyama Cheng Wang Liang Li Limin Li Dongxia Hou Lei Dong Tao Xu Takachika Hiroi Fuquan Yang Hongbin Ji Junfeng Zhang Ke Zen Chen-Yu Zhang 
We thank ProfAlexander Rudensky （Memorial Sloan-Kettering Cancer Center, New York） for diphtheria toxin-treated Foxp3DrR mice. We thank Drs Zheng-Gang Liu （Cancer Research Institute, NIH） and Dan Wu （Yale University） for their comments on the manuseirpt. This work was supported by grants from the National Basic Research Program of China （973 Program; 2014CB542300）, the National Natural Science Foundation of China （81101330, 31271378 and 81250044）, the Natural Science Foundation of Jiangsu Province （BK2011013 and BK2012014） and the Research Special Fund for Public Welfare Industry of Health （201302018）. This work was also supported by the program for New Century Excellent Talents in University from the Ministry of Education of China （NCET- 12-0261）.
An increased population of CD4＋CD25highFoxp3＋ regulatory T cells （Tregs） in the tumor-associated microenvi- ronment plays an important role in cancer immune evasion. However, the underlying mechanism remains uncle...
关键词：secreted microRNA regulatory T cell PTEN MICROVESICLE immune evasion TUMOR 
Flank gland-secreted putative chemosignals pertaining to photoperiod,endocrine states,and sociosexual behavior in golden hamsters
《Current Zoology》2010年第6期800-812,共13页Ying-Juan LIU Da-Wei WANG Lixing SUN Jin-Hua ZHANG Jian-Xu ZHANG 
supported by grants from the National Basic Research Program of China (973 Program,no.2010CB833900-2);the Chinese NSF (no.30870297)
Behavioral studies have shown that flank glands are involved in chemical communication in golden hamsters Mesocricetus auratus but little chemical analysis has been conducted on volatiles arising from these glands. Us...
关键词：Dominance Flank gland GONADECTOMY PHOTOPERIOD Putative pheromone Testosterone 
Secreted Expression of S-adenosy-L-methionine Synthetase in Pichia pastoris被引量：6
《Agricultural Science & Technology》2009年第2期49-53,共5页王莲哲 张现青 李洋 杨广笑 何光源 
国家“973”计划项目(2002CB111302)~~
[Objective] The research aimed to study the secreted expression of S-edenosyl-L-methionine synthetase （SAMS） in Pichia pastoris. Method ] The gene coding SAMS, from the genomic DNA of Saccharomyces cerevisiae, was ...
关键词：SAM Pichia pastoris pPICgK Secreted expression 
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