Cytoskeletal network dysregulation is a pivotal determinant in various immunodeficiencies and autoinflammatory conditions. This report reviews the significance of actin remodeling in disease pathogenesis, focusing on ...
In this paper we present a five-generation kindred with familial eosinophilia, associated with valvular heart disease in one of seven members of the second generation, four of sixteen members of the third generation, ...
Zhejiang Research Center of Stroke Diagnosis and Treatment Technology,No.JBZX-202002;Zhejiang Province Medical Science and Technology Project,No.2020RC061 and No.2018KY872.
BACKGROUND Hypereosinophilia(HE)is defined as a peripheral blood eosinophil count of>1.5×109/L and may be associated with tissue damage.The clinical presentations of HE vary;however,myocardial fibrosis and thrombosis...
BACKGROUND Hypereosinophilia(HE)is a heterogeneous disease of unknown etiology in which tissue and organ injury is inflicted by excess numbers of circulating or infiltrating eosinophils.Herein,we describe a patient wi...
Objective To investigate the Churg-Strauss syndrome (CSS) associated lung involvement, concentrating on clinical characteristics, pathological findings of tung involvements, response to treatment, and prognosis. Me...
Hypereosinophilic syndrome (HES) is a rare disorder that can be seen in various organ systems, but its major tissue target is the heart.' The most characteristic cardiovascular abnormality in HES is endomyocardial ...