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Theoretical calculation on degradation mechanism of novel copolyesters under CALB enzyme
《Journal of Environmental Sciences》2025年第3期242-253,共12页Yuanyang Ren Zhiwen Cheng Luwei Cheng Yawei Liu Mingyue Li Tao Yuan Zhemin Shen 
supported by the Joint Funds of the National Natural Science Foundation of China(No.U21A20320);the National Natural Science Foundation of China(No.22106102);was also sponsored by the special fund of State Environmental Protection Key Laboratory of Environmental Health Impact Assessment of Emerging Contaminants(No.SEPKLEHIAEC-202203).
Poly(butylene succinate-co-furandicarboxylate)(PBSF)and poly(butylene adipateco-furandicarboxylate)(PBAF)are novel furandicarboxylic acid-based biodegradable copolyesters with great potential to replace fossil-derived...
关键词：Poly(butylene succinate-co-furandicarboxylate) Poly(butylene adipate-co-furandicarboxylate) Candida antarctica lipase B Degradation mechanism Site-directed mutations 
A Self-assembled Nanomicelle for Realizing Tumor Photodynamic Therapy via Increasing Drug Accumulation and Prolonging Retention Time
《高等学校化学学报》2025年第1期106-116,共11页AN Yaolong LI Zi-Heng WU Fu-Gen 
国家自然科学基金(批准号:82372127)资助.
A nanomicelle(denoted as TPGS/Ppa)was fabricated via the coassembly of the amphiphilic D-α-tocopheryl polyethylene glycol 1000 succinate(TPGS)and the hydrophobic photosensitizer pyropheophorbide a(Ppa)for photodynami...
关键词：Photodynamic therapy Nanodrug PHOTOSENSITIZER D-α-Tocopheryl polyethylene glycol 1000 succinate Cell apoptosis 
Three New Hydrogenosuccinate and Succinate Adducts Complexes:Synthesis and Spectroscopic Study
《Journal of Environmental Science and Engineering(A)》2024年第6期207-210,共4页Boucar Diouf Waly Diallo Bocar Traoré Daouda Ndoye Cheikh Abdoul Khadir Diop Mamadou Sidibé 
Plasseraud,ICMUB UMR CNRS 6302,University of Burgundy,Faculty of Sciences,Dijon,France.
One new hydrogenosuccinate and two succinate adduct and complex have been synthesized and studied by infrared,UV-Visible and NMR(Nuclear Magnetic Resonance Spectroscopy)^(119)Sn spectroscopies.The suggested structure ...
关键词：Discrete structures hydrogen bonds monochelating MONODENTATE triangular or trigonal bipyramidal or tetrahedral environments 
Intestinal epithelial cell NCoR deficiency ameliorates obesity and metabolic syndrome
《Acta Pharmaceutica Sinica B》2024年第12期5267-5285,共19页Shaocong Hou Hengcai Yu Caihong Liu Andrew M.F.Johnson Xingfeng Liu Qian Jiang Qijin Zhao Lijuan Kong Yanjun Wan Xiaowei Xing Yibing Chen Jingwen Chen Qing Wu Peng Zhang Changtao Jiang Bing Cui Pingping Li 
supported by grants from the Chinese Academy of Medical Sciences(CAMS)Innovation Fund for Medical Sciences(2021-I2M-1-016,2016-I2M-1-011,2016-I2M-3-008 and 2017-I2M-1-008,China);the Special Research Fund for Central Universities,Peking Union Medical College(3332022047,China);the Beijing Outstanding Young Scientist Program(BJJWZYJH01201910023028,China);the National Natural Science Foundation of China(81703588,82473984,81622010,81770800,and 81874316);the CAMS Central Public-interest Scientific Institution Basal Research Fund(2017RC31009 and 2018PT35004,China);the Drug Innovation Major Project from the National Science and Technology Department(2018ZX09711001-003-005 and 2018ZX09711001-003-001,China);the National Key R&D Program of China(2017YFA0205400 and 2022YFC2505204,China).
Nuclear receptor corepressor(NCoR1)interacts with various nuclear receptors and regulates the anabolism and catabolism of lipids.An imbalance in lipid/energy homeostasis is also an important factor in obesity and meta...
关键词：Nuclear receptor co-repressor 1 Intestinal epithelium Metabolic syndrome PPAR alpha Liver X receptor THERMOGENESIS SUCCINATE CHOLESTEROL 
Molecular activation and G protein coupling selectivity of human succinate receptor SUCR1
《Cell Research》2024年第8期590-593,共4页Tianxin Wang Wenqin Tang Xiaolei Zhu Zhenyu Lv Jiayan Chen Yongze Li Xiaoyu Sun Haoyu Lv Quanchang Gu Fahui Li Jiangyun Wang 
support from the National Natural Science Foundation of China(22121003,22337006,32027901 and 21927814);the National Key R&D Program of China(2019YFA0904201,2023YFA0916300,2021YFA0910202 and 2022YFA1304701);the Strategic Priority Research Program of Chinese Academy of Sciences(XDB37040203);the CAS Project for Young Scientists in Basic Research(YSBR-015 and YSBR-072-6).
