ISODON

作品数：55被引量：44H指数：3
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相关领域：医药卫生生物学更多>>
相关作者：孙汉董纳智姜北李朝明牛雪梅更多>>
相关机构：中国科学院广州中医药大学广西师范大学大理医学院更多>>
相关期刊：《Chinese Journal of Natural Medicines》《Science China Chemistry》《Plant Diversity》《中山大学研究生学刊（自然科学与医学版）》更多>>
相关基金：国家自然科学基金河北省自然科学基金中国科学院知识创新工程国家重点基础研究发展计划更多>>
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Material Basis and Mechanism for Anti-tumor Efficacy of Isodon suzhouensis Roots Based on UPLC-Q-TOF-MS/MS and Network Pharmacology
《Agricultural Biotechnology》2024年第6期69-77,共9页Meihui DUAN Meiqi WEI Weixian YANG Weiqing ZHANG Xianji LIU Chen YAN 
[Objectives]This study was conducted to explore the anti-tumor substances and mechanism of Isodon suzhouensis roots based on high performance liquid chromatography-quadrupole-time-of-flight mass spectrometry(UPLC-Q-TO...
关键词：Isodon suzhouensis roots Antitumor effect UPLC-Q-TOF-MS/MS Network pharmacology Molecular docking 
The potential mechanism of Isodon suzhouensis against COVID-19 via EGFR/TLR4 pathways
《Food Science and Human Wellness》2024年第6期3245-3255,共11页Hong Duan Wei Wang Shu Li Han Li Ghulam Jilany Khan Yong Ma Fawang Liu Kefeng Zhai Henggui Hu Zhaojun Wei 
supported by the National Natural Science Foundation of China(82170481);Anhui Natural Science Foundation(2008085J39 and 2108085MH314);Excellent Top-notch Talents Training Program of Anhui Universities(gxbjZD2022073);Anhui Province Innovation Team of Authentic Medicinal Materials Development and High Value Utilization(2022AH010080);Suzhou University Joint Cultivation Postgraduate Research Innovation Fund Project(2023KYCX04).
Corona Virus Disease 2019(COVID-19)has brought the new challenges to scientific research.Isodon suzhouensis has good anti-inflammatory and antioxidant stress effects,which is considered as a potential treatment for CO...
关键词：Isodon suzhouensis COVID-19 Network pharmacology TLR4/NF-κB pathway Epidermal growth factor receptor PI3K/Akt pathway 
Selenium Regulates Antioxidant Capacities and Diterpenoid Biosynthesis in the Medicinal Plant Isodon rubescens
《Phyton-International Journal of Experimental Botany》2024年第7期1705-1716,共12页Fenglan Zhao Shuwen Wu Xue Meng Jianping Xue Yongbo Duan 
supported by the Key Project of Natural Science Research for Colleges and Universities in Anhui Province(2023AH050345,KJ2021A0533);the Excellent Scientific Research and Innovation Team of Universities in Anhui Province(2022AH010029).
Dōng líng căo,the dried aboveground parts of Isodon rubescens(Hemls.)Hara.,is commonly consumed as a med-icinal decoction or tea beverage.Natural beverages can be an important source of human dietary selenium(Se).Ho...
关键词：FLAVONOIDS ORIDONIN physiological indicators quantitative real-time PCR SELENIUM 
Study on the Action Mechanism of Isodon suzhouensis Stems in the Treatment of Prostate Cancer Based on UPLC-Q-TOF-MS/MS Combined with Network Pharmacology and Molecular Docking
《Agricultural Biotechnology》2023年第5期91-97,共7页Peigui LIU Weiqing ZHANG Xianji LIU Meihui DUAN Weixian YANG Meiqi WEI 
Supported by Science and Technology Project of Guizhou Provincial Health Commission(gzwkj2021-364);Social Development Project of Anshun City Science and Technology Bureau in 2022(ASKS[2022]39);Social Development Project of Anshun City Science and Technology Bureau in 2021(ASKS[2021]41).
[Objectives]This study was conducted to explore the action mechanism of chemical components from stems of Isodon suzhouensis on prostate cancer based on UPLC-Q-TOF-MS/MS technique,network pharmacology,and molecular do...
关键词：Stem of Isodon suzhouensis UPLC-Q-TOF-MS/MS Network pharmacology Molecular docking Prostatic cancer 
Flavidanolides A and B from Isodon flavidus
《Chinese Chemical Letters》2023年第9期160-164,共5页Jiang-Hai Ye Guo-Yong Luo Chen-Liang Zhao Zheng-Ming Liang Jin-Huai Wei Ya-Hua Liu Kang He Lu-Tai Pan Jing-Jie Zhang Juan Zou Hong-Jie Zhang 
supported by the National Natural Science Foundation of China(No.82204605);the National Natural Science Foundation of China(No.81560709);the Technology Fund of Guizhou Administration of Traditional Chinese Medicine(No.QZYY-2022019);Science and Technology Tip-top Talent Foundation of Universities in Guizhou Province(No.Qian jiao he KY(2021)034);the Research Grant Council of the Hong Kong Special Administrative Region,China(No.HKBU 12102219);the University Grants Committee of the Hong Kong Special Administrative Region,China(UGC Research Matching Grant Scheme,No.RMG2019_1_19)。
A phytochemical investigation on Isodon flavidus led to the isolation of flavidanolide A(1),a rearranged diterpenoid featuring a six/seven/five-membered tricyclic skeleton,together with flavidanolide B(2),an uncommon ...
