supported by the National Basic Research Program of China (973 Program) (2012CB518502);the National Natural Science Foundation of China (81102630);the Shanghai Leading Academic Discipline Project (S30304,B112);the Science Foundation of Shanghai Municipal Commission of Science and Technology (09DZ1976600,09dZ1974303,10DZ1975800);the Fudan Science Foundation for Young (09FQ07)
Mechanosensitive(MS) ion channels play an important role in various physiological processes.Although the determination of the structure of mechanosensitive channel of large conductance(MscL) makes the simulation s...