SCRAMBLE

作品数:28被引量:35H指数:4
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相关领域:医药卫生更多>>
相关作者:李炳志元英进贾斌贾斌戴俊彪更多>>
相关机构:天津大学教育部清华大学北京化工大学更多>>
相关期刊:《世界建筑导报》《US-China Foreign Language》《Wuhan University Journal of Natural Sciences》《Science China(Life Sciences)》更多>>
相关基金:国家自然科学基金天津市科技计划国家高技术研究发展计划国家科技支撑计划更多>>
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Inter-chromosomal insertions into wild-type chromosomes induced by SCRaMbLE
《Frontiers of Chemical Science and Engineering》2024年第9期125-135,共11页Sijie Zhou Junyanrui Li Xichen Cui Ying Wang Ying-Jin Yuan 
supported by the National Key Research and Development Program of China(Grant No.2021YFC2100800);the National Natural Science Foundation of China(Grant No.22208241);China Postdoctoral Science Foundation(Grant No.2023M732591);the Key R&D Program of Shandong Province,China(Grant No.2022SFGC0102).
Genomic rearrangements play a crucial role in shaping biological phenotypic diversity and driving species evolution.Synthetic chromosome rearrangement and modification by LoxP-mediated evolution(SCRaMbLE)has been appl...
关键词:genomic rearrangements synthetic yeast genome SCRAMBLE inter-chromosomal insertions synthetic biology 
The Great Holiday Scramble
《China Weekly》2024年第6期62-62,共1页Sam Duckett 
In the lead-up to the May Day holiday,my wife and I brainstormed the best way to spend our upcoming five-day break.After a calm and quiet week at home during the Qingming,or Tomb Sweeping Festival,we wanted to shake t...
关键词:DAUGHTER VENTURE SPEND 
涩谷SCRAMBLE SQUARE(东座) 日本东京都涩谷区
《世界建筑导报》2023年第S02期16-19,共4页金行美佳  
充分发挥涩谷活力的站城一体化再开发站城一体化开发涩谷站拥有多个铁路设施和东京都最大的巴士总站,日均客流量达330万人次,是世界上屈指可数的超大型交通枢纽。然而,自大正时代(1912-1926年)以来,由于多次的扩建改建,不仅换乘系统变...
关键词:无障碍设计 站城一体化 东京都 铁路设施 客流量 交通动线 换乘系统 大型交通枢纽 
The construction and optimization of engineered yeast chassis for efficient biosynthesis of 8-hydroxygeraniol
《mLife》2023年第4期438-449,共12页Yu Zhang Mengdi Yuan Xinxin Wu Qiuhui Zhang Yuzhu Wang Liming Zheng Tsan-Yu Chiu Huiming Zhang Lei Lan Feng Wang Ying Liao Xuemei Gong Shirui Yan Yun Wang Yue Shen Xian Fu 
supported by grants from the National Key Research and Development Program of China (No.2021YFC2100800 to Y.Z.);the Science,Technology and Innovation Commission of Shenzhen Municipality under grant (No.JCYJ20180507183534578);the Tip-top Scientific and Technical Innovative Youth Talents of Guangdong Special Support Program (2019TQ05Y876 to Y.S.)。
Microbial production of monoterpenoid indole alkaloids(MIAs)provides a sustainable and eco-friendly means to obtain compounds with high pharmaceutical values.However,efficient biosynthesis of MIAs in heterologous micr...
关键词:8-hydroxygeraniol biosynthesis G8H SCRAMBLE synthetic yeast 
Dynamics of synthetic yeast chromosome evolution shaped by hierarchical chromatin organization被引量:4
《National Science Review》2023年第5期234-244,共11页Sijie Zhou Yi Wu Yu Zhao Zhen Zhang Limin Jiang Lin Liu Yan Zhang Jijun Tang Ying-Jin Yuan 
supported by the National Key Research and Development Program of China(2021YFC2100800);the National Natural Science Foundation of China(21621004,31861143017 and 31971351);is part of the Synthetic Yeast Genome Project(http://syntheticyeast.org/sc2-0/)。
Synthetic genome evolution provides a dynamic approach for systematically and straightforwardly exploring evolutionary processes.Synthetic Chromosome Rearrangement and Modification by LoxP-mediated Evolution(SCRaMbLE)...
