PYRAZOLOPYRIDINE

作品数:5被引量:3H指数:1
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相关期刊:《Science China Chemistry》《Chinese Journal of Structural Chemistry》《International Journal of Organic Chemistry》《Open Journal of Medicinal Chemistry》更多>>
相关基金:国家自然科学基金江苏省重点实验室开放基金更多>>
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Docking Studies, Synthesis, and Evaluation of Antioxidant Activities of N-Alkylated, 1,2,4-Triazole, 1,3,4-Oxa-, and Thiadiazole Containing the Aminopyrazolopyridine Derivatives被引量:1
《International Journal of Organic Chemistry》2013年第3期198-205,共8页Yasser K. Abdelmonem Farag A. El-Essawy Saeda A. Abou El-Enein Mona M. El-Sheikh-Amer 
Synthesis of some 1,3,4-thia-, oxa-diazol and 1,2,4 triazole incorporated the biologically active and the pyrazolopyri-dine derivative. Molecular modeling and docking of the active compounds into AKR1C3 complexed with...
关键词:PYRAZOLOPYRIDINE Biologically Active Molecular Modeling and INHIBITOR 
Novel 2H-pyrazolo[4,3-c]hexahydropyridine derivatives: Synthesis, crystal structure, fluorescence properties and cytotoxicity evaluation against human breast cancer cells被引量:1
《Science China Chemistry》2013年第6期702-715,共14页PANG ChunCheng SUN ChuanWen WANG Jing XIAO Di DING Li BU HongFei 
supported by Zooblast-molecular Biology Laboratory of Shanghai Normal University;supported by the National Natural Science Foundation of China (21042010, 21102092 and30870560);the Key Scientific "Twelfth Five-Year" National Technology Support Program (2011BAE06B01-17);the Innovation Project of Shanghai Education Commission (12YZ078);the Key Project of the Science and Technology Commission of Shanghai 105405503400);the Leading Academic Discipline Project of Shanghai Normal University (DZL808);Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Normal University (07dz22303)
A series of novel 2H-pyrazolo[4,3-c]hexahydropyridine derivatives (II) have been designed and synthesized. The target com- pounds have been identified by elemental analysis and spectral (1H NMR, IR, and MS) data a...
关键词:PYRAZOLOPYRIDINE SYNTHESIS crystal structure breast cancer cells cytotoxicity evaluation apoptosis fluorescence prop-erties 
Design, Synthesis and Cancer Cell Line Activities of Pyrazolo[3,4-<i>b</i>]pyridine Derivatives
《Open Journal of Medicinal Chemistry》2012年第3期78-88,共11页Mosaad Sayed Mohamed Yara Essam El-Deen Awad Salwa M. El-Hallouty Moustafa El-Araby 
Starting from 4,6-dimethyl-2-oxo-(1H)-3-pyridinecarbonitrile 1 and 3-aminopyrazolopyridine 4, a series of cyanopyri- dine derivatives 3a-i, Schiff bases 5a-f, urea and thiourea derivatives 6a-b, amide derivatives 7a-h...
关键词:PYRIDINE PYRAZOLOPYRIDINE ANTICANCER Activity CDK Inhibitors Kinase Inhibitor 
Synthesis and Crystal Structure of 1-Phenyl-3-methyl-4-(4-bromophenyl)-6-(2-chlorophenyl)pyrazolo[3,4-b] Pyridine under Microwave Irradiation被引量:1
《Chinese Journal of Structural Chemistry》2005年第1期6-6,共1页邹翔  屠树江  朱松磊  纪顺俊  张勇  
国家自然科学基金,江苏省自然科学基金,江苏省重点实验室基金,江苏省重点实验室基金
The title compound (C25H17BrClN3) has been synthesized by the reaction of 1-(2- chlorophenyl)-3-(4-bromophenyl)-2-propylene-1-one with 5-amino-3-methyl-1-phenyl pyrazole under microwave irradiation and its structure...
关键词:AMINOPYRAZOLE PYRAZOLOPYRIDINE crystal structure microwave irradiation 
Synthesis and Crystal Structure of 4-(2- Chlorophenyl)-5-cyano-3-methyl-6-oxo-1- phenyl-4,5,6,7-tetrahydropyrazolo[3,4-b] Pyridine under Microwave Irradiation
《Chinese Journal of Structural Chemistry》2004年第11期1222-1225,共4页朱松磊  屠树江  李团结  邹翔  章晓镜  纪顺俊  张勇  
This work was supported by the NNSFC (No. 20372057); the NSF of Jiangsu Province (No. BK2001142); the Open Foundation of Key Laboratory of Organic Synthesis of Jiangsu Province; College of Chemistry and Chemical Engineering; Suzhou University (No. S
The title compound (C20H15ClN4O, Mr = 362.81) was synthesized by the reaction of ethyl 2-cyano-3-(2-chlorophenyl)-1-acylate with 5-amino-3-methyl-1-phenylpyrazole under microwave irradiation and its structure was dete...
关键词:AMINOPYRAZOLE PYRAZOLOPYRIDINE crystal structure microwave irradiation 
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