UP-REGULATION

作品数：166被引量：662H指数：12
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相关机构：中国科学院华中科技大学海南医学院附属医院第三军医大学大坪医院更多>>
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Demethylation and Up-Regulation of an Oncogene after Hypomethylating Therapy被引量：1
《四川生理科学杂志》2022年第5期897-897,共1页Yao-Chung Liu 
Background:Although hypomethylating agents are currently used to treat patients with cancer,whether they can also reactivate and up-regulate oncogenes is not well elucidated.Methods:We examined the effect of hypomethy...
关键词：SALL4 expression. patients 
Clinical significance and role of up-regulation of SERPINA3 expression in endometrial cancer被引量：2
《World Journal of Clinical Cases》2019年第15期1996-2002,共7页Mian-Li Zhou Fang-Shan Chen Hui Mao 
BACKGROUND Serpin peptidase inhibitor,clade A member 3(SERPINA3)belongs to the serpin family with an inhibitory activity against proteases.Its aberrant expression has been observed in a wide range of tumor cells.Howev...
关键词：SERPIN PEPTIDASE inhibitor clade A member 3 ENDOMETRIAL cancer Quantitative polymerase chain reaction EXPRESSION 
Mechanisms of Up-regulation of 17β-Estrodiol on β-Defensin-2 ( SBD-2) Expression in Epithelial Cells of Ovine Oviduct
《Animal Husbandry and Feed Science》2015年第2期106-110,共5页Bao Tuya Cao Guifang Tu Yong Du Chenguang 
Supported by the National Natural Science Foundation of China(31060328);the Natural Science Foundation of Inner Mongolia(No.2014BS0801);the Doctor's Start-up Fund in Inner Mongolia Medical University(NY2011BQ003);the Youth Entrepreneurship Foundation of Inner Mongolia Medical University(NY2010QN003)
[ Objective] To investigate the mechanisms involved in the Up-regulatory effects of 17β-estrodiol on β-defensin-2 （SBD-2） in epithelial cells of ovine oviduct. [ Methods] Epithelial cells of ovine oviduct were iso...
关键词：17β-estrodiol Oviduct epithelial cells SBD-2 Signaling pathways 
Hyperoxia accelerates progression of hepatic fibrosis by up-regulation of transforming growth factor-β expression被引量：6
《World Journal of Gastroenterology》2014年第11期3011-3017,共7页Sang Hwa Lee Sung-Im Do Hyun-Soo Kim 
Supported by Aerospace Medicine Research Project funded by the Medical Division,Headquarter,Republic of Korea Air Force(2012)
AIM: To investigate the effect of hypoxia or hyperoxia on the progression of hepatic fibrosis and to examine the role of transforming growth factor-β (TGF-β) in the livers of rats exposed to hypoxic or...
关键词：Hepatic fibrosis  Cirrhosis  Hypoxia  Hyperoxia  Transforming growth factor-β 
Up-regulation of VLDL Receptor Expression and Its Signaling Pathway Induced by VLDL and β-VLDL
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2009年第1期1-7,共7页刘志国 李和 李映红 王燕 宗义强 冯友梅 冯宗忱 邓耀祖 屈伸 
supported by grant from National Natural Sciences Foundation of China (No. 39970307);Hubei Provincial Natural Sciences Foundation of China (No. 2005ABA092).
Very low density lipoprotein receptor （VLDLR） is thought to participate in the pathogenesis of atherosclerosis induced by VLDL and β-VLDL. The present study was undertaken to elucidate the effects of VLDL and β-VL...
关键词：VLDLR signal transduction transcriptional regulation 
SPECIFIC UP-REGULATION OF DNA POLYMERASE BY HUMAN PAPILLOMAVIRUS 16
《Chinese Medical Sciences Journal》2008年第2期108-112,共5页Song-nian Liu Wu-yun Bai Russell M Frye Ⅱ Lin Hou Bo Zhang 
Obje, etive To analyze how the infection of human papillomavirus 16 （ HPV16 ） affects expression of DNA poly- merase β（DNA polB） with the aim of probing the mechanism of over-expression of DNA polB in human cance...
关键词：DNA polymerase β human papillomavirus EXPRESSION 
Association between Up-regulation of Fas Ligand Expression and Apoptosis of Tumor-infiltrating Lymphocytes in Human Breast Cancer被引量：2
《Journal of Huazhong University of Science and Technology(Medical Sciences)》2006年第5期573-575,共3页程波 
In order to study the significance of FasL expression in immune escape of breast cancer, FasL protein expression and the number of tumor-infiltrating lymphocytes （TILs） in 40 specimens of breast cancer were detected...
关键词：breast cancer Fas ligand APOPTOSIS tumor-infiltrating lymphocytes immune evasion 
MUC5AC EXPRESSION UP-REGULATION GOBLET CELL HYPERPLASIA IN THE AIRWAY OF PATIENTS WITH CHRONIC OBSTRUCTIVE PULMONARY DISEASE被引量：6
《Chinese Medical Sciences Journal》2005年第3期181-184,共4页Rui Ma Ying Wang Gang Cheng Hui-zhen Zhang Huan-ying Wan Shao-guang Huang 
Supportedby ShanghaiNaturalScienceFund (02ZB14040 ).
Objective To determine the number of goblet cells, the change of MUC5AC expression in chronic obstructive pul- monary disease (COPD) patients and the relationship of smoking with goblet cell, MUC5AC, and lung function...
关键词：chronic obstructive pulmonary disease goblet cell MUC5AC 
Up-Regulation of CCR5 and CXCR4 Expression on Human Monocytes by Interferon Gamma
《Tsinghua Science and Technology》2003年第4期440-444,共5页陆韵 刘祖强 陈应华 
Supported by the National Key Basic Research Specific Funds (No. G19990 75 6 0 7) and the National ScienceFoundation for Outstanding Young Scientist of China(No. 30 0 2 5 0 38)
Chemokine receptors, mainly CCR5 and CXCR4, have been proved to be the important coreceptors in HIV 1 entry. HIV 1 disease progression is, in general, characterized by an initial predominance of CCR5 using macrop...
关键词：HIV  1 IFN  γ chemokine receptor CXCR4 CCR5 
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