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作品数:377被引量:877H指数:13
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Celiac disease:From genetics to epigenetics
《World Journal of Gastroenterology》2022年第4期449-463,共15页Elisa Gnodi Raffaella Meneveri Donatella Barisani 
Celiac disease(CeD)is a multifactorial autoimmune disorder spread worldwide.The exposure to gluten,a protein found in cereals like wheat,barley and rye,is the main environmental factor involved in its pathogenesis.Eve...
关键词:Celiac disease EPIGENETICS DNA methylation Histone modifications Long non-coding RNAs MICRORNAS 
Hepatitis C virus-related mixed cryoglobulinemia: Is genetics to blame?被引量:1
《World Journal of Gastroenterology》2013年第47期8910-8915,共6页Laura Gragnani Elisa Fognani Alessia Piluso Anna Linda Zignego 
Supported by Grants from the"Associazione Italiana per la Ricerca sul Cancro"Investigator Grant,No.1461;‘‘Istituto Toscano Tumori’’;"Fondazione Istituto di Ricerche Virologiche Oretta Bartolomei Corsi";"Ente Cassa di Risparmio di Firenze"
Mixed cryoglobulinemia(MC)is the extrahepatic manifestation most strictly correlated with hepatitis C virus(HCV)infection;it is a benign autoimmune and lymphoproliferative disorder that evolves to lymphoma in5%-10%of ...
关键词:Hepatitis C virus Mixed CRYOGLOBULINEMIA Genetics VIRAL pathogenetic FACTORS Host pathogenetic FACTORS 
MicroRNAs in inflammatory bowel disease-pathogenesis,diagnostics and therapeutics被引量:19
《World Journal of Gastroenterology》2012年第34期4629-4634,共6页Mehmet Coskun Jacob Tveiten Bjerrum Jakob Benedict Seidelin Ole Haagen Nielsen 
Supported by Grants from Fonden til Lgevidenskabens Fremme(the AP Mller Foundation);the Family Erichsen Memorial Foundation;the Lundbeck Foundation;the Axel Muusfeldts Foundation;the Foundation of Aase and Ejnar Danielsen
The pathogenesis of inflammatory bowel disease (IBD) is complex and largely unknown. Until recently, research has focused on the study of protein regulators in inflammation to reveal the cellular and molecular network...
关键词:Biomarker Crohn's disease DIAGNOSTICS In-flammatory bowel disease MicroRNA THERAPEUTICS Ulcer-ative colitis 
Role of genetics in the diagnosis and prognosis of Crohn's disease被引量:4
《World Journal of Gastroenterology》2012年第2期105-118,共14页Epameinondas V Tsianos Konstantinos H Katsanos Vasileios E Tsianos 
Considering epidemiological,genetic and immunological data,we can conclude that the inflammatory bowel diseases are heterogeneous disorders of multifactorial etiology in which hereditability and environment interact t...
关键词:Crohn's GENETICS POLYMORPHISM Diagnosis Prognosis Genome wide scan Genetic consortium 
Role of genetics in the diagnosis and prognosis of Crohn's disease被引量:8
《World Journal of Gastroenterology》2011年第48期5246-5259,共14页Epameinondas V Tsianos Konstantinos H Katantions Vasileios E Tsianos 
Considering the epidemiological, genetic and immunological data, we can conclude that the inflammatory bowel diseases are heterogeneous disorders of multifactorial etiology in which hereditability and environment inte...
关键词:Crohn's disease GENETICS POLYMORPHISM Diagnosis PROGNOSIS Genome-wide scan Genetic consortium 
Role of genetics in prediction of disease course and response to therapy被引量:3
《World Journal of Gastroenterology》2010年第21期2609-2615,共7页Severine Vermeire Gert Van Assche Paul Rutgeerts 
The clinical course of Crohn's disease and ulcerative colitis is highly variable between patients,and this has therapeutic implications.A number of clinical features have been identified,which predict a mild or more s...
关键词:GENETICS Inflammatory bowel diseases PHARMACOGENETICS 
Effect of omeprazole and domperidone on adult asthmatics with gastroesophageal reflux被引量:5
《World Journal of Gastroenterology》2007年第11期1706-1710,共5页Bhavneesh Sharma Manisha Sharma Mradul Kumar Daga Gopal Krishan Sachdev Elliott Bondi 
a research grant from the University of Delhi, No. 52301/01;Glaxo Smithkline Pharmaceuticals Limited and Dr. Reddy's Laboratories Ltd, No. 9834512
AIM: To study the effect of combined omeprazole(Ome) and domperidone(Dom) therapy on asthma symptoms and pulmonary function in asthmatics with gastroesoph- ageal reflux. METHODS: We selected 198 asthmatics with ...
关键词:Asthma REFLUX Gastroesophageal reflux disease Antireflux therapy PROKINETIC OMEPRAZOLE 
Differences in characteristics of patients with and without known risk factors for hepatocellular carcinoma in the United States被引量:1
《World Journal of Gastroenterology》2007年第5期781-784,共4页Jon D Dorfman Richard Schulick Michael A Choti Jean-Francois H Geschwind Ihab Kamel Michael Torbenson Paul J Thuluvath 
AIM: To examine the clinical characteristics of a subgroup of patients with hepatocellular carcinoma (HCC) and compare them to those with known risk factors. METHODS: We used the HCC database of 306 patients seen ...
关键词:Hepatocellular carcinoma Patient charaocteristics Risk factors 
The genetics of nicotine dependence:Relationship to Pancreatic cancer被引量:5
《World Journal of Gastroenterology》2006年第46期7433-7439,共7页Stewart L MacLeod Parimal Chowdhury 
Smoking of tobacco products continues to be a major cause of worldwide health problems. Epidemiological studies have shown that tobacco smoking is the greatest risk factor for the development of pancreatic cancer. Smo...
关键词:SMOKING Pancreatic cancer Nicotine dependence GENETICS POLYMORPHISM Nicotine metabolism 
Contribution of genetics to a new vision in the understanding of inflammatory bowel disease被引量:1
《World Journal of Gastroenterology》2006年第30期4784-4787,共4页AS Pe■a 
Inflammatory bowel diseases (IBD), such as Crohn's disease (CD) and ulcerative colitis (UC), are chronic inflammatory autoimmune conditions of the gastrointestinal tract. Other organs, such as the eyes, skin an...
关键词:Inflammatory bowel disease Crohn's disease Ulcerative colitis GENETICS AUTOIMMUNITY Major histocompatibility complex 
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