supported by the National Natural Science Foundation of China(82293684 and 82293680);the National Key R&D Program of China(2020YFA0908004);CAMS Innovation Fund for Medical Science of China(2022-I2M-1-014).
Interleukin-1 receptor-related kinase(IRAK4)is a widely expressed serine/threonine kinase involved in the regulation of innate immunity.IRAK4 plays a pivotal role as a key kinase within the downstream signaling pathwa...
Macrophages,existed in almost all organs of the body,are responsible for detecting tissue injury,pathogens,playing a key role in host defense against a variety of invading pathogens triggering inflammatory responses.E...