ELASTASE

作品数：50被引量：98H指数：5
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相关领域：医药卫生更多>>
相关作者：刘震杰朱立新范上达耿小平杨光更多>>
相关机构：第二军医大学浙江大学医学院附属第二医院上海交通大学附属第六人民医院西北农林科技大学更多>>
相关期刊：《外科研究与新技术（中英文）》《中国循环杂志》《Journal of Hainan Medical University》《Bioactive Materials》更多>>
相关基金：国家自然科学基金中国科学院科研项目北京市自然科学基金国家重点基础研究发展计划更多>>
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In vitro and in silico approach for the evaluation of enzyme inhibitory potential of Kadipatta (Murraya koenigii) collected from western Nepal
《Clinical Traditional Medicine and Pharmacology》2024年第4期44-53,共10页Suman Prakash Pradhan Ishan Subedi Kapil Adhikari Ashok GC Sujan Prakash Pradhan Mukti Ram Aryal Gopal Prasad Ghimire Bishnu Prasad Pandey 
supported by a UGC collaborative research grant(Award No:CRG-78/79-S&T-01)and also supported by H-Plant Nepal Private Limited.
Background:Murraya koenigii(L.)Spreng.(Rutaceae)is an evergreen shrub distributed over the sub-tropical to lower temperate climatic zone of Nepal which has been used as spice in culinary practice and traditionally bei...
关键词：Murraya koenigii 𝛼α-amylase LIPASE ELASTASE TYROSINASE Cholinesrerase 
The incidence rate and histological characteristics of intimal hyperplasia in elastase-induced experimental abdominal aortic aneurysms in mice
《Animal Models and Experimental Medicine》2024年第3期388-395,共8页Meng Li Panpan Wei Kexin Li Haole Liu Naqash Alam Haiwen Hou Jie Deng Baohui Xu Enqi Liu Sihai Zhao Yankui Li 
supported by Shaanxi Provincial Natural Science Foundation(2023-CX-PT-17 to Sihai Zhao);Natural Science Foundation of Xi'an Jiaotong University Foundation(YXJLRH2022073 to Sihai Zhao);Project of Key Laboratory of Medical Large Animal Models of Guangdong Province(Klmlam 202204 to Sihai Zhao)。
Intimal hyperplasia(IH)is a negative vascular remodeling after arterial injury.IH occasionally occurs in elastase-induced abdominal aortic aneurysm(AAA)mouse models.This study aims to clarify the incidence and histolo...
关键词：abdominal aortic aneurysms animal model HISTOLOGY intimal hyperplasia 
Targeted PERK inhibition with biomimetic nanoclusters confers preventative and interventional benefits to elastase-induced abdominal aortic aneurysms
《Bioactive Materials》2023年第8期52-63,共12页Nisakorn Yodsanit Takuro Shirasu Yitao Huang Li Yin Zain Husain Islam Alexander Christopher Gregg Alessandra Marie Riccio Runze Tang Eric William Kent Yuyuan Wang Ruosen Xie Yi Zhao Mingzhou Ye Jingcheng Zhu Yi Huang Nicholas Hoyt Mengxue Zhang John A.Hossack Morgan Salmon K.Craig Kent Lian-Wang Guo Shaoqin Gong Bowen Wang 
supported by the National Institute of Health(NIH)grants R01HL133665(to L.-W.G.),R01HL143469;R01HL129785(to K.C.K,S.G.,and L.-W.G.);R01HL162895(to B.W.);R01HL132395 and 1S10RR027333(to J.A.H.);Overseas Research Fellowships,The Uehara Memorial Foundation in Japan(to T.S.).
Abdominal aortic aneurysm(AAA)is a progressive aortic dilatation,causing~80%mortality upon rupture.Currently,there is no approved drug therapy for AAA.Surgical repairs are invasive and risky and thus not recommended t...
关键词：Abdominal aortic aneurysm ER stress PERK Biomimetic nanomedicine Targeted delivery 
Potential Application of a Wine Extract in Skin Care: How to Benefit from the Antibacterial, Antioxidant and Elastase Inhibiting Properties
《Journal of Cosmetics, Dermatological Sciences and Applications》2023年第2期136-155,共20页Lisa-Marie Sittek Thomas Michael Schmidts Peggy Schlupp 
Since plant polyphenols have many beneficial properties on health, the aim of this study was to evaluate the potential use of a phenolic wine extract, a by-product of wine production, for skin care on HaCaT cells. In ...
