PROTEOGLYCAN

作品数：44被引量：170H指数：7
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相关领域：医药卫生更多>>
相关作者：李媛崔慧斐李亚妤孟庆华薛冉更多>>
相关机构：山东大学浙江中医药大学首都医科大学附属北京佑安医院河北医科大学更多>>
相关期刊：《Chinese Medical Journal》《食品与药品》《肝脏》《Science Bulletin》更多>>
相关基金：国家自然科学基金浙江省自然科学基金首都卫生发展科研专项更多>>
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A tumor-associated heparan sulfate-related glycosaminoglycan promotes the generation of functional regulatory T cells
《Cellular & Molecular Immunology》2023年第12期1499-1512,共14页Leticia Martín-Cruz Marcos Viñuela Ioanna Kalograiaki Alba Angelina Paola Oquist-Phillips Irene Real-Arévalo Francisco Javier Cañada JoséIgnacio Tudela Luis Moltó Jesús Moreno-Sierra JoséLuis Subiza Oscar Palomares 
upported by grants FEI 16_60 from Art.834154605(138/2012)(24/2013),SAF-2017-84978-R from MINECO(Spain)and PID2020-114396RB-I00 from Ministerio de Ciencia e Innovación(Spain)to OP and PID2021-123781OB-C22 to FJC funded by MCIN/AEI/10.13039/501100011033(Spain)and RTC-2015-3805-1 from MINECO to Inmunotek SL.LM-C and AA were recipients of FPU and UCM predoctoral fellowships,respectively.
Functional Tregs play a key role in tumor development and progression,representing a major barrier to anticancer immunity.The mechanisms by which Tregs are generated in cancer and the influence of the tumor microenvir...
关键词：Tumoral carbohydrate A10 Heparan sulfate-related proteoglycan Cancer immunology Dendritic cell Regulatory T cell 
Decellularized extracellular matrix particle-based biomaterials for cartilage repair applications被引量：2
《Journal of Materials Science & Technology》2023年第29期194-203,共10页Peng Guo Nan Jiang Carina Mini Gregor Miklosic Songsong Zhu Andrea J.Vernengo Matteo D’Este Sibylle Grad Mauro Alini Zhen Li 
AO Foundation and AOSpine Inter-national.Peng Guo and Nan Jiang were funded by Sino Swiss Sci-ence and Technology Cooperation Program(Nos.EG-CN_01-032019 and EG-CN_04-042018);China Scholarship Council.MD and GM gratefully acknowledge funding from the Swiss National Sci-ence Foundation(SNSF,No.310030E_189310).
Cartilage Decellularized ExtraCellular Matrix(dECM)materials have shown promising cartilage regenera-tion capacity due to their chondrogenic bioactivity.However,the limited retention of ECM components and the reduced ...
关键词：Cartilage tissue engineering Decellularized extracellular matrix Proteoglycan integrity Biomimetic hydrogels Biomaterial Bioink 
Pathology-induced NG2 proteoglycan expression in microglia
《Neural Regeneration Research》2023年第4期801-802,共2页Erika Meyer Anja Scheller 
Oligodendrocyte precursor cells(OPCs)and microglia are two very fascinating cell types with a multitude of important but different functions.At a first glance,they appear not to share many cellular properties,nor are ...
关键词：NG2 WOUND FIGURE 
The contribution of proteoglycans to heterogeneity and temozolomide resistance of glioblastoma cells
《Journal of Cancer Metastasis and Treatment》2023年第1期431-444,共14页Sofia A.Nikitina Dmitry K.Sokolov Alexandra Y.Tsidulko Anastasia V.Strokotova Elizaveta Fasler Kan Elvira V.Grigorieva 
This work was supported by the Russian Science Foundation(Grant No.21-15-00285)in part of GR and HS biosynthesis;within the state assignment of Ministry of Science and Higher Education of the Russian Federation(theme No.122032200240-8)in part of GB cells characterization and PGs expression.
Aim:Heterogeneity of glioblastoma(GB)cells significantly contributes to tumor resistance against temozolomide(TMZ)and the development of disease relapse.Multiple molecular mechanisms are involved in this process,yet t...
关键词：Glioblastoma temozolomide resistance extracellular matrix PROTEOGLYCAN GLYCOSAMINOGLYCAN heparan sulfate chondroitin sulfate glucocorticoid receptor 
Breast-conserving surgery and sentinel lymph node biopsy for breast cancer and their correlation with the expression of polyligand proteoglycan-1被引量：1
《World Journal of Clinical Cases》2022年第10期3113-3120,共8页Fu-Ming Li Dan-Ying Xu Qi Xu Yan Yuan 
Supported by Jiaxing Science and Technology Project,No. 2021AD30119
BACKGROUND Breast cancer is a malignant tumor with an unclear etiology and is the most common malignant tumor in women.Surgery is the main clinical treatment for breast cancer.Although traditional total mastectomy com...
