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作品数:31被引量:151H指数:8
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相关领域:农业科学生物学更多>>
相关作者:王玥孟勐马康郑重陈维信更多>>
相关机构:西南大学河北农业大学华南农业大学北京市结核病胸部肿瘤研究所更多>>
相关期刊:《Chinese Medical Journal》《World Journal of Diabetes》《Science China(Life Sciences)》《Frontiers in Biology》更多>>
相关基金:国家自然科学基金国家重点基础研究发展计划河北省自然科学基金北京市科技新星计划更多>>
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  • 期刊=Cell Researchx
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Plant homeodomain finger protein 2 promotes bone formation by demethylating and activating Runx2 for osteoblast differentiation被引量:8
《Cell Research》2014年第10期1231-1249,共19页Hye-Jin Kim Jong-Wan Park Kyotmg-Hwa Lee Haejin Yoon Dong Hoon Shin Uk-Il Ju Seung Hyeok Seok Seung Hyeon Lim Zang Hee Lee Hong-Hee Kim Yang-Sook Chun 
Plant homeodomain finger protein 2 (PHF2), which contains a plant homeodomain and a Jumonji-C domain, is an epigenetic regulator that demethylates lysine 9 in histone 3 (H3K9me2). On the other hand, runt-related t...
关键词:PHF2 SUV39H1 RUNX2 lysine methylation osteoblast differentiation 
Wnt signaling through T-cell factor phosphorylation被引量:6
《Cell Research》2011年第7期1002-1012,共11页Sergei Y Sokol 
Embryonic signaling pathways often lead to a switch from default repression to transcriptional activation of target genes. A major consequence of Wnt signaling is stabilization of β-catenin, which associates with T-c...
关键词:TCF Wnt PHOSPHORYLATION β-catenin Homeodomain-interacting protein kinase Nemo-like kinase 
Identification of two distinct transactivation domains in the pluripotency sustaining factor nanog被引量:23
《Cell Research》2003年第6期499-502,共4页GUANGJinPAN DUANQINGPEI 
supported in part by the Tsinghua University BaiRen Scholar Program,NSFC 30270287;the 973 Project--2001CB5101 from The Ministry of Science and Technology of China.
Nanog is a newly identified homeodomain gene that functions to sustain the pluripotency of embryonic stem cells.However,the molecular mechanism through which nanog regulates stem cell pluripotency remains unknown.Mous...
关键词:NANOG PLURIPOTENCY stem cells self renewal transactivation domain HOMEOPROTEIN HOMEODOMAIN 
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