云南高校图书馆联盟文献共享服务平台- ACYL-COA

ACYL-COA: 作品数：24被引量：94H指数：6; 导出分析报告; 相关领域：医药卫生农业科学更多>>; 相关作者：杨璞更多>>; 相关机构：北京大学中国林业科学研究院资源昆虫研究所更多>>; 相关期刊：《International Journal of Ophthalmology(English edition)》《Chinese Medical Journal》《World Journal of Gastrointestinal Pathophysiology》《Open Journal of Pathology》更多>>; 相关基金：国家自然科学基金国家重点基础研究发展计划更多>>

Enhanced triacylglycerol metabolism contributes to the efficient biosynthesis of spinosad in Saccharopolyspora spinosa: 《Synthetic and Systems Biotechnology》2024年第4期809-819,共11页Li Cao Yangchun Liu Lin Sun Zirong Zhu Danlu Yang Ziyuan Xia Duo Jin Zirui Dai Jie Rang Liqiu Xia; supported by funding from the National Natural Science Foundation of China(31770106,32200062);the Natural Science Foundation of Hunan Province(2024JJ5258).; Triacylglycerol(TAG)is crucial for antibiotic biosynthesis derived from Streptomyces,as it serves as an important carbon source.In this study,the supplementation of exogenous TAG led to a 3.92-fold augmentation in spi...; 关键词：Saccharopolyspora spinosa SPINOSAD TRIACYLGLYCEROL LipaseAcyl-CoAs

Enhancing the activity and succinyl-CoA specificity of 3-ketoacyl-CoA thiolase Tfu_0875 through rational binding pocket engineering: 《Synthetic and Systems Biotechnology》2024年第3期558-568,共11页Lixia Liu Shuang Liu Xiangyang Hu Shenghu Zhou Yu Deng; supported by the National Key R&D Program of China(2022YFC2104600);National Natural Science Foundation of China(22378170);the Distinguished Young Scholars of Jiangsu Province(BK20220089);the Tianjin Synthetic Biotechnology Innovation Capacity Improvement Project(TSBICIP-KJGG-015).; The 3-ketoacyl-CoA thiolase is the rate-limiting enzyme for linear dicarboxylic acids production.However,the promiscuous substrate specificity and suboptimal catalytic performance have restricted its application.Here ...; 关键词：Adipic acid 3-Ketoacyl-CoA thiolase Claisen condensation Deep learning GRAPE strategy

Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications: 《Research》2024年第2期105-109,共5页Sha Li Nan Li Jie He Runxin Zhou Zhimin Lu Yizhi Jane Tao Yusong R.Guo Yugang Wang; supported by National Natural Science Foundation of China(91957110,31970577,and 32270642 to Y.W.,32170597 to Y.R.G.)。; Emerging discoveries about undocumented acyltransferase activities of known histone acetyltransferases(HATs)advance our understandings in the regulation of histone modifications.However,the molecular basis of HATs sel...; 关键词：utilize selecting ELECTROSTATIC

Molecular Basis of KAT2A Selecting Acyl-CoA Cofactors for Histone Modifications: 《Research》2023年第4期577-581,共5页Sha Li Nan Li Jie He Runxin Zhou Zhimin Lu Yizhi Jane Tao Yusong R.Guo Yugang Wang; This work was supported by National Natural Science Foundation of China(91957110,31970577,and 32270642 to Y.W.;32170597 to Y.R.G.)。; Emerging discoveries about undocumented acyltransferase activities of known histone acetyltransferases(HATs)advance our understandings in the regulation of histone modifications.However,the molecular basis of HATs sel...; 关键词：utilize selecting ELECTROSTATIC

Acyl-CoA synthase ACSL4:an essential target in ferroptosis and fatty acid metabolism被引量：12: 《Chinese Medical Journal》2023年第21期2521-2537,共17页Kaiyue Ding Chongbin Liu Li Li Ming Yang Na Jiang Shilu Luo Lin Sun; supported by the Key Program of General Program of the National Natural Science Foundation of China(NSFC)(No.81730018);Natural Science Foundation of Hunan Province(No.2021JC0003); Long-chain acyl-coenzyme A(CoA)synthase 4(ACSL4)is an enzyme that esterifies CoA into specific polyunsaturated fatty acids,such as arachidonic acid and adrenic acid.Based on accumulated evidence,the ACSL4-catalyzed bi...; 关键词：Long-chain acyl-coenzyme A(CoA)synthase 4(ACSL4) Ferroptosis Fatty acid metabolism Cancer ISCHEMIA/REPERFUSION Metabolic diseases

