N-MYRISTOYLATION

作品数：4被引量：16H指数：3
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相关期刊：《Cellular & Molecular Immunology》《Acta Pharmacologica Sinica》《Signal Transduction and Targeted Therapy》《Protein & Cell》更多>>
相关基金：国家自然科学基金北京市自然科学基金国家重点基础研究发展计划更多>>
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Blockade of NMT1 enzymatic activity inhibits N-myristoylation of VILIP3 protein and suppresses liver cancer progression被引量：5
《Signal Transduction and Targeted Therapy》2023年第2期716-729,共14页Xiang-Peng Tan Yan He Jing Yang Xian Wei You-Long Fan Guo-Geng Zhang Yi-Dong Zhu Zheng-Qiu Li Hua-Xin Liao Da-Jiang Qin Xin-Yuan Guan Bin Li 
This work was supported by National Natural Science Foundation of China(82273141,31961160727,81973339);National Key Research and Development Program of China(2021YFC2501000);Key Laboratory of Guangdong Higher Education Institutes(2021KSYS009).
Hepatocellular carcinoma(HCC)is one of the most common malignant tumors.Identification of the underlying mechanism of HCC progression and exploration of new therapeutic drugs are urgently needed.Here,a compound librar...
关键词：drugs VILI ALLERGIC 
Protein N-myristoylation:functions and mechanisms in control of innate immunity被引量：5
《Cellular & Molecular Immunology》2021年第4期878-888,共11页Bin Wang Tong Dai Wenhuan Sun Yujun Wei Jiang Ren Long Zhang Mengdi Zhang Fangfang Zhou 
supported by a special program from the Ministry o f Science and Technology of China(2016YFA0502500 to L.Z.);the Chinese National Natural Science Funds(U20A20393,82041009,31925013,31671457,and 91753139 to LZ.,31871405 and 31571460 to FZ.);Jiangsu National Science Foundation(BK20180043 and 19KJA550003 to F.Z.);the Zhejiang Natural Science Fund(LD19C070001 to L.Z.);the Key Project of University Natural Science Foundation of Jiangsu Province(19KJA550003);a project funded by the Priority Academic Program Development of Jiangsu Higher Education Institutions.
Protein N-myristoylation is an important fatty acylation catalyzed by N-myristoyltransferases(NMTs),which are ubiquitous enzymes in eukaryotes.Specifically,attachment of a myristoyl group is vital for proteins partici...
关键词：N-MYRISTOYLATION Innate immunity Myristoyl switches INFECTION TLR4 Viral assembly 
N-myristoylation:from cell biology to translational medicine被引量：7
《Acta Pharmacologica Sinica》2020年第8期1005-1015,共11页Meng Yuan Zi-han Song Mei-dan Ying Hong Zhu Qiao-jun He Bo Yang Ji Cao 
the National Natural Science Foundation of China(81872885 to J.C.);Zhejiang Provincial Natural Science Foundation(Y18H310005 to J.C.);the Talent Project of Zhejiang Association for Science and Technology(No.2018YCGC002 to J.C.).
Various lipids and lipid metabolites are bound to and modify the proteins in eukaryotic cells,which are known as'protein lipidation'.There are four major types of the protein lipidation,i.e.myristoylation,palmitoylati...
关键词：N-MYRISTOYLATION N-MYRISTOYLTRANSFERASE infectious diseases parasitic diseases cancers translational medicine 
HID-1 is a peripheral membrane protein primarily associated with the medial-and transGolgi apparatus被引量：2
《Protein & Cell》2011年第1期74-85,共12页Lifen Wang Yi Zhan Eli Song Yong Yu Yaming Jiu Wen Du Jingze Lu Pingsheng Liu Pingyong Xu Tao Xu 
the National Science Foundation of China(Grant Nos.30870564,and 30900268),The Beijing Natural Science Foundation(No.5092017);the Major State Basic Research Program of China(No.2010CB833701);the CAS Project(KSCX2-SW-224 and Novo Nordisk-CAS to P Xu).
Caenorhabditis elegans hid-1 gene was first identified in a screen for mutants with a high-temperature-induced dauer formation(Hid)phenotype.Despite the fact that the hid-1 gene encodes a novel protein(HID-1)which is ...
关键词：HID-1 GOLGI peripheral membrane protein fluorescent recovery after photobleaching N-MYRISTOYLATION 
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