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Synthesis of some 1,3,4-thia-, oxa-diazol and 1,2,4 triazole incorporated the biologically active and the pyrazolopyri-dine derivative. Molecular modeling and docking of the active compounds into AKR1C3 complexed with...
supported by Zooblast-molecular Biology Laboratory of Shanghai Normal University;supported by the National Natural Science Foundation of China (21042010, 21102092 and30870560);the Key Scientific "Twelfth Five-Year" National Technology Support Program (2011BAE06B01-17);the Innovation Project of Shanghai Education Commission (12YZ078);the Key Project of the Science and Technology Commission of Shanghai 105405503400);the Leading Academic Discipline Project of Shanghai Normal University (DZL808);Shanghai Key Laboratory of Rare Earth Functional Materials, Shanghai Normal University (07dz22303)
A series of novel 2H-pyrazolo[4,3-c]hexahydropyridine derivatives (II) have been designed and synthesized. The target com- pounds have been identified by elemental analysis and spectral (1H NMR, IR, and MS) data a...
Starting from 4,6-dimethyl-2-oxo-(1H)-3-pyridinecarbonitrile 1 and 3-aminopyrazolopyridine 4, a series of cyanopyri- dine derivatives 3a-i, Schiff bases 5a-f, urea and thiourea derivatives 6a-b, amide derivatives 7a-h...
The title compound (C25H17BrClN3) has been synthesized by the reaction of 1-(2- chlorophenyl)-3-(4-bromophenyl)-2-propylene-1-one with 5-amino-3-methyl-1-phenyl pyrazole under microwave irradiation and its structure...
This work was supported by the NNSFC (No. 20372057); the NSF of Jiangsu Province (No. BK2001142); the Open Foundation of Key Laboratory of Organic Synthesis of Jiangsu Province; College of Chemistry and Chemical Engineering; Suzhou University (No. S
The title compound (C20H15ClN4O, Mr = 362.81) was synthesized by the reaction of ethyl 2-cyano-3-(2-chlorophenyl)-1-acylate with 5-amino-3-methyl-1-phenylpyrazole under microwave irradiation and its structure was dete...