ENDOLYSIN

作品数：7被引量：30H指数：1
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相关领域：农业科学生物学更多>>
相关作者：崔百明杨林郑银英阮丽芳秦彤更多>>
相关机构：吉林大学石河子大学中国农业科学院华中农业大学更多>>
相关期刊：《Journal of Animal Science and Biotechnology》《Virologica Sinica》《World Journal of Gastrointestinal Pharmacology and Therapeutics》《中国农业科学》更多>>
相关基金：国家自然科学基金国家科技重大专项更多>>
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解淀粉欧文氏菌噬菌体Kuerle的分离、基因组测定及其裂解功能分析被引量：1
《中国农业科学》2024年第2期295-305,共11页陈妞 余成敏 崔百明 任彩霞 杨丽颖 董钰 刘琳 郑银英 
兵团科技攻关计划(2023AB004-03)。
【背景】解淀粉欧文氏菌(Erwiniaamylovora)是仁果类果树火疫病的病原体,对全球苹果和梨的生产构成严重威胁。随着抗生素耐药菌株的出现,火疫病的防治面临巨大的挑战。【目的】分离一种新的裂解解淀粉欧文氏菌的噬菌体,并分析该噬菌体...
关键词：解淀粉欧文氏菌 噬菌体分离 基因组分析 裂解系统 HOLIN ENDOLYSIN 
Specific inhibition of Streptococcus bovis by endolysin LyJH307 supplementation shifts the rumen microbiota and metabolic pathways related to carbohydrate metabolism被引量：1
《Journal of Animal Science and Biotechnology》2022年第1期209-223,共15页Hanbeen Kim Tansol Park Inhyuk Kwon Jakyeom Seo 
supported by the National Research Foundation of Korea(NRF)grant funded by the Korea government(MSIT)(No.2019R1F1A1056904).
Background:Endolysins,the bacteriophage-originated peptidoglycan hydrolases,are a promising replacement for antibiotics due to immediate lytic activity and no antibiotic resistance.The objectives of this study were to...
关键词：ENDOLYSIN Rumen microbiota Ruminal acidosis Streptococcus bovis 
The bacteriophage mu lysis system–A new mechanism of host lysis?
《BIOCELL》2021年第5期1175-1186,共12页SAIKAT SAMANTA ASHISH RANJAN SHARMA ABINIT SAHA MANOJ KUMAR SINGH ARPITA DAS MANOJIT BHATTACHARYA RUDRA PRASAD SAHA SANG-SOO LEE CHIRANJIB CHAKRABORTY 
Hallym University Research Fund and by Basic Science Research Program through the National Research Foundation of Korea(NRF)Funded by the Ministry of Education(NRF-2020R1C1C1008694&NRF-2020R1I1A3074575).
Bacteriophages are viruses that infect bacteria and can choose any one of the two alternative pathways for infection,i.e.,lysis or lysogeny.Phage lysis is one of the conventional biological processes required to sprea...
关键词：Bacteriophage Mu Host cell lysis ENDOLYSIN HOLIN Spanin 
Phage therapy: An alternative to antibiotics in the age of multi-drug resistance被引量：28
《World Journal of Gastrointestinal Pharmacology and Therapeutics》2017年第3期162-173,共12页Derek M Lin Britt Koskella Henry C Lin 
Supported by Winkler Bacterial Overgrowth Research Fund(in part)
The practice of phage therapy, which uses bacterial viruses(phages) to treat bacterial infections, has been around for almost a century. The universal decline in the effectiveness of antibiotics has generated renewed ...
关键词：BACTERIOPHAGE Bacteriophage therapy PHAGE Phage therapy ENDOLYSIN LYSIN Multidrug resistance Antibiotic resistance Phage safety Methicillin-resistant S. aureus 
Structural and biochemical characterization of the staphylococcal phage endolysin LysGH15
《Science Foundation in China》2015年第2期10-10,共1页
With the support by the National Natural Science Foundation of China,Prof.Han Wenyu’s laboratory at the College of Veterinary Medicine,Jilin University,reported the structural and biochemical characterization of stap...
关键词：STAPHYLOCOCCAL PHAGE BIOCHEMICAL METHICILLIN Jilin groove LYSIN inactive residues guided 
Multiple-site mutations of phage Bp7 endolysin improves its activities against target bacteria
《Virologica Sinica》2015年第5期386-395,共10页Can Zhang Yuanchao Wang Huzhi Sun Huiying Ren 
provided by the Natural Science Foundation of Shandong Province,China (ZR2015CM020 and ZR2013 CQ024)
The widespread use of antibiotics has caused serious drug resistance. Bacteria that were once easily treatable are now extremely difficult to treat. Endolysin can be used as an alternative to antibiotics for the treat...
关键词：BACTERIOPHAGE Bp7 endolysin(Bp7e) Bp7 ENDOLYSIN MU 
电转染法制备奶牛转溶葡球菌酶(Lysostaphin)和内溶素(Endolysin)基因胚胎
《农业生物技术学报》2013年第2期206-215,共10页杨林 杜卫华 郝海生 刘岩 秦彤 赵学明 王栋 朱化彬 王宗礼 
国家转基因生物新品种培育科技重大专项(No.2009ZX08010-015B)和(No.2009ZX08011-031B)
溶葡球菌酶(Lysostaphin)是一种含锌的单链蛋白酶,能有效地杀灭金黄色葡萄球菌。内溶素(Endolysin)是双链DNA噬菌体所特有,是一类胞壁质水解酶,具有广泛的抗菌效果。内溶素与抗生素之间有高效的协同作用。本研究通过BTX电转染和AMAXA核...
关键词：溶葡萄球菌酶 内溶素 电转染 转基因 乳房炎 
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