supported by the National Natural Science Foundation of China(32171359,31971292,32025021 and 32111540257);the General Research Program of Zhejiang Provincial Department of Health(WKJ-ZJ-2137);the Zhejiang Province Financial Supporting(2020C03110 and 2023C04017);the Key Scientific and Technological Special Project of Ningbo City(2020Z094);the Natural Science Foundation of Ningbo(202003N4001,2021J240 and 20221JCGY010661).
Since apoptosis of foam,cells can induce plaque instability,reducing intracellular lipid content while protecting foam cells from apoptosis is beneficial for the safe and efficient therapy of atherosclerosis.In this s...
This work was supported by Natural Science Foundation of China(32171359,32025021,31971292);National Key R&D Program of China(2019YFA0405603,2018YFC0910601);Zhejiang Province Financial Supporting(LGF19C100001,2020C03110);Key Laboratory of Diagnosis and Treatment of Digestive System Tumors of Zhejiang Province(No.2019E10020);Zhejiang Provincial Natural Science Foundation of China(LY20H020002);General research program of Zhejiang Provincial Department of health(WKJ-ZJ-2137);Key Scientific and Technological Special Project of Ningbo City(2020Z094);the Affiliated Hospital of Medical School of Ningbo University Youth Talent Cultivation Program(FYQM-KY-202002);Furthermore,the authors also acknowledge National Synchrotron Radiation Laboratory in Hefei for High End User Cultivation Fund(2020HSC-UE006);Shanghai Syn-chrotron Radiation Facility at Line BL15U for X-ray fluorescence imaging.
Given that apoptosis increases the risk of plaque rupture, strategies that reduce intracellular lipid levels without killing foam cells are warranted for safe and effective treatment of atherosclerosis. In this study,...