supported by the National Natural Science Foundation of China(No.82172619);the Natural Science Foundation of Chongqing,China(No.CSTC2021jscx-gksb-No023);the Medical and Industrial Integration Project(China)(No.2022CDJYGRH-002).
Protein homeostasis is the basis of normal life activities,and the proteasomefamily plays an extremely important function in this process.The proteasome 2os is a concentric circle structure with twoαrings and twoβri...
the patient for consent to anonymously use his data for publication.Capital Health Development Scientific Research Fund(Grant No.2022-2-4013);National High-Level Hospital Clinical Research Funding(2022-PUMCH-B-048).
Dear Editor,Multiple myeloma(MM)is characterized by the excessive production of monoclonal immunoglobin.As a lot of novel agents were approved during the last two decades,deeper responses and longer survival have been...
Clinical success of the proteasome inhibitor established bortezomib as one of the most effective drugs in treatment of multiple myeloma (MM). While survival benefit of bortezomib generated new treatment strategies, ...
Gastrointestinal stromal tumors (GISTs) are rare tumors, which represent approximately 1% of the neoplasms of the gastrointestinal tract. These tumors rarely give extra-abdominal metastases. However, their clinical ou...