CORONAVIRUSES

作品数:52被引量:111H指数:6
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Individual virome analysis reveals the general co-infection of mammal-associated viruses with SARS-related coronaviruses in bats
《Virologica Sinica》2024年第4期565-573,共9页Hao-Rui Si Ke Wu Jia Su Tian-Yi Dong Yan Zhu Bei Li Ying Chen Yang Li Zheng-Li Shi Peng Zhou 
supported by the National Key R&D Program of China(2021YFC2300901 to P.Z.);China Natural Science Foundation for outstanding scholars(82325032 to P.Z.);the Self-Supporting Program of Guangzhou Laboratory(SRPG22-001 to P.Z.;GZNL2023A01001 to ZLS).
Bats are the natural reservoir hosts for SARS-related coronavirus(SARSr-CoV)and other highly pathogenic microorganisms.Therefore,it is conceivable that an individual bat may harbor multiple microbes.However,there is l...
关键词:Bat Microbiome SARS-related coronavirus CO-INFECTION Alphacoronavirus 
Antigen epitopes of animal coronaviruses:a mini-review
《Animal Diseases》2024年第1期19-26,共8页Mingjun Su Guanghui Zheng Xiangwen Xu Houhui Song 
supported by the Natural Science Foundation of Zhejiang Province(Q23C180006);the Zhejiang A&F University Talent Initiative Project(118-203402005901).
Coronaviruses are widespread in nature and can infect mammals and poultry,making them a public health concern.Globally,prevention and control of emerging and re-emerging animal coronaviruses is a great challenge.The m...
关键词:Animal coronavirus Antigen epitope B-cell epitope T-cell epitope Immune responses Vaccines 
Pangolin HKU4-related coronaviruses found in greater bamboo bats from southern China
《Virologica Sinica》2023年第6期868-876,共9页Min Guo Kai Zhao Xingwen Peng Xiangyang He Jin Deng Bo Wang Xinglou Yang Libiao Zhang 
the Special Foundation for the National Science and Technology Basic Research Program of China(2021FY100303);the Guangdong Provincial Science and Technology Program(2021B1212050021,2021B1212110003);the GDAS Special Project of Science and Technology Development(2021GDASYL-20210103052);the Young Top-notch Talent Cultivation Program of Hubei Province and the Youth Innovation Promotion Association of the Chinese Academy of Sciences(CAS)(2019328).
Coronavirus(CoV)spillover originating from game animals,particularly pangolins,is currently a significant concern.Meanwhile,vigilance is urgently needed for coronaviruses carried by bats,which are known as natural res...
关键词:CORONAVIRUS Pangolin HKU4r-CoV Bat HKU4r-CoV Tylonycteris robustula Spillover risk 
Identification of a receptor tyrosine kinase inhibitor CP-724714 inhibits SADS-CoV related swine diarrhea coronaviruses infection in vitro
《Virologica Sinica》2023年第5期778-786,共9页Ling Zhou Cheng Li Ruiyu Zhang Qianniu Li Yuan Sun Yaoyu Feng Tian Lan Jingyun Ma 
This work was funded by the Guangdong Major Project of Basic and Applied Basic Research(No.2020B0301030007);the Natural Science Foundation of Guangdong Province(2022A1515012473,2020A1515010220);the Science and Technology Program of Guangzhou City of China(2023B03J1310.)。
The outbreak of the COVID-19 epidemic in 2020 has caused unprecedented panic among all mankind,pointing the major importance of effective treatment.Since the emergence of the swine acute diarrhea syndrome coronavirus(...
关键词:SADS-CoV CORONAVIRUS Antiviral agents HER2 CP-724714 
Diversity of coronaviruses in wild and domestic birds in Vietnam
《Asian Pacific Journal of Tropical Medicine》2022年第10期442-450,共9页Vasily Y.Marchenko Natalia P.Kolosova Alexey V.Danilenko Maria K.Bragina Tran Thi Nhai Alexander B.Ryzhikov 
The reported study was funded by RFBR,project number 20-04-60051.
Objective:To investigate the genetic diversity of coronaviruses in wild and domestic birds in the bird park and live poultry markets of Ca Mau province in Vietnam in 2020.Methods:A total of 228 samples(121 from wild b...
