the National Natural Science Foundation of China(Nos.22171178,21871174 to B.X.);Innovation Program of Shanghai Municipal Education Commission(No.2019-01-07-00-09-E00008 to B.X.)for financial support;The Sailing Program of Science and Technology Commission of Shanghai Municipality(22YF1413200 to M.G.);Young Talents Sailing Project(Shanghai University to M.G.);Shanghai Overseas Leading Talents Project(M.G.)are also appreciated.
An unprecedented copper nitrate-mediated bond cleavage of alkynes was developed for the modular synthesis of isoxazoles,where either C—S bond or C≡C triple bond was cleaved selectively.Substituents attached to the C...
partial financial support from the National Key R&D Program of China(No.2016YFE0132600);Henan Center for Outstanding Overseas Scientists(No.GZS2020001);Key Scientific and Technological Project of Henan Province(No.212102311068)。
A Ru(Ⅲ)-catalyzed annulation reaction of 2-aminoaromatic aldehydes(ketones)and isoxazoles to afford diverse 3-cyanoquinolines has been developed.Notably,isoxazole acted as a cyclization reagent and nontoxic cyano sou...
We thank the National Natural Science Foundation of China(No.21971072);the Ministry of Science and Technology of the People's Republic of China(No.2016YFA0602900);the Guang Guang dong Natural Science Foundation(No.2018B030308007);the Open Fund of Guangdong Provincial Key Laboratory of Luminescence from Molecular Aggregates(No.2019B030301003)for financial support.
A novel and viable palladium-catalyzed sequential cyclization/functionalization of alkynone O-methyloximes with unactivated vinyl ethers under aerobic conditions was described.The structure of the products could be su...
partial financial support from the Ministry of Science and Technology of China(No.2016YFE0132600);Zhengzhou University。
A selective ring-opening [3+2] cyclization reaction of benzo[d]isoxazoles with 2-bromo-propanamides has been developed.The azaoxyallyl cation intermediates are employed as C^O 3-atom synthon to build oxa-heterocycles ...
A novel approach for the synthesis of trisubstituted isoxazoles from nitroenamines and aromatic aldehydes is developed. L-Proline/potassium carbonate system was employed to promote this process. The reaction underwent...
A series of novel imidazo[1,2-b]isoxazoles 3 and their Mannich bases 4–6 were synthesized via convenient reactions. The reaction of 3-aminoisoxazole 1 with substituted phenacyl bromides 2 in dry ethanol afforded the ...
The efficient cycloaddition reactions were carried out to afford the novel 3,5-disubstituted-dihydroisoxazoles from methyl undec-10-enoate and isoxazoles, triazole and tetrazolo-triazole from methyl undec-10-ynoate. T...
Suzuki-Miyaura coupling reaction of N-protected 4-iodopheyl alanine isoxazoles with arylboronic acids,catalyzed by palladium,efficiently produce benzyl-N-(4-bipheyl)-2-(3-methyl-5(E)-2-aryl-1-ethenyl-4-isoxazolyl...
We thank the National Natural Science Foundation of China(No.20562005);NSF of Jiangxi Province for financial support.
A novel facile procedure for traceless solid-phase synthesis of 3-substituted isoxazoles in good yields and with excellent purities using polymer-supported vinyl selenide has been developed.