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作品数：543被引量：2618H指数：24
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相关领域：医药卫生农业科学更多>>
相关作者：陈四方王占祥王林郭淑芹曹艳霞更多>>
相关机构：北京大学厦门大学中国人民解放军总医院第一附属医院南方医科大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金国家科技支撑计划更多>>
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Preoperative prediction of textbook outcome in intrahepatic cholangiocarcinoma by interpretable machine learning: A multicenter cohort study
《World Journal of Gastroenterology》2025年第11期33-45,共13页Ting-Feng Huang Cong Luo Luo-Bin Guo Hong-Zhi Liu Jiang-Tao Li Qi-Zhu Lin Rui-Lin Fan Wei-Ping Zhou Jing-Dong Li Ke-Can Lin Shi-Chuan Tang Yong-Yi Zeng 
Supported by National Key Research and Development Program,No.2022YFC2407304;Major Research Project for Middle-Aged and Young Scientists of Fujian Provincial Health Commission,No.2021ZQNZD013;The National Natural Science Foundation of China,No.62275050;Fujian Province Science and Technology Innovation Joint Fund Project,No.2019Y9108;Major Science and Technology Projects of Fujian Province,No.2021YZ036017.
BACKGROUND To investigate the preoperative factors influencing textbook outcomes(TO)in Intrahepatic cholangiocarcinoma(ICC)patients and evaluate the feasibility of an interpretable machine learning model for preoperat...
关键词：Intrahepatic cholangiocarcinoma Textbook outcome Interpretable machine learning PREDICTION PROGNOSIS 
Optimal timing of endoscopic biliary drainage for bile duct leaks:A multicenter,retrospective,clinical study
《World Journal of Gastrointestinal Surgery》2025年第3期139-149,共11页De-Xin Chen Kai-Xuan Fang Sheng-Xin Chen Sen-Lin Hou Gui-Hai Wen Hai-Kun Yang Da-Peng Shi Qing-Xin Lu Ya-Qi Zhai Ming-Yang Li 
Supported by the National Key Research and Development Program,China,No.2022YFC2503603.
BACKGROUND Bile duct leaks(BDLs)are serious postsurgical adverse events.Typically,conservative management with ab-dominal drainage is the initial treatment option.However,prolonged abdominal drainage without improveme...
关键词：Endoscopic retrograde cholangiopancreatography Bile duct leaks Endoscopic nasobiliary drainage Endoscopic biliary stent drainage Optimal timing Biliary stricture 
Safety and efficacy of selective RIPK1 inhibitor SIR1-365 in hospitalized patients with severe COVID-19:A multicenter,randomized,double-blind,phase 1b trial
《Journal of Intensive Medicine》2025年第1期70-78,共9页Norberto Chavez-Tapia Muneeba Ahsan Sayeed Shobha Luxmi Douglas J.Kasper Fenchao Xue Yang Shen Weiliang Fan Wei Yuan Bin Du 
Background:Receptor-interacting protein kinase 1(RIPK1),a serine/threonine protein kinase,is mainly activated by pro-inflammatory cytokines and pathogens,including severe acute respiratory syndrome coronavirus 2(SARS-...
关键词：COVID-19 Phase 1b trial Receptor-interacting protein 1 RIPK1 RIPK1 inhibitor SIR1-365 
Multicenter analysis on the correlation between the anatomical characteristics of hepatic veins and hepatic venous wedge pressure
《World Journal of Gastroenterology》2025年第9期43-53,共11页Qiu-Xia Ye Ming-Ming Meng Yi-Fan Wu Cheng-Bin Dong Yu Zhang Bo-Wen Liu Yi-Fan Lv Shao-Li You Sa Lv Hui-Guo Ding Ying Han Yong-Ping Yang Bing Zhu Fu-Quan Liu 
Supported by Capital Medical University Affiliated Beijing Shijitan Hospital Talent Development Program during the 14th Five-Year Plan,No.2023 LJRCLFQ.
BACKGROUND Wedged hepatic venous pressure(WHVP)is a crucial variable for accurately assessing the hepatic venous pressure gradient(HVPG)and is vital for the diagnosis and prognostic evaluation of patients with portal ...
关键词：Wedged hepatic venous pressure Portal venous pressure Portal hypertension Collateral branches of the hepatic vein Transjugular intrahepatic portosystemic shunt 
Gut microbial characteristics of the damp-heat constitution:a population-based multicenter cross-sectional study
《Journal of Traditional Chinese Medicine》2025年第1期140-151,共12页LI Tianxing ZHU Linghui WANG Xueke TANG Jun YANG Lingling PANG Guoming LI Huang WANG Liying DONG Yang ZHAO Shipeng LI Yingshuai LI Lingru 
National Nonprofit Institute Research Grant for the Institute of Basic Theory for Chinese Medicine,China Academy of Chinese Medical Sciences:Mechanism of Regulating Phlegm-Dampness Constitution to Prevent Metabolic Diseases based on Gut Microbiota-host DNA Methylation(No.YZ-202151)。
OBJECTIVE:To investigate the difference in gut microbiota between population with damp-heat constitution(DHC)and balanced constitution(BC).METHODS:A multi-centered cross-sectional casecontrol study was conducted,which...
