SULFONAMIDE

作品数：73被引量：62H指数：4
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相关领域：理学医药卫生更多>>
相关作者：池志宏牛犁王月王占友缪晓玲更多>>
相关机构：西南大学中国医科大学清华大学宁德师范高等专科学校更多>>
相关期刊：《光谱学与光谱分析》《International Journal of Organic Chemistry》《Agricultural Biotechnology》《Journal of Chinese Pharmaceutical Sciences》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划宁德师专科研基金国家高技术研究发展计划更多>>
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Heterocyclic Synthesis via Enaminones: Synthesis and Molecular Docking Studies of Some Novel Heterocyclic Compounds Containing Sulfonamide Moiety
《International Journal of Organic Chemistry》2014年第1期68-81,共14页Ahmed Abd El-Hameed Hassan 
4-Acetyl-N, N-diethylbenzenesulfonamide (1) was condensed with dimethylformamide dimethy-lacetal (DMF-DMA) to yield the enaminone, which reacts readily with different reagents to give the corresponding pyrazoles, tria...
关键词：DMF-DMA PYRAZOLES BENZOFURAN Pyranone Pyridine PYRIMIDINE Doking 
Design, synthesis and in vitro antitumor evaluation of novel diaryl urea derivatives bearing sulfonamide moiety被引量：2
《Science China Chemistry》2013年第11期1564-1572,共9页LUO Can TANG Ke LI Yan YIN DaLi CHEN XiaoGuang HUANG HaiHong 
financially supported by the National Science&Technology Major Project(2009ZX09301-003-9-1)
A novel series of diaryl urea derivatives bearing sulfonamide moiety have been designed and synthesized. Their in vitro antitumor effect against human cancer cell lines MX-1, A375, HepG2, Ketr3 and HT-29 was screened ...
关键词：diaryl urea derivatives SULFONAMIDE SORAFENIB antitumor activity 
Novel Thiazolopyrane and Thiazolopyranopyrimidine Derivatives Carrying a Sulfonamide Moiety of Expected Cytotoxic and Radiosensitizing Activities
《材料科学与工程（中英文B版）》2011年第6期747-758,共12页Mostafa M. Ghorab Mohamed A. Shaaban Hanan M. Refaat Helmy I. Heiba Sara S. Ibrahim 
关键词：放射增敏剂 衍生物 药物成分 细胞毒性 磺胺类 化合物结构 小说 MCF7细胞 
Synthesis of Certain New Thiazole Derivatives Bearing a Sulfonamide Moiety with Expected Anticancer and Radiosensitizing Activities被引量：1
《材料科学与工程（中英文A版）》2011年第5X期684-691,共8页Mostafa Mohamed Ghorab Dalai A. Abou El Ella Helmy I. Heiba Aiten M. Soliman 
关键词：噻唑衍生物 抗癌活性 合成 增敏 放射 胺基团 轴承 分子设计 
Evaluation of the Antitumor and Radiosynthetizing Activity of a Novel Quinoline Sulfonamide Derivative (PIQSA) as a Histone Deacetylase Inhibitor
《Journal of Cancer Therapy》2011年第4期567-578,共12页Eman Noaman Nadia Fahmy Raafat Yousri Omama El Shawi Maha Ghazy 
Inhibition of histone deacetylases (HDACs) is emerging as a new strategy in cancer therapy. In the present work a novel pyrimido-quinoline benzene sulfonamide (PIQSA compound) was designed and synthesized postulating ...
关键词：ANTITUMOR Radiosynthetization QUINOLINE Derivative SULFONAMIDE MOIETY HDACI Apoptosis Cell Cycle DNA FRAGMENTATION 
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