This project has been supported by grants from the National Natural ScienceFoundation of China(32170821 and 92153301 to K.Y.and 32101034 to F.C.);the Ministry of Science and Technologyyof the People's Republic of China(2021YFC2701202);Department of Science&Technology of Hunan Province(2021J10054 and 2019SK1012 to K.Y.,2021J41049 to C.Y.,and the Innovative Team Program 2019RS1010);Central South University(the Innovationdriven Team Project 2020CX016);K.Y.is supported by the National Thousand Talents Program for Young Outstanding Scientists.
Lesions on the DNA template can impact transcription via distinct regulatory pathways.Ionizing radiation(IR)as the mainstay modality for many malignancies elicits most of the cytotoxicity by inducing a variety of DNA ...
the National Natural Science Foundation of China(reference number 31730102);the State Key Basic Research and Development Plan of China(reference number 2015CB150105);the Key Research Plan of Frontier Sciences of the Chinese Academy of Sciences(reference number QYZDJ-SSW-SMC003);the Strategic Priority Research Program of the Chinese Academy of Sciences(reference number XDB17030100);the National Key Scientific Instrument and Equipment Development Project of China(grant no.2013YQ030595).
RNA polymerase transcriptional pausing represents a major checkpoint in transcription in bacteria and metazoans,but it is unknown whether this phenomenon occurs in plant organelles.Here,we report that transcriptional ...