关键词：Phenolic Wine Extract Skin Care HaCaT Cells ELASTASE LIPASE IL-6 IL-8 Cell Proliferation Reactive Oxygen Species Antimicrobial ANTIMYCOTIC 
Interference in the production of bacterial virulence factors by olive oil processing waste
《Food Bioscience》2022年第5期1144-1155,共12页Carolina María Viola Romina Torres-Carro María Cecilia Verni Eliana del Valle Leal Stefano Dall’Acqua Francisca Rodrigues Elena Cartagena María Rosa Alberto Mario Eduardo Arena 
the financial support from the SCAIT-UNT(PIUNT D26/638-1);the Agencia Nacional de Promocion Científica y Tecnica ANPCyT(PICT 02071 and 02514);The Consejo Nacional de Investigaciones Científicas y Tecnicas,CONICET(PIP 662,PUE 0021).The authors also acknowledge the Camara olivícola Riojana(La Rioja,Argentina)for providing the alperujo.
The reuse of agricultural waste is essential to mitigate environmental pollution problems.Consequently,this work focused on the valorization of the most extensive olive processing residue,alperujo,in terms of its abil...
关键词：Alperujo BIOFILM MOTILITY Quorum sensing Phenolic compounds ELASTASE 
Kunming mouse strain is less susceptible to elastase-induced abdominal aortic aneurysms被引量：3
《Animal Models and Experimental Medicine》2022年第1期72-80,共9页Haole Liu Kangli Tian Congcong Xia Panpan Wei Boyu Xu Weilai Fu Yankui Li Yafeng Li Liang Bai Rong Wang Weirong Wang Baohui Xu Enqi Liu Sihai Zhao 
partly supported by grants from the Natural Science Foundation of Shaanxi Province (2020PT-004, 2017BSHQYXMZZ18 and 2021PT-056);the National Natural Science Foundation of China (82070470 and 81370379)
Background:Porcine pancreatic elastase(PPE)is successfully used to induce abdominal aortic aneurysm(AAA)in mice.However,differences between mouse strains in susceptibility to PPE induction have been reported.Kunming m...
关键词：abdominal aortic aneurysms C57BL/6J HISTOLOGY Kunming STRAIN 
Histidine ameliorates elastase-and lipopolysaccharide-induced lung inflammation by inhibiting the activation of the NLRP3 inflammasome被引量：4
《Acta Biochimica et Biophysica Sinica》2021年第8期1055-1064,共10页Qiaoshan Tian Ming Xu Bei He 
supported by the grants from the National Natural Science Foundation of China(Nos.81670034 and 81470235).
Histidine treatment has anti-inflammatory effects on several diseases such as colitis and obesity.We revealed that histidine levels were decreased in the serum of patients with chronic obstructive pulmonary disease(CO...
关键词：HISTIDINE COPD inflammation NLRP3 SIRT1 
Elastase作为靶点在铜绿假单胞菌眼科感染治疗中的研究进展
《眼科学报》2020年第3期186-191,共6页李晔 胡沁媛 周敏 王聪尧 李健(综述) 万鹏霞(审校) 
国家药监局合作课题(K0601300);广东省药学会基金(2019QX16)。
铜绿假单胞菌性角膜炎破坏力强、致盲率高。随着“后抗生素时代”的到来,新的抗铜绿假单胞菌感染药物的研究迫在眉睫。抗毒力因子药物可选择性地遏制细菌的毒素表达、细菌黏附和免疫逃避,在不影响细菌生长的前提下可降低细菌的毒性,具...
关键词：弹性蛋白酶 铜绿假单胞杆菌 毒力因子 
Which factors determine exocrine pancreatic dysfunction in diabetes mellitus?被引量：9
《World Journal of Gastroenterology》2019年第22期2699-2705,共7页Mustafa Altay 
The exocrine structure is significantly affected by diabetes because of endocrine structure-function disorder within the pancreas. Exocrine pancreatic dysfunction (EPD) is the general name of the malabsorption process...
关键词：EXOCRINE PANCREAS Diabetes MELLITUS FECAL ELASTASE MALABSORPTION Chronic complication 
Effects of the Syzygium aromaticum L. extract on antioxidation and inhibition of matrix metalloproteinase in human dermal fibroblast被引量：1
《Asian Pacific Journal of Tropical Biomedicine》2019年第2期53-59,共7页Da Eun Kim Yeon Sil Hwang Bo Yoon Chang Dae Sung Kim Hyoung Kwon Cho Sung Yeon Kim 
supported by Wonkwang University in 2018
Objective: To investigate cosmetic potential of Syzygium aromaticum L.(S. aromaticum L.) and to determine its antioxidant and anti-wrinkling effects. Methods: Using highperformance liquid chromatography, eugenol compo...
关键词：SYZYGIUM aromaticum L Antioxidant ANTI-AGING ELASTASE Matrix metalloproteinase-1 
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