PRION

作品数：173被引量：154H指数：5
导出分析报告
相关领域：医药卫生生物学更多>>
相关作者：朱钦士赵德明周筠梅练富林柯莎更多>>
相关机构：中国农业大学中国科学院南加州大学厦门大学更多>>
相关期刊：更多>>
相关基金：国家自然科学基金国家重点基础研究发展计划国家高技术研究发展计划中国科学院知识创新工程重要方向项目更多>>
-
在结果中检索

检索结果分析

结果分析中...
选择条件：
  • 期刊=Science China（Life Sciences）x
共 条 记 录，以下是1-3
全选清除导出
参考文献引证文献引用追踪
视图：
排序：
Progress in the development of therapeutic antibodies targeting prion proteins and β-amyloid peptides被引量：1
《Science China(Life Sciences)》2010年第8期959-963,共5页HE JinSheng1, ZHANG Ying1 & HONG Tao1,2 1College of Life Sciences and Bioengineering, School of Science, Beijing Jiaotong University, Beijing 100044, China 2Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing 100052, China 
supported by the National High Technology Research and Development Program of China (Grant No. 2006AA02A247);the Scientific and Technological Major Special Project of China (Grant No. 2009ZX10004-216)
Prion diseases and Alzheimer’s disease (AD) are characterized by protein misfolding, and can lead to dementia. However, prion diseases are infectious and transmissible, while AD is not. The similarities and differenc...
关键词：PRION Alzheimer’s disease IMMUNOTHERAPY ANTIBODY CONFORMATION 
Establishment of bovine prion peptide-based monoclonal antibodies for identifying bovine prion被引量：3
《Science China(Life Sciences)》2009年第8期754-760,共7页ZHAO Li1,HOU XinSheng5,JI Rong2,HAN ChunHui2,YU XiuPing3,HONG Tao4,5 1 Department of Laboratory Science of Microbiology,School of Public Health,Shandong University,Jinan 250012,China 2 Institute of Nutrition and Food Safety,Chinese Center of Disease Prevention and Control,Beijing 100021,China 3 Department of Microbiology,School of Medicine,Shandong University,Jinan 250012,China 4 Institute of Virus Disease Prevention and Control,Chinese Center for Disease Control and Prevention,Beijing 100052,China 5 Institute of Biological Science and Technology,School of Science,Beijing Jiaotong University,Beijing 100044,China 
To obtain high titer monoclonal antibodies(McAbs) which can react with mammalian prion protein(PrP),Balb/C mice were immunized with bovine(Bo) PrP peptide(BoPrP 209-228 aa) coupled to keyhole limpet hemocyanin(KLH).Th...
关键词：PRION MONOCLONAL antibody Western BLOT IMMUNOHISTOCHEMISTRY ELISA 
PrP mutants with different numbers of octarepeat sequences are more susceptible to the oxidative stress被引量：4
《Science China(Life Sciences)》2008年第7期630-639,共10页AN Run1 ,2,DONG ChenFang 2,LEI YanJun 1,2,HAN Lu 2,LI Ping 2,CHEN JianMing 2,WANG GuiRong 2, SHI Qi 2 ,GAO Chen 2 ,JIANG HuiYing 2 ,ZHOU Wei 2 ,HAN Jun 2 ,CHU YongLie 1 ,DONG XiaoPing 2 1School of Medicine,Xi’an JiaoTong University,Xi’an 710061,China 2State Key Laboratory for Infectious Disease Prevention and Control,National Institute for Viral Disease Control and Prevention, Chinese Center for Disease Control and Prevention,YingXin Rd 100,Beijing 100052,China 
the National Science and Technology Task Force Project(Grant No.2006BAD06A13-2);National Basic Research Program(973 Program)of China(Grant No.2007CB310505);National Natural Science Foundation of China(Grant Nos.30571672,30500018 and 30771914)
One of the physiological functions of cellular prion protein(PrP C )is believed to work as a cellular resistance to oxidative stress,in which the octarepeats region within PrP plays an important role.However,the detai...
关键词：PRION protein oxidative stress GLUTATHIONE PEROXIDASE reactive oxygen species cell VIABILITY 
全选清除导出
共1页<1>
检索报告 对象比较 聚类工具 使用帮助 返回顶部