supported by the National Natural Science Foundation of China(21927811,91753111,21907061,62006144);the Key Research and Development Program of Shandong Province(2018YFJH0502);the Postdoctoral Research Foundation of China(2017M622225);Postdoctoral Innovation Foundation of Shandong Province(201703009);Jinan Innovative Team Project(2019GXRC039).
Glioblastoma multiforme(GBM)is the most common and malignant type of primary brain tumor,and 95%of patients die within 2 years after diagnosis.In this study,aiming to overcome chemoresistance to the first-line drug te...