MACROLACTAMIZATION

作品数：4被引量：5H指数：1
导出分析报告
相关领域：理学更多>>
相关期刊：《Chinese Journal of Chemistry》《Science China Chemistry》《Chinese Chemical Letters》更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划更多>>
-
在结果中检索

检索结果分析

结果分析中...
共 条 记 录，以下是1-4
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Rh(Ⅲ)-catalyzed late-stage C-H alkenylation and macrolactamization for the synthesis of cyclic peptides with unique Trp(C7)-alkene crosslinks
《Chinese Chemical Letters》2024年第8期270-277,共8页Shulei Hu Yu Zhang Xiong Xie Luhan Li Kaixian Chen Hong Liu Jiang Wang 
the National Key R&D Program of China(No.2022YFA1302900 to H.Liu);National Natural Science Foundation of China(Nos.82130105,22337003,82121005 to H.Liu;and Nos.22177124,82322063 to J.Wang);Program of Shang-hai Academic Research Leader(No.23XD1460300 to J.Wang);the Lingang Laboratory(No.LG-GG-202204-02 to J.Wang)for supporting this work.We would like to acknowledge Shanghai Highline Therapeutics.
Heterocycle-braced cyclic peptides have demonstrated enhanced metabolic stability,increased potency and selectivity.Here,we present a rapid synthesis method for constructing Trp(C7)-alkene(E)-crosslinked cyclic peptid...
关键词：C-H functionalization Rh(Ⅲ)-catalyzed ALKENYLATION Cyclic peptides MACROLACTAMIZATION 
Asymmetric synthesis of emericellamide B
《Chinese Chemical Letters》2015年第10期1209-1215,共7页Rong-Guo Ren Jing-Yi Ma Zhuo-Ya Mao Yi-Wen Liu Bang-Guo Wei 
the National Natural Science Foundation of China (Nos. 21472022, 21272041, 21072034);Key Laboratory for Chemical Biology of Fujian Province for financial support
Asymmetric total synthesis of emericellamide B（9.4%, 17 longest linear steps） is detailed in this report. In this synthetic route, the highly methylated（2R,3R,4S,6S）-3-hydroxy-2,4,6-trimethyldodecanoic acid（HTMD...
关键词：Cyclic depsipeptide Antifungal agents Emericellamide Total synthesis Macrolactamization 
Chemical synthesis of a cyclotide via intramolecular cyclization of peptide O-esters被引量：5
《Science China Chemistry》2012年第1期64-69,共6页ZHENG Ji-Shen CHANG Hao-Nan SHI Jing LIU Lei 
supported by the National Natural Science Foundation of China(20932006,91013007);the National Basic Research Program of China(973 Program)(2011CB965300)
Cyclotides constitute a fascinating family of circular proteins containing ca.30 amino acid residues.They have a unique cyclic cysteine knot topology and exhibit remarkable thermal,chemical and enzymatic stabilities.T...
关键词：CYCLOTIDES chemical synthesis peptide O-ester native chemical ligation MACROLACTAMIZATION 
A novel synthetic use of 2-bromo- 1-methylpyridinium iodide for macrolactamization
《Chinese Journal of Chemistry》1994年第2期158-168,共11页BAI, Dong-Lu BO, Yun-Xin ZHOU, Qi-Ting Shanghai Institute of Materia Medica, Chinese Academy of Sciences, Shanghai 200031, China 
Project supported by the National Natural Science Foundation of China.
Using 2-bromo-1-methylpyridimium iodide as carboxyl activating agent, 10 ansa-macrolactams were prepared conveniently from the corresponding seco-precursor w-aminoacids in the yields of 78-2%.
关键词：LACTAM ansa-macrolactam CYCLIZATION lactamization. 
全选清除导出
共1页<1>
检索报告 对象比较 聚类工具 使用帮助 返回顶部