关键词:synthetic biology genome rearrangement hierarchical chromatin organization synthetic yeast genome SCRAMBLE Saccharomyces cerevisiae 
Enhancement and mapping of tolerance to salt stress and 5-fluorocytosine in synthetic yeast strains via SCRaMbLE被引量:2
《Synthetic and Systems Biotechnology》2022年第3期869-877,共9页Jianping Kang Jieyi Li Zhou Guo Sijie Zhou Shuxin Su Wenhai Xiao Yi Wu Yingjin Yuan 
supported by the National Key R&D Program of China(2021YFC2102500);National Natural Science Foundation of China(31971351).
Varied environmental stress can affect cell growth and activity of the cellular catalyst.Traditional path of adaptive evolution generally takes a long time to achieve a tolerance phenotype,meanwhile,it is a challenge ...
关键词:SCRAMBLE Saccharomyces cerevisiae Structural variation GCN20 TOLERANCE 
Directed yeast genome evolution by controlled introduction of trans-chromosomic structural variations被引量:2
《Science China(Life Sciences)》2022年第9期1703-1717,共15页Bin Jia Jin Jin Mingzhe Han Bingzhi Li Yingjin Yuan 
This work was supported by the Ministry of Science and Technology,the National Key Research and Development Program of China(2021YFC2100800);the National Natural Science Foundation of China(31800719,31861143017,21621004).
Naturally occurring structural variations(SVs)are a considerable source of genomic variation that can reshape the 3D architecture of chromosomes.Controllable methods aimed at introducing the complex SVs and their rela...
关键词:directed genome evolution structural variations SCRAMBLE synthetic genome synthetic biology 
基因组设计与合成:从复写到理性设计被引量:2
《合成生物学》2021年第2期247-255,共9页汪君仪 武晓乐 曹月阳 李炳志 
真核微生物基因组的人工设计与合成(2018YFA0900100)。
基因组合成相关技术的进步推动人工基因组合成能力不断取得突破,合成基因组学成为了近年来的研究热点,逐步完成了病毒、原核生物基因组的全合成,真核生物基因组设计合成也取得了阶段性突破。在基因组合成的研究过程中,基因组设计的原则...
关键词:合成基因组学 基因组设计 密码子删除 合成型标签 SCRAMBLE 基因组简化 
Low-Temperature Growing Anatase TiO2/SnO2 Multi-dimensional Heterojunctions at MXene Conductive Network for High-Efficient Perovskite Solar Cells被引量:7
《Nano-Micro Letters》2020年第3期199-217,共19页Linsheng Huang Xiaowen Zhou Rui Xue Pengfei Xu Siliang Wang Chao Xu Wei Zeng Yi Xiong Hongqian Sang Dong Liang 
supported by the Science & Technology Project of Anhui Province (16030701091);the Natural Science Research Project of Anhui Provincial Education Department (KJ2019A0030);the Support Project of Outstanding Young Talents in Anhui Provincial Universities (gxyqZD2018006);the National Natural Science Foundation of China(11704002, 31701323);the Anhui Provincial Natural Science Foundation (1908085QF251,1808085MF185)
A multi-dimensional conductive heterojunction structure,composited by TiO2,SnO2,and Ti3C2TX MXene,is facilely designed and applied as electron transport layer in efficient and stable planar perovskite solar cells.Base...
关键词:In situ fabrication Multi-dimensional heterojunction Oxygen vacancy scramble effect Electron transport layer Perovskite solar cells 
A Reversible Data Hiding with Quality Controllable Scheme for Encrypted-Compressed Image
《Wuhan University Journal of Natural Sciences》2019年第5期383-390,共8页LI Xinyan MOU Huajian YAN Bing GAO Li 
Supported by the Chongqing Research Program of Basic Research and Frontier Technology(cstc2017jcyjBX0008);the Graduate Student Research and Innovation Foundation of Chongqing(CYB17026);the Basic Applied Research Program of Qinghai Province(2019-ZJ-7099)
In order to achieve image encryption and data embedding simultaneously, a reversible data hiding(RDH) algorithm for encrypted-compressed image in wavelet domain is proposed. This scheme employs the quality controllabl...
关键词:REVERSIBLE data hiding in encrypted image cross CHAOTIC map DIFFUSE and SCRAMBLE encryption-compression 
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