supported by the Ministry of Science and Technology of China(2017YFA0506300 to N.M.;2019YFA0508403 to P.L.);the National Natural Science Foundation of China(31771536,31860316).
Biomolecular condensation driven by liquid-liquid phase separation(LLPS)is key to assembly of membraneless organelles in numerous crucial pathways.It is largely unknown how cellular structures or components spatiotemp...
This work was supported by the National Key Research and Development Program of China(Grant number 2016YFD0500502);the National Basic Research Program of China(Grant number 2014CB138502);the Priority Academic Program Development of Jiangsu Higher Education Institutions;and the Jiangsu Collaborative Innovation Center of Meat Production and Processing,Quality and Safety Control.
Background:Transzonal projections(TZPs)constitute a structural basis for the communication between the oocyte and its surrounding cumulus cells(CCs),which play critical roles in promoting the oocyte maturation.Previou...
the National Natural Science Foundation of China (31570726 and 31170694);the National Basic Research Program (2014CB910700).
The presence and functions of nuclear actin have been controversial due to the lack of molecular mechanisms.Nuclear actin and actin?『elated proteins (Arps) are subunits of several chromatin remodelers, including the ...
This work was supported by the China Ministry of Science and Technology Key New Drug Creation and Manufacturing Program (No 2014ZX9102001002 to Qiang YU), the China National Key Basic Research Program (No 2013CB9i0900 to Qiang YU), and the National Natural Science Foundation of China (No 81373447 and 81673465 to Qiang YU).
STAT1 and STAT3 are two important members of the STAT (signal transducers and activators of transcription) protein family and play opposing roles in regulating cancer cell growth. Suppressing STAT3 and/or enhancing ...
This work was supported by grants from the Ministry of Science and Technology of China (2013CB945100) and the National Natural Science Foundation of China (31671390 and 31471266). X.Q. was supported by post-doctoral fellowships from Tsinghua-Peking Joint Center for Life Sciences and the China Postdoctoral Science Foundation (grant no. 2015M571028).
Polarized tip growth is a fundamental cellular process in many eukaryotes. In this study, we examined the dynamic restructuring of the actin cytoskeleton and its relationship to vesicle transport during pollen tip gro...
supported by grants from the National Natural Science Foundation of China (31125004 and 31071179);the Ministry of Science and Technology of China (2013CB945100 and 2011CB944600)
Regulation of actin dynamics is a central theme in cell biology that is important for different aspects of cell physiology. Villin, a member of the villin/gelsolin/fragmin superfamily of proteins, is an important regu...