Aβ-ketoacyl-CoA Synthase OsCUT1 Confers Increased Drought Tolerance in Rice被引量：1: 《Rice science》2022年第4期353-362,共10页GAO Xiuying ZHANG Ye ZHANG Hongsheng HUANG Ji; the National Natural Science Foundation of China(Grant Nos.32071918 and 32000227).; Drought stress is one of the major environmental factors affecting crop growth and productivity.Cuticular wax plays essential roles in protecting plants from environmental stress via forming a hydrophobic barrier on l...; 关键词：RICE β-ketoacyl-CoA synthase drought tolerance cuticular wax OsCUT1

Structural basis of acyl-CoA transport across the peroxisomal membrane by human ABCD1: 《Cell Research》2022年第2期214-217,共4页Rong Wang Yu Qin Xiaochun Li; We thank Y.Sun and D.Stoddard for assistance in data collection and E.Debler for editing paper.This work was supported by NIH grants P01HL020948,R01GM135343 and Welch Foundation(I-1957)(to X.L.);X.L.is a Damon Runyon-Rachleff Innovator supported by the Damon Runyon Cancer Research Foundation(Grant DRR-53S-19)and a Rita C.and William P.Clements Jr.Scholar in Biomedical Research at UT Southwestern Medical Center.; Dear Editor,ABCD1,a member of the subfamily D of ABC transporters,participates in the transport of various fatty acid-CoA derivatives or very long-chain fatty acids(VLCFA)into the peroxisome and is essential for perox...; 关键词：TRANSPORT METABOLISM HOMEOSTASIS

Diagnosis and treatment of an inborn error of bile acid synthesis type 4:A case report: 《World Journal of Clinical Cases》2021年第26期7923-7929,共7页Shou-Hao Wang Tian-Chen Hui Zhe-Wen Zhou Cheng-An Xu Wen-Hao Wu Qing-Qing Wu Wei Zheng Qiao-Qiao Yin Hong-Ying Pan; BACKGROUND Inborn error of bile acid synthesis type 4 is a peroxisomal disease with impaired bile acid synthesis caused by a-methylacyl-CoA racemase(AMACR)gene mutation.The disease is usually found in children with mi...; 关键词：Bile acid synthesis A-methylacyl-CoA racemase gene Gene mutation Inborn error of metabolism Ursodeoxycholic acid Case report

The group of Jing Wang revealed the dynamic regulation of long chain fatty acyl-CoA esters metabolism in living cells by developing a ratiometric fluorescent Biosensor: 《Journal of Chinese Pharmaceutical Sciences》2021年第4期357-358,共2页无; 近日,北京大学药学院天然药物及仿生药物国家重点实验室王晶团队和华中师范大学化学学院杨光富团队合作在学术期刊《Angewandte Chemie International Edition》发表了题为"A Ratiometric Fluorescent Biosensor Reveals Dynamic Regula...; 关键词：荧光生物传感器动态调控王晶学术期刊团队合作杨光富

Characterization of a broad substrates specificity acyl-CoA:diacylglycerol acyltransferase 1 from the green tide alga Ulva prolifera: 《Acta Oceanologica Sinica》2020年第10期42-49,共8页Xiaowen Zhang Xiaoyuan Chi Yitao Wang Jian Zhang Yan Zhang Dong Xu Xiao Fan Chengwei Liang Naihao Ye; Foundation item:The National Key Research and Development Program of China under contract No.2016YFC1402102;the Central Public-interest Scientific Institution Basal Research Fund,CAFS under contract Nos 2020TD19 and 2020TD27;the Major Scientific and Technological Innovation Project of Shandong Provincial Key Research and Development Program under contract 2019JZZY020706;the International Exchange and Cooperation in Agriculture,Ministry of Agriculture and Rural Affairs of China-Science,Technology and Innovation Cooperation in Aquaculture with Tropical Countries along the Belt and Road;China Agriculture Research System under contract No.CARS-50;the Taishan Scholars Funding and Talent Projects of Distinguished Scientific Scholars in Agriculture;the National Ten Thousand Youth Talents Plan of 2014 under contract No.W02070268.; Triacylglycerols(triglycerides,TAGs)are the major carbon and energy storage forms in various organisms,and important components of cellular membranes and signaling molecules;they have essential functions in multiple p...; 关键词：Ulva prolifera diacylglycerol acyltransferase TRIACYLGLYCEROL stress

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