关键词:Avian coronavirus Gammacoronavirus Deltacoronavirus Surveillance Wild birds POULTRY VIETNAM 
The high diversity of SARS-CoV-2-related coronaviruses in pangolins alerts potential ecological risks被引量:3
《Zoological Research》2021年第6期834-844,共11页Min-Sheng Peng Jian-Bo Li Zheng-Fei Cai Hang Liu Xiaolu Tang Ruochen Ying Jia-Nan Zhang Jia-Jun Tao Ting-Ting Yin Tao Zhang Jing-Yang Hu Ru-Nian Wu Zhong-Yin Zhou Zhi-Gang Zhang Li Yu Yong-Gang Yao Zheng-Li Shi Xue-Mei Lu Jian Lu Ya-Ping Zhang 
This work was supported by the National Key Research and Development Projects of the Ministry of Science and Technology of China,National Key Research and Development Program of China(2021YFC0863300);Ministry of Agriculture of China(2016ZX08009003-006);Key Program of Chinese Academy of Sciences(KJZD-SW-L11);Animal Branch of the Germplasm Bank of Wild Species,Chinese Academy of Sciences(the Large Research Infrastructure Funding)。
Understanding the zoonotic origin and evolution history of SARS-CoV-2 will provide critical insights for alerting and preventing future outbreaks.A significant gap remains for the possible role of pangolins as a reser...
关键词:SARS-CoV-2 PANGOLIN Recombination DIVERSITY SEQUENCING MTDNA 
Porcine Coronaviruses: Overview of the State of the Art被引量:23
《Virologica Sinica》2021年第5期833-851,共19页Hanna Turlewicz-Podbielska Małgorzata Pomorska-Mo´l 
supported by the National Science Centre,Poland,under research project(DEC-2014/13/B/NZ6/02566);statutory funding 506.514.05.00 of the Department of Preclinical Sciences and Infectious Diseases,Faculty of Veterinary Medicine and Animal Science,Poznan University of Life Sciences,Poznan,Poland。
Like RNA viruses in general,coronaviruses(CoV)exhibit high mutation rates which,in combination with their strong tendency to recombine,enable them to overcome the host species barrier and adapt to new hosts.It is curr...
关键词:CORONAVIRUS PIG EMERGING Re-emerging 
Interspecies transmission and evolution of the emerging coronaviruses: perspectives from bat physiology and protein spatial structure
《Frontiers of Agricultural Science and Engineering》2020年第2期218-226,共9页Baicheng HUANG Kegong TIAN 
funded by Luoyang Heluo Talent Plan。
Emergent coronaviruses(CoVs)such as SARS-CoV and MERS-CoV have posed great threats to public health worldwide over the past two decades.Currently,the emergence of SARS-CoV-2 as a pandemic causes greater public health ...
关键词:BAT CORONAVIRUS EVOLUTION host receptor spike protein transmission 
Comparison of lentiviruses pseudotyped with S proteins from coronaviruses and cell tropisms of porcine coronaviruses被引量:2
《Virologica Sinica》2016年第1期49-56,共8页Jingjing Wang Feng Deng Gang Ye Wanyu Dong Anjun Zheng Qigai He Guiqing Peng 
supported by the National Natural Science Foundation of China (Grant No.31372440)
The surface glycoproteins of coronaviruses play an important role in receptor binding and cell entry. Different coronaviruses interact with their specific receptors to enter host cells. Lentiviruses pseudotyped with t...
关键词:Coronavirus spike proteins receptor binding cell entry pseudotyped virus 
Indirect Enzyme-Linked Immunosorbent Assay Based on the Nucleocapsid Protein of SARS-like Coronaviruses被引量:1
《Virologica Sinica》2009年第2期146-151,共6页Jun-fa YUAN Yan LI Hua-jun ZHANG Peng ZHOU Zhen-hua KE Yun-zhi ZHANG Zheng-li SHI 
The State Key Program for Basic Research Grant (2005CB523004) ;The Knowledge InnovationProgram Key Project (KSCX1-YW-R-07).
The nucleocapsid protein(N) is a major structural protein of coronaviruses. The N protein of bat SARS-like coronavirus(SL-CoV) has a high similarity with that of SARS-CoV. In this study,the SL-CoV N protein was expres...
关键词:SARS-like CoV Nucleocapsid protein Indirect ELISA 
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