Dear Editor,Succinate(SA)is a classic intermediate metabolite of the TCA cycle and is produced in mitochondria under normal physiological conditions.1 SA accumulates within cells and is secreted into the extracellular...
关键词：CR1 HOMEOSTASIS INFLAMMATION 
Molecular basis of ligand recognition and activation of the human succinate receptor SUCR1
《Cell Research》2024年第8期594-596,共3页Changyao Li Heng Liu Jingru Li Xinheng He Haoran Zhu Wei Fu H.Eric Xu 
supported by grants from CAS Strategic Priority Research Program(XDB37030103 to H.E.X.);Shanghai Municipal Science and Technology Major Project(2019SHZDZX02 to H.E.X.);Shanghai Municipal Science and Technology Major Project(H.E.X.);the National Natural Science Foundation of China(32130022,82121005);the Lingang Laboratory(LG-GG-202204-01 to H.E.X.);the National Key R&D Program of China(2022YFC2703105 to H.E.X.)。
Dear Editor,Succinic acid,once considered merely a tricarboxylic acid cycle intermediate,1 has been recognized for its significant role in influencing mitochondrial reactive oxygen species homeostasis.2 This is largel...
关键词：CR1 ACTIVATION connecting 
Analysis and Characterization of the GABA Transaminase and Succinate Semialdehyde Dehydrogenase Genes in the Microalga Isochrysis zhanjiangensis in Response to Abiotic Stresses
《Journal of Ocean University of China》2024年第3期775-785,共11页TIAN Jiaojiao ZHANG Lin LU Xinyue YE Lingzhi WU Yuanyuan CHEN Deshui CAO Jiayi JIANG Jiaxin XU Jilin YAN Xiaojun 
supported by the Zhejiang Provincial Natural Science Foundation of China(No.LY22C190001);the Natural Science Foundation of Ningbo Government(No.2021J114);the Ningbo Science and Technology Research Projects,China(No.2019B10006);the Zhejiang Provincial Department of Education Scientific Research Project(No.Y202249030);the Earmarked Fund for CARS-49;partly sponsored by K.C.Wong Magna Fund in Ningbo University.
Gamma-aminobutyric acid(GABA),widely existing in different organisms,is rapidly accumulated in plants in response to environmental stresses.The main biosynthesis and degradation pathways of GABA constitute the GABA sh...
关键词：abiotic stress GABA heterologous expression Isochrysis zhanjiangensis TRANSCRIPTION 
Prevotella and succinate treatments altered gut microbiota,increased laying performance,and suppressed hepatic lipid accumulation in laying hens
《Journal of Animal Science and Biotechnology》2024年第2期844-861,共18页Min Liu Zeyue Kang Xikang Cao Hongchao Jiao Xiaojuan Wang Jingpeng Zhao Hai Lin 
supported by grants from the National Natural Science Foundation of China(32330101,32102575);National Key Research and Development Program of China(2021YFD1300405);Modern Agro-industry Technology Research System(CARS-40-K9);the Key Technology Research and Development Program of Shandong province(2019JZZY020602);Shandong Provincial Natural Science Foundation(ZR2020QC180);China Postdoctoral Science Foundation(2019M660163).
Background This work aimed to investigate the potential benefits of administering Prevotella and its primary metabolite succinate on performance,hepatic lipid accumulation and gut microbiota in laying hens.Results One...
关键词：Fatty liver Gut microbiota Laying hen PREVOTELLA SUCCINATE 
Effect of sodium starch octenyl succinate-based Pickering emulsion on the physicochemical properties of hairtail myofibrillar protein gel subjected to multiple freeze-thaw cycles被引量：1
《Food Science and Human Wellness》2024年第2期1018-1028,共11页Huinan Wang Jiaxin Zhang Xinran Liu Jinxiang Wang Xuepeng Li Jianrong Li 
supported by the National Natural Science Foundation of China(U20A2067,32272360)。
A Pickering emulsion based on sodium starch octenyl succinate(SSOS)was prepared and its effects on the physicochemical properties of hairtail myofibrillar protein gels(MPGs)subjected to multiple freeze-thaw(F-T)cycles...
关键词：Pickering emulsion Myofibrillar protein Gel properties Freeze-thaw stability Intermolecular interactions 
Insight into the green route to dimethyl succinate by direct esterification of bio-based disodium succinate using CO_(2)and CH_(3)OH
《Chinese Journal of Chemical Engineering》2023年第12期188-195,共8页Yu-Gao Wang Xiao-Chen Han Bao Gu Hua-Shuai Wu Jun Shen 
Natural Science Foundation of Shanxi Province(202203021221069 and 202103021223063);National Natural Science Foundation of China(21706172).
The fermentation for succinic acid production outperforms other methods by low energy consumption and environmental benignity,with the resulting products mainly as disodium succinate(DSA).By directly esterifying DSA u...
关键词：SUCCINATE Carbon dioxide Direct esterification Reaction mechanism Reaction kinetics Kinetic modeling 
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