EXTENDED-RELEASE

作品数:16被引量:22H指数:3
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相关领域:医药卫生更多>>
相关作者:敖登格日勒陈本川更多>>
相关机构:内蒙古自治区精神卫生中心湖北省医药工业研究院更多>>
相关期刊:《Journal of Pharmaceutical Analysis》《American Journal of Analytical Chemistry》《疾病监测与控制》《Journal of Clinical and Nursing Research》更多>>
相关基金:北京市自然科学基金国家自然科学基金更多>>
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Effect of simultaneous intravitreal ranibizumab and extended-release dexamethasone injection on patients with naïve versus refractory retinal vein occlusion macular edema:a prospective,multicenter,and interventional open-label study
《International Journal of Ophthalmology(English edition)》2025年第5期860-867,共8页Yao-Yao Sun Jie Meng Shan-Shan Li Qin Xiao Tian-Zi Zhang Heng Miao Ming-Wei Zhao Hui-Jun Qi 
Supported by the National Nature Science Foundation of China(No.82301211);Beijing Natural Science Foundation(No.J230028).
AIM:To evaluate the efficacy and safety of concurrent intravitreal ranibizumab(IVR)and extended-release dexamethasone injections(Dex-I)in naïve and refractory patients with retinal vein occlusion macular edema(RVO-ME)...
关键词:retinal vein occlusion macular edema prospective clinical trial anti-vascular endothelial growth factor dexamethasone implant 
Evaluation Study on the Effect of Leuprolide Acetate Extended-Release Microspheres for Injection in Pediatric Precocious Puberty
《Journal of Clinical and Nursing Research》2024年第12期331-336,共6页Huihui Ren Xiaolong Song 
Objective:This study aimed to evaluate the therapeutic effects of leuprolide acetate extended-release microspheres for injection in children with pediatric precocious puberty.Methods:A total of 110 cases of pediatric ...
关键词:Leuprolide acetate Pediatric precocious puberty Sex hormone level Ovarian volume Growth indicators 
Clinical Efficacy of Metoprolol Succinate Extended-Release Tablets in the Treatment of Post-Myocardial Infarction Ventricular Arrhythmias
《Journal of Clinical and Nursing Research》2024年第8期169-174,共6页Hongrun Gao Xiaohua Zhu Lin Guo 
Objective:To investigate the clinical efficacy of metoprolol succinate extended-release tablets in the treatment of post-myocardial infarction ventricular arrhythmias.Methods:The clinical data of 84 patients with post...
关键词:Metoprolol succinate Myocardial infarction Ventricular arrhythmia Clinical efficacy 
治疗人类免疫缺陷病毒Ⅰ型多重耐药性新药——福替沙韦缓释片(fostemsavir extended-release tablets)被引量:2
《医药导报》2021年第3期425-434,共10页陈本川 
人类免疫缺陷病毒(HIV)是侵袭人类免疫系统的病原体。早在20世纪80年代初期,HIV已被美国科学工作者识别,但未引起美国政府重视。至1999年,全球新感染的HIV患者达到最高峰,累计3.16亿例;至2006年,全世界因HIV患者尚无足够有效治疗药物加...
关键词:福替沙韦 Fostemsavir HIV-1融合抑制药 缓释片 前药 
The influence of genetic polymorphisms in drug metabolism enzymes and transporters on the pharmacokinetics of different fluvastatin formulations被引量:1
《Asian Journal of Pharmaceutical Sciences》2020年第2期264-272,共9页Qian Xiang Weidang Wu Nan Zhao Chuan Li Junyu Xu Lingyue Ma Xiaodan Zhang Qiufen Xie Zhuo Zhang Jiancheng Wang Weiren Xu Xia Zhao Yimin Cui 
This study was supported by grants from the National Key R&D Program of China(No.2016YFC0904900);National Natural Science Foundation(No.81673509 and No.81573504)of China;Natural Science Foundation of Beijing Municipality(No.7171012);National Science and Technology Major Projects for“Major New Drugs Innovation and Development”of China(No.2017ZX09304028 and No.2017ZX09101001).
The purpose of the present study was to investigate the impact of genetic polymorphism on fluvastatin pharmacokinetics.In addition,we compared the fluvastatin pharmacokinetics differences between extended-release(ER)8...
关键词:Genetic polymorphisms SLCO1B1 FLUVASTATIN Immediate-release EXTENDED-RELEASE 
Development of Extended-Release Formulation of Ibuprofen Using Blends of Calcium Silicate and Polyvinyl Pyrrolidone as Tablet Matrix
《Journal of Chemistry and Chemical Engineering》2020年第4期119-128,共10页Stephen Olaribigbe Majekodunmi Margaret Ekong Dickson 
A tablet matrix system was developed for ibuprofen and the influence of the polymer blend and concentration on the release rate of the drug was evaluated.Tablets containing different concentrations of calcium silicate...
关键词:Calcium silicate IBUPROFEN ER(extended release) dissolution profile release properties 
Quantitative analysis of 3-isopropylamino-1,2-propanediol as a degradation product of metoprolol in pharmaceutical dosage forms by HILIC-CAD被引量:6
《Journal of Pharmaceutical Analysis》2019年第6期431-436,共6页Qun Xu Shane Tan 
Aryloxypropanolamine is an essential structural scaffold for a variety of b-adrenergic receptor antagonists such as metoprolol.Molecules with such a structural motif tend to degrade into α,β ehydroxypropanolamine im...
关键词:Hydrophilic interaction chromatography(HILIC) Charged aerosol detection(CAD) Metoprolol tartrate injection Metoprolol tartrate tablets Metoprolol succinate extended-release tablets 
Extended tacrolimus release via the combination of lipid-based solid dispersion and HPMC hydrogel matrix tablets被引量:3
《Asian Journal of Pharmaceutical Sciences》2019年第4期445-454,共10页Hui Xu Li Liu Xuehui Li Junyuan Ma Rui Liu Shaoning Wang 
The objective of this study is to evaluate the feasibility of obtaining extended release of tacrolimus by a novel combination of lipid-based solid dispersion and matrix-type extended release tablet techniques. Tacroli...
关键词:TACROLIMUS Solid dispersion Lipid EXTENDED-RELEASE TABLET 
Design and evaluation of an extended-release matrix tablet formulation; the combination of hypromellose acetate succinate and hydroxypropylcellulose被引量:1
《Asian Journal of Pharmaceutical Sciences》2017年第2期149-156,共8页Sachiko Fukui Hideki Yano Shuichi Yada Tsuyoshi Mikkaichi Hidemi Minami 
The purpose of this study was to develop an extended-release(ER) matrix tablet that shows robust dissolution properties able to account for the variability of pH and mechanical stress in the GI tract using a combinati...
关键词:EXTENDED-RELEASE matrix TABLET HYPROMELLOSE ACETATE SUCCINATE HYDROXYPROPYLCELLULOSE Robust dissolution USP apparatus 3 
Evaluation Procedure for Quality Consistency of Generic Nifedipine Extended-Release Tablets Based on the Impurity Profile被引量:1
《American Journal of Analytical Chemistry》2015年第9期776-785,共10页Ming-Yuan Zhang Jun-Dong Zhang Qun Gao Yan Liu Feng Lu 
A procedure to evaluate the quality consistency of generic drugs based on the impurity profile and the similarity analysis methods was presented in this paper. Nifedipine extended-release tablets from six generic fact...
关键词:Impurity Profile CHEMOMETRICS NIFEDIPINE EXTENDED-RELEASE TABLETS Weighting CONSISTENCY EVALUATION 
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