the National Natural Science Foundation of China:Therapy which Invigorating Kidney and Strengthening Bone Regulates the Balance between Osteoblast and Osteoclast in Treating Rheumatoid Arthritis Bone Destruction:a Mechanism Study (No. 82074223);the Therapeutic Method of Tonifying Kidney and Strengthening Bone Regulates the Bone Marrow Mesenchymal Stem Cells’ Differentiation in Treating Rheumatoid Arthritis:a Mechanism Study (No. 82274435);the Fifth Batch of National Training Program for Clinical Excellence in Chinese Medicine (No. 2022178)。
OBJECTIVE: To compare the efficacy and safety of different Traditional Chinese Medicine(TCM)-based kidney-tonifying and bone-strengthening therapies for rheumatoid arthritis(RA). METHODS: The current Bayesian network ...
Background and purpose Tenecteplase(TNK)has demonstrated non-inferiority to alteplase in patients who had an acute ischaemic stroke presenting within 4.5 hours from symptom onset.The trial is aimed to explore the effi...
supported by National Natural Science Foundation of China (NSFC);Youth program (Grant No: 22101173);Fundamental Research Funds for the Central Universities (23X010301599);“Thousand Talents Plan, Youth project”;startup funding from Shanghai Jiao Tong University (SJTU)。
Based on rational design, benzoyl cyanide, a well-known ionic acylating reagent, has been developed as a general radical acylating reagent for benzylic site-selective acylation reactions for the first time. Using visi...
support was from Tianjin University(2024XJD-0062);the National Natural Science Foundation of China(No.22371203).
Traditional reduction coupling reactions of two bromides typically rely on transition metal catalysis.Here,we introduce the development of a visible-light catalytic direct reduction coupling reaction between α-CF_(3)...
Background and Objectives: The indication for treatment in HBsAg-positive patients with low viral load and normal transaminases requires an assessment of fibrosis. In resource-limited settings, free hepatic fibrosis e...
Spontaneous Tumor Lysis Syndrome (STLS) is a rare oncologic condition caused by the breakdown of neoplastic tissue in the absence of traditional anti-tumor therapy. It is postulated that cancers with rapidly dividing ...
supported by the China National Funds for Distinguished Young Scientists (51925104);the National Natural Science Foundation of China (NSFC) (51871162 and 52173251);NSFC-Guangdong Province Joint Program (U21A2084);the Central Guidance on Local Science and Technology Development Fund of Hebei Province (226Z1303G).
Infections with multidrug-resistant(MDR)Gram-negative bacteria,such as MDR Escherichia coli(E.coli),remain a challenge due to the lack of safe antibiotics and high fatality rates under anti-infection therapies.This wo...
supported by the National Key R&D Program of China (2021YFA1500200);National Natural Science Foundation of China (22001129, 92256301, 92156006, 21971119 and 22221002);Program of Introducing Talents of Discipline to Universities (‘111’ project, B06005) of the Ministry of Education of China;Haihe Laboratory of Sustainable Chemical Transformations;Fundamental Research Funds for the Central Universities;New Cornerstone Science Foundation through XPLORER PRIZE
Iron catalysts are ideal transition metal catalysts because of the Earths abundant,cheap,biocompatible features of iron salts.Iron catalysts often have unique open-shell structures that easily undergo spin crossover i...
P-Coumaric acid was previously reported to contain antioxidant,antidiabetic,anti-inflammatory,antiplatelet,antiulcer and anticancer activities.Along with these,the present work has been conducted to study the antibact...
Environmental pollution is a major challenge faced by human beings, and is becoming more serious due to increasing urbanization and industrialization. Catalysis is the key technology for environmental remediation. As...