PICORNAVIRUS

作品数：8被引量：15H指数：2
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相关领域：医药卫生农业科学更多>>
相关作者：任龙焦宁更多>>
相关机构：北京大学中国科学院更多>>
相关期刊：《Virologica Sinica》《World Journal of Gastroenterology》《Biosafety and Health》《Acta Epileptologica》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
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Enterovirus A71 antivirals:Past,present,and future被引量：2
《Acta Pharmaceutica Sinica B》2022年第4期1542-1566,共25页Jun Wang Yanmei Hu Madeleine Zheng 
This research was supported by the National Institute of Allergy and Infectious Diseasess of Health(NIH,USA,grants AI147325 and AI157046);the Arizona Biomedical Research Commission Centre Young Investigator grant(ADHS18-198859,USA)to Jun Wang;Yanmei Hu was supported by the NIH training grant T32 GM008804(USA).
Enterovirus A71(EV-A71)is a significant human pathogen,especially in children.EV-A71 infection is one of the leading causes of hand,foot,and mouth diseases(HFMD),and can lead to neurological complications such as acut...
关键词：Enterovirus A71 EV-A71 AntiviralsAcute flaccid myelitis Hand Foot and mouth disease(HFMD) PICORNAVIRUS 2C protein 
Correction to: Porcine Picornavirus 3C Protease Degrades PRDX6 to Impair PRDX6-mediated Antiviral Function
《Virologica Sinica》2021年第6期1688-1689,共2页Congcong Wang Huanhuan Feng Xiangle Zhang Kangli Li Fan Yang Weijun Cao Huisheng Liu Lili Gao Zhaoning Xue Xiangtao Liu Zixiang Zhu Haixue Zheng 
Correction to:Virologica Sinica(2021)36:948-957 https://doi.org/10.1007/s12250-021-00352-4 Due to our negligence,the original version of this article,published online on March 15,2021,contained a mistake in Figure 2E(...
关键词：PRDX6 MISTAKE CORRECTION 
Porcine Picornavirus 3C Protease Degrades PRDX6 to Impair PRDX6-mediated Antiviral Function被引量：1
《Virologica Sinica》2021年第5期948-957,共10页Congcong Wang Huanhuan Feng Xiangle Zhang Kangli Li Fan Yang Weijun Cao Huisheng Liu Lili Gao Zhaoning Xue Xiangtao Liu Zixiang Zhu Haixue Zheng 
supported by grants from the National Key R&D Program of China(2017YFD0501103);the Key Development and Research Foundation of Yunnan(2018BB004);the Chinese Academy of Agricultural Science and Technology Innovation Project(Y2017JC55);Central Public-interest Scientific Institution Basal Research Fund(1610312016013 and 1610312017003)。
Peroxiredoxin-6(PRDX6)is an antioxidant enzyme with both the activities of peroxidase and phospholipase A2(PLA2),which is involved in regulation of many cellular reactions.However,the function of PRDX6 during virus in...
关键词：Porcine picornavirus Peroxiredoxin-6(PRDX6) 3Cpro Phospholipase A2(PLA2) ANTAGONISM 
Heat inactivation of foot-and-mouth disease virus,swine vesicular disease virus and classical swine fever virus when air-dried on plastic and glass surfaces被引量：1
《Biosafety and Health》2021年第4期217-223,共7页Thea Kristensen Graham J.Belsham Kirsten Tjørnehøj 
Foot-and-mouth disease virus(FMDV),swine vesicular disease virus(SVDV)and classical swine fever virus(CSFV)all cause important animal diseases.FMDV affects many different cloven-hoofed animals,whereas SVDV and CSFV ar...
关键词：Virus survival PICORNAVIRUS PESTIVIRUS DECONTAMINATION RISK-ASSESSMENT 
EGCG-S Impacts Oxidative Stress and Infection of Enterovirus 69 in Lung Cells
《Advances in Bioscience and Biotechnology》2021年第5期109-124,共16页Hager Mohamed Lee H. Lee Sandra D. Adams 
Enteroviruses are responsible for emerging diseases which cause diverse symptoms and may result in neurological complications. An antiviral with mul...
关键词：ROS Enterovirus 69 PICORNAVIRUS Green Tea Flavanol ANTIOXIDANT Antivi-ral MRC-5 Cells A549 Cells 
The role of picornavirus infection in epileptogenesis
《Acta Epileptologica》2021年第1期37-43,共7页Runxuan Zhang Jie Mu Jing Chi Weijia Jiang Xiaosa Chi 
supported by the National Natural Science Foundation of Shandong,China(ZR2019PH040);the National Natural Science Foundation of China(81901321).
Picornaviridae are a family of small positive-strand RNA viruses,and transmitted via the respiratory or fecal-oral route.The neurotropic picornaviruses can induce acute or late recurrent seizures following central ner...
关键词：Picornaviridae infection Theiler’s murine encephalomyelitis virus SEIZURE Immune response 
A perspective on picornavirus inhibitors and concrete evolution of WIN compounds
《Journal of Chinese Pharmaceutical Sciences》2012年第6期509-525,共17页任龙 焦宁 
National Basic Research Program of China (973Program,Grant No. 2009CB825300);National Science Foundation ofChina (Grant No. 21172006)
The family Picornaviridae is one of the largest families of human viral pathogens,causing an extensive range of clinical manifestations from mild fever,common cold to serious paralytic poliomyelitis,COPD,etc.,some of ...
关键词：PICORNAVIRUS Antiviral agent Capsid binding inhibitor WIN compound Pleconaril 
Rupintrivir is a promising candidate for treating severe cases of Enterovirus-71 infection被引量：11
《World Journal of Gastroenterology》2010年第2期201-209,共9页Zhang, Xiao-Nan Song, Zhi-Gang Jiang, Ting Shi, Bi-Sheng Hu, Yun-Wen Yuan, Zheng-Hong 
Supported by Start-up Fund(No.KSF0062)of the Shanghai Public Health Clinical Center
AIM:To evaluate the suitability of rupintrivir against Enterovirus 71(EV71)induced severe clinical symptoms using computational methods. METHODS:The structure of EV71 3C protease was predicted by homology modeling.The...
关键词：Rupintrivir Hand foot and mouth disease Molecular mechanics Poisson-Boltzmann/surface area Molecular mechanics Generalized-Born/surface area Homology modeling PICORNAVIRUS 
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