关键词：Breast preservation Sentinel lymph node biopsy Breast cancer Clinical effectiveness Polyligand proteoglycan-1 
Bioactive extracellular matrix scaffolds engineered with proangiogenic proteoglycan mimetics and loaded with endothelial progenitor cells promote neovascularization and diabetic wound healing被引量：2
《Bioactive Materials》2022年第4期460-473,共14页Siqi He Tanaya Walimbe Hongyuan Chen Kewa Gao Priyadarsini Kumar Yifan Wei Dake Hao Ruiwu Liu Diana L.Farmer Kit S.Lam Jianda Zhou Alyssa Panitch Aijun Wang 
partially supported by California Institute for Regenerative Medicine[grant number DISC1-10516-0];Shriners Hospitals for Children developmental research award[grant number 87200-NCA-19];supported by NCI P30CA093373 Cancer Center Support Grant.
Diabetic ischemic wound treatment remains a critical clinical challenge.Neovascularization plays a significant role in wound healing during all stages of the tissue repair process.Strategies that enhance angiogenesis ...
关键词：Diabetic ischemic wound ECM scaffold Endothelial progenitor cells NEOVASCULARIZATION Wound healing 
Proteoglycans and their functions in esophageal squamous cell carcinoma被引量：5
《World Journal of Clinical Oncology》2021年第7期507-521,共15页Yun Zhu Annie Lai Man Cheung 
Supported by Research Grants Council of the Hong Kong SAR,China,No.17111016 and No.17100819.
Esophageal squamous cell carcinoma(ESCC)is a highly malignant disease that has a poor prognosis.Its high lethality is mainly due to the lack of symptoms at early stages,which culminates in diagnosis at a late stage wh...
关键词：Esophageal squamous cell carcinoma PROTEOGLYCAN GLYCOSAMINOGLYCAN SERGLYCIN Extracellular matrix Biomarker 
Glycosylation of dentin matrix protein 1 is critical for fracture healing via promoting chondrogenesis被引量：3
《Frontiers of Medicine》2019年第5期575-589,共15页Hui Xue Dike Tao Yuteng Weng Qiqi Fan Shuang Zhou Ruilin Zhang Han Zhang Rui Yue Xiaogang Wang Zuolin Wang Yao Sun 
Key Project of Chinese National Programs for Research and Development (No.2016YFC1102075, Yao Sun);National Natural Science Foundation of China (Nos.81470715, 81771043, 81822012, Yao Sun;81770873, 81722031, Xiaogang Wang;81670962, Zuolin Wang);Shanghai Health System (No.2017BR009 , Yao Sun ), Tongji University (Nos.TJ15042119036 and TJ2000219143, Zuolin Wang);Chinese Universities Scientific Fund (No.kx0200020173386, Rui Yue);We would like to appreciate Dr.Chunlin Qin (College of Dentistry, Texas A&M University) for providing the DMP1-N antibody and assistance.We thank Qigang Wang Group, School of Chemical Science and Engineering, Tongji University for providing biom echanical testing machine.We would also like to thank Xiaojuan Yang, Gongchen Li, and Mengmeng Liu for their help in revising the paper.
Fractures are frequently occurring diseases that endanger human health. Crucial to fracture healing is cartilage formation, which provides a bone-regeneration environment. Cartilage consists of both chondrocytes and e...
关键词：fracture extracellular MATRIX DENTIN MATRIX protein 1 PROTEOGLYCAN CARTILAGE 
Mucin-like glycopolymer gels in electrosensory tissues generate cues which direct electrolocation in amphibians and neuronal activation in mammals被引量：1
《Neural Regeneration Research》2019年第7期1191-1195,共5页James Melrose 
supported by the National Health and Medical Research Council Project,No.1004032
Mucin-like glycoproteins have established roles in epithelial boundary protection and lubricative roles in some tissues.This mini-review illustrates alternative functional roles which rely on keratan sulphate and sial...
关键词：mucin GLYCOPOLYMERS keratan SULFATE ELECTROLOCATION monosulphated keratan SULFATE neuroregulation GLYCOSAMINOGLYCAN neurosensory hair cells neurosensory PROTEOGLYCAN 
The Interaction(s) between Calf-Skin Hyaluronic Acid (Hyaluronan) and Dermal Type I Calf-Skin Collagen under 254 nm UV Radiation: Ability of Hyaluronan to Alter Qualitative and Quantitative Dimerization of Collagen Tyrosine Residues
《Open Journal of Physical Chemistry》2019年第2期51-59,共9页Julian M.Menter La Toya Freeman Ortega Edukye 
The extracellular matrix (ECM) is the non-cellular component present within all tissues and organs, providing not only essential physical scaffolding for the cellular constituents and initiating crucial biochemical an...
关键词：Extracellular Matrix (ECM) PROTEOGLYCAN Type I COLLAGEN Tyrosine DITYROSINE Fluorescence UV Radiation Rate of DITYROSINE Formation PHOTODIMERIZATION 
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