关键词：damp-heat constitution balanced constitution Traditional Chinese medicine constitution MICROBIOTA inflammatory PICRUSt multicenter study cross-sectional studies 
Current situation and influencing factors of palliative care practice ability among oncology nurses:A multicenter cross-sectional study
《International Journal of Nursing Sciences》2025年第1期35-41,I0002,共8页Xiaofei Nie Fanfan Lv Longti Li Jia Jia 
supported by the Philosophy and Social Science Research Youth Project of the Hubei Department of Education in 2022(22Q148).
Objectives:The study aimed to survey the current situation and explore the factors that influence the ability of palliative care practice among oncology nurses.Methods:A multicenter cross-sectional study was conducted...
关键词：ONCOLOGY Palliative care Core competence Pain assessment Influencing factors 
Effects of Hot Night Exposure on Human Semen Quality:A Multicenter Population-Based Study
《Biomedical and Environmental Sciences》2025年第2期178-193,共16页Tingting Dai Ting Xu Qiling Wang Haobo Ni Chunying Song Yushan Li Fuping Li Tianqing Meng Huiqiang Sheng Lingxi Wang Xiaoyan Cai Lina Xiao Xiaolin Yu Qinghui Zeng Pi Guo Xinzong Zhang 
funded by the Guangdong Provincial Natural Science Foundation of China(No.2022A1515011517).
Objective To explore and quantify the association of hot night exposure during the sperm development period(0–90 lag days) with semen quality.Methods A total of 6,640 male sperm donors from 6 human sperm banks in Chi...
关键词：Climate change Exposure-response relationship Hot night exposure Human semen quality Multicenter study 
Metastatic lymph node distribution and pathology correlations in upper and lower gastric cancer patients:A multicenter retrospective study
《World Journal of Gastrointestinal Oncology》2025年第2期56-66,共11页Xian-Bei Yuan Gang Sun Jun Niu Lei Dong Yi Sui Yong-Zhu Lv 
BACKGROUND Gastric cancer(GC)poses a significant threat to public health.However,the clinicopathological features and tumor biological behaviors vary among the GC patients,leading to individual variations in lymph nod...
关键词：Upper gastric cancer Lower gastric cancer Metastatic lymph nodes Prognosis Retrospective study 
Allogeneic hematopoietic stem cell transplantation could overcome the poor prognosis of DNMT3A^(mut)NPM1^(mut)FLT3-ITD^(mut)in acute myeloid leukemia:real-world multicenter analysis in China
《Frontiers of Medicine》2025年第1期90-100,共11页Wenxuan Huo Yifan Shen Jiayu Huang Yang Yang Shuang Fan Xiaosu Zhao Qi Wen Luxiang Wang Chuanhe Jiang Yang Cao Xiaodong Mo Yang Xu Xiaoxia Hu 
supported by the National Key Research and Development Program of China(Nos.2022YFC2502600 and 2022YFC2502606);the National Natural Science Foundation of China(Nos.82170206 and 82170208);CAMS Innovation Fund for Medical Sciences(Nos.2019-I2M-5-034 and 2022-I2M-C&T-B-121);Peking University People’s Hospital Research and Development Funds(No.RZ2022-02);Tongzhou District Distinguished Young Scholars(No.JCQN2023009);Shanghai Municipal Health Commission Project of Disciplines of Excellence(No.20234Z0002)。
The cooccurrence of NPM1,FLT3-ITD,and DNMT3A mutations(i.e.,triple mutation)is related to dismal prognosis in patients with acute myeloid leukemia(AML)receiving chemotherapy alone.In this multicenter retrospective coh...
关键词：allogeneic hematopoietic stem cell transplantation acute myeloid leukemia DNMT3A mutation NPMI mutation FLT3-ITD mutation triple mutation 
Perspectives of high-risk pregnant women on home care program in high-risk pregnancies: A multicenter, qualitative study
《Asian pacific Journal of Reproduction》2025年第1期13-20,共8页Masoumeh Sayahi Shahrbanoo Salehin Mehrnoosh Zakerkish Afsaneh Keramat Shahrbanoo Goli 
Objective:To explore the perspectives of high-risk pregnant women regarding the home care program for high-risk pregnancies.Methods:This qualitative study was conducted in a university hospital and 5 comprehensive hea...
关键词：High-risk pregnancy Home care PROGRAM Qualitative study 
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