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supported by the National Key Research and Development Program of China(No.2018YFA0703200);the National Natural Science Foundation of China(Nos.21975176,52121002);the Seed Foundation of Tianjin University,China(No.2024XJD-0058);the Fund of the Haihe Laboratory of Sustainable Chemical Transformations,China.
Amide and imide groups have been widely used in the design of organic semiconductors,and the development of new structure semiconductors based on these functional groups is of great interest to further improve the per...
the National Natural Science Foundation of China (No. 21772134);the Fundamental Research Funds for the Central Universities (No. 20826041D4117)。
Naphthyridine-fused bisimidazolium salts were designed and synthesized for the first time. The study of the Cu(Ⅱ) and Pd(Ⅱ) complexes demonstrated that the deprotonated dicarbene ligands are rigid chelating C,C-liga...
supported by the Natural Science Foundation of Hunan Province(No.2018JJ3196);the opening project of key laboratory of comprehensive utilization of advantage plants resources in Hunan south,Hunan university of science and engineering(No.XNZW17C04,XNZW17C05);aid program for science and technology innovative research team in higher educational institutions of Hunan province(No.2012-318)
The title compound(14 S)-2,14-diphenyl-6,6 a,11,12-tetrahydro-5 H,10 H,14 H-[1,8] naphthyridino[1,2-c]pyrido[3,2,1-ij]quinazoline-3-carbonitrile(C31 H26 N4, Mr = 454.56) has been synthesized with 2-aminonicotinald...
financial supported by National Natural Science Foundation of China(Nos.21372079,21472046);Shanghai Pujiang Program(No.14PJD012)
1,8-Naphthyridines(NAP) are biological important scaffolds in bioactive molecules design. By hybrid of NAP with neonicotinoid core structure, nine novel NAP derivatives were synthesized and subjected to insecticidal...
supported by the Natural Science Foundation of Shaanxi Province(No.2013JM2005);the National Science Council of China and the Full-Time Master Innovation Fund of Xi’an Shiyou University(No.2015cx140735)
Molecular structure of a naphthyridine and pyrazine amine ligand, N2,N7-di(pyrazin-2-yl)-1,8-naphthyri-dine-2,7-diamine(H2dpznda 1) was studied, and a three-dimensional supramolecular network with a double helix c...
supported by the National Natural Science Foundation of China(Nos.81473098 and 81473099);Hebei Provincial Key Research Project of Medical Science(Nos.ZD20140027 and 20150588)
The apical sodium-dependent bile acid transporter(ASBT) is the main transporter to promote re-absorption of bile acids from the intestinal tract into the enterohepatic circulation.Inhibition of ASBT could increase the...
An efficient method for the synthesis of novel benzo[b]pyrimido[4′,5′:5,4]thieno[2,3e]-[1,6]naphthyridine-8-one derivatives via Pictet-Spengler cyclization is reported. The reaction of 4-(3-aminopyrimido[4,5-d]thi...
An efficient method for the synthesis of novel benzo[b]pyrido[3',2':4,5]thieno[2,3-e][l,6]naphthyridine-8-one derivatives has been developed using a Pictet-Spengler reaction between 4-(3-aminothieno[2,3-b]pyridin-...
financial support from the Science and Technology Department of Liaoning Province(No.2011220022)
An efficient method for the synthesis of benzo[b]benzofurano[2,3-e][1,6]naphthyridine-8-one derivatives has been developed via Pictet-Spengler reaction of 4-(3-aminobenzofuran-2-yl)quinoline-2-ones,which could be ob...
support provided by the National Natural Science Foundation of China(Nos.20872028 and 21072045)
Novel tricyclic fluoroquinolones,[1,2,4]triazolo[3,4-h][1,8]naphthyridine-8-one-7-carboxylic acid derivatives 4a-4h bearing carrying a functional Mannich-base moiety at the C-8 position,were synthesized and evaluated ...