关键词：Isodon flavidus Rearranged six/seven/five-membered SKELETON Heterodimeric diterpenoid Plausible biosynthetic pathway Antiinflammatory effects 
A chromosome-level genome assembly reveals that tandem-duplicated CYP706V oxidase genes control oridonin biosynthesis in the shoot apex of Isodon rubescens被引量：4
《Molecular Plant》2023年第3期517-532,共16页Yuwei Sun Jie Shao Haili Liu Hua Wang Guangyi Wang Jianhua Li Yaping Mao Zhuo Chen Ke Ma Lin Xu Yong Wang 
funded by the National Key R&D Program of China(2018YFA0900600);the National Natural Science Foundation of China(32070328,22077129,and 41876084),the Program of Shanghai Academic Research Leader(20XD1404400);the Strategic Priority Research Program“Molecular Mechanism of Plant Growth and Development”of CAS(XDB27020202);the Construction of the Registry and Database of Bioparts for Synthetic Biology of the Chinese Academy of Sciences(ZSYS-016),the International Partnership Program of the Chinese Academy of Sciences(153D31KYSB20170121),Derivative Bank of Chinese Biological Resources(KFJ-BRP-009-002);the National Key Laboratory of Plant Molecular Genetics,SIPPE,CAS.Y.S.is supported by the Foundation of Youth Innovation Promotion Association of the Chinese Academy of Sciences.
The ent-kaurenoids(e.g.,oridonin and enmein)from the Isodon genus(Lamiaceae)are one class of diterpenoids with rich structural diversity and intriguing pharmaceutical activity.In contrast to the well-established gibbe...
关键词：oridonin biosynthesis Isodon rubescens genome sequencing CYP706 oxidases diterpenoid diversity 
Network pharmacology-based strategy to investigate harmacological mechanisms of Isodon serra(Maxim.)Hara for treatment of inflammatory被引量：2
《Journal of Chinese Pharmaceutical Sciences》2022年第4期250-263,共14页Weiwei Xie Xuqing Wen Dedong Zhang Yuqian Zhang Zhiqing Zhang Yiran Jin Yingfeng Du 
Hebei Administration of Traditional Chinese Medicine(Grant No.2021133);the Natural Science Foundation of Hebei Province of China(Grant No.H2019206562);the Key Projects of Hebei Education Department(Grant No.ZD2017244)。
Widely distributed in plants,ent-kaurane diterpenoids could reduce the incidence of inflammatory.The most important active ingredient of Isodon serra(Maxim.)Hara is ent-kaurane diterpenoids,which contribute to the ant...
关键词：Isodon serra(Maxim.)Hara Network pharmacology Active compounds ent-Kaurane diterpenoids Inflammatory targets 
辽宁省兽类新纪录——远东鼩鼱(Sorex isodon Turov,1924)
《四川师范大学学报（自然科学版）》2021年第3期398-401,共4页青娇 蒋海军 王旭明 唐刻意 王琼 刘少英 陈顺德 
国家自然科学基金(32070424和31670388)
2018年10月,于辽宁省新宾县岗山二道阳岔地区采集到15只鼩鼱标本,基于形态和分子鉴定,确认这批标本为远东鼩鼱(Sorex isodon).该物种为辽宁省兽类新纪录,是远东鼩鼱在我国的最南分布.不同地方的远东鼩鼱种群体色变异也被报道.
关键词：远东鼩鼱 新纪录 辽宁省 体色变异 
Molecular and morphological evidence for a new species of Isodon (Lamiaceae) from southern China
《Plant Diversity》2021年第1期54-62,共9页Ya-Ping Chen Cun-Zhong Huang Yue Zhao Chun-Lei Xiang 
supported by the National Natural Science Foundation of China(Grant no.31670197);the CAS“Light of West China”Program,the Special Funds for the Young Scholars of Taxonomy of the Chinese Academy of Sciences(Grant no.ZSBR-006);the“Ten Thousand Talents Program of Yunnan”(YNWR-QNBJ-2018-279);the“Yunnan Fundamental Research Projects”(2019FI009).
Isodon brevipedunculatus,a new species from southern China,is described and illustrated.The phylogenetic position of the new species within the genus was analyzed based on two nuclear ribosomal DNA regions and an ingr...
关键词：Himalaya-Hengduan Mountains region Isodoninae Mericarp Sino-Japanese region 
Arthrinins E-G, Three Botryane Sesquiterpenoids from the Plant Endophytic Fungus Arthrinium sp. HS66
《Natural Products and Bioprospecting》2020年第4期201-207,共7页Xiao-Zheng Su Jian-Wei Tang Kun Hu Xiao-Nian Li Han-Dong Sun Pema-Tenzin Puno 
supported financially by the National Natural Science Foundation of China(No.81874298);the CAS“Light of West China”program(Pema-Tenzin Puno);the Yunnan Science Fund for Distinguished Young Scholars(2019FJ002).
Arthrinins E-G(1-3),three new sesquiterpenoids possessing non-isoprenoid botryane skeleton,were isolated from the fermentation of an endophytic fungus named Arthrinium sp.HS66 which colonized in the stems of Isodon xe...
关键词：Isodon xerophilus Endophytic fungus Arthrinium Botryane sesquiterpenoid Quantum chemical calculation 
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