相关期刊:《International Journal of Biomathematics》《Journal of Applied Mathematics and Physics》《Acta Biochimica et Biophysica Sinica》《Science China(Life Sciences)》更多>>
supported by the National Natural Science Foundation of China under No. 52177217;the Postdoctoral Innovative Talents Support Program under No. BX20240232。
Cell-to-cell variations(CtCV) compromise the electrochemical performance of battery packs, yet the evolutional mechanism and quantitative impacts of CtCV on the pack's fast-charging performance remain unexplored. This...
This work was supported by the National Natural Science Foundation of China(#11701445);the Natural Science Basic Research Program in Shaanxi Province of China(2022JM-042,2022JM-038,2022JQ-033,2020JQ-831,2022JQ-043).
A new viral infection model with cell-to-cell infection and periodic antiretroviral therapy was proposed and analyzed.With the help of defined basic reproduction number Ro,we proved that if R_(0)<1,then the infection-...
supported in part by the National Key Basic Research and Development Program of China(2019YFA0801402,2018YFA0107200,2018YFA0801402,2018YFA0800100);the Major Project of Guangzhou National Laboratory(GZNL2023A02005);the Strategic Priority Research Program of the Chinese Academy of Sciences(XDA16020501,XDA16020404);the National Natural Science Foundation of China(32130030,31900454).
Mammalian lung development starts from a specific cluster of endodermal cells situated within the ventral foregut region.With the orchestrating of delicate choreography of transcription factors,signaling pathways,and ...
the National Natural Science Foundation of China(No.12171413);Natural Science Foundation of Henan Province(222300420016);the Program for Innovative Research Team(in Science and Technology)in Universities of Henan Province(21IRTSTHN014);the National Science Foundation Grants DMS-1950254 and DMS-2324692.
This paper develops a mathematical model to investigate the Human Immunodeficiency Virus(HIV)infection dynamics.The model includes two transmission modes(cell-to-cell and cell-free),two adaptive immune responses(cytot...
supported by the Michael J.Fox Foundation for Parkinson’s Research(MJFF)grant 16879(M.X.H)and Aligning Science Across Parkinson’s ASAP-020616 through MJFF;NIH grants:R01-AG077573(D.S.B,M.X.H.);NSF grants PHY-1554488(D.S.B)and BCS-1631550(D.S.B).D.S.B.also acknowledges support from the John D.and Catherine T.MacArthur Foundation,the ISI Foundation,the Alfred P.Sloan Foundation,and the Paul G.Allen Foundation.
Background Mutations in leucine-rich repeat kinase 2(LRRK2)are the most common cause of familial Parkinson’s disease(PD).These mutations elevate the LRRK2 kinase activity,making LRRK2 kinase inhibitors an attractive ...
supported by the grants from the Ministry of Science and Technology of China (Nos.2019YFA0802103 and 2021ZD0203900);the Department of Science and Technology of Zhejiang Province (No.2021C03104);the Guangzhou Science Innovation and Development Program (No.201803010092);the Shenzhen-Hong Kong Institute of Brain Science (No.NYKFKT2019006);the National Natural Science Foundation of China (No.92253302).
Severe acute respiratory syndrome coronavirus 2(SARS-CoV-2),responsible for the COVID-19 pandemic,has caused tremendous global loss and continues to evolve to generate variants.Entry of SARS-CoV-2 into target host cel...
MSCs are pluripotent stem cells which have multipotent differentiation potential and immunosuppressive ability.Therefore,MSCs play an important role in regenerative medicine;the study of their mechanisms of regulating...
funded by an industry-academia collaborative grant EPSRC EP/R511687/1 awarded by Engineering and Physical Sciences Research Council(EPSRC)&University of Edinburgh United Kingdom program Impact Acceleration Account(IAA).G.dos Reis acknowledges support from the Fundaçao para a Ciencia e a Tecnologia(Portuguese Foundation for Science and Technology)Portugal through the project UIDB/00297/2020 and UIDP/00297/2020(Center for Mathematics and Applications,CMA/FCT/UNL Portugal);P.Dechent was supported by Bundesministerium für Bildung und Forschung Germany(BMBF 03XP0302C).
The testing of battery cells is a long and expensive process, and hence understanding how large a test set needsto be is very useful. This work proposes an automated methodology to estimate the smallest sample size of...
This work was supported by the National Science Foundation of China(No.82071788);Three-year Action Plan for Shenkang Clinical Research from Shanghai Municipal Health Commission(SHDC2020CR3011A);the Special Medical Innovation Research Project of“Scientific and Technological Innovation Action Plan”of Shanghai Municipal Commission of Science and Technology in 2020(20Y11900500).
Background:Interferon kappa(IFN-k)is a type I interferon(IFN-I)that inhibits virus replication by evoking interferon-stimulated genes(ISGs).However,as an evolutionarily ancient interferon,IFN-k may function differentl...
Wang is supported by the NSFC(Nos.11771374,12026204 and 12171413);the Program for Science and Technology Innovation Teams in Henan(21IRTSTHN014);Rong is supported by the NSF grants DMS-1758290 and DMS-1950254.
In this paper,we propose a reaction–diffusion viral infection model with nonlinear incidences,cell-to-cell transmission,and a time delay.We impose the homogeneous Neumann boundary condition.For the case where the dom...