MULTICENTER

作品数：550被引量：2648H指数：24
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相关领域：医药卫生农业科学更多>>
相关作者：陈四方王占祥王林郭淑芹曹艳霞更多>>
相关机构：北京大学厦门大学中国人民解放军总医院第一附属医院南方医科大学更多>>
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相关基金：国家自然科学基金国家重点基础研究发展计划广东省自然科学基金国家科技支撑计划更多>>
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Environmental mineral density and thyroid malignancy:A multicenter cross-sectional study
《World Journal of Experimental Medicine》2025年第2期109-120,共12页John Bukasa-Kakamba Ayrton I Bangolo Shruti Wadhwani Pascal Bayauli Nikita Wadhwani Vignesh K Nagesh Maria J Mou Princejeet S Chahal Branly Mbunga Sindhuja Chindam Taieba Mushfiq Abhishek Thapa Nidhi L Rao Isis Kapinga Kalambayi Rahul Y Rajesh Ipek B Sarioguz Vishal KR Thoomkuntla Shamsul Arefin Navneet Kaur Manasse Bukasa Mutombo Satyajeet Singh Natalia Muto Surya Vamsi Pujita Mallampalli Aliocha Natuhoyila Nkodila Simcha Weissman Jean-RenéM'Buyamba-Kabangu 
BACKGROUND Several trace minerals have been shown to be associated with thyroid cancer.Democratic Republic of Congo(DRC)is deemed the most mineral-rich country globally.Data on the characteristics of thyroid nodules i...
关键词：THYROID Cancer NODULES MINERALS Heavy metals 
Machine learning-based reconstruction of prognostic staging for gastric cancer patients with different differentiation grades:A multicenter retrospective study
《World Journal of Gastroenterology》2025年第13期48-61,共14页Yong-Le Zhang Hai-Bin Song Ying-Wei Xue 
Supported by Nn10 Program of Harbin Medical University Cancer Hospital,No.Nn10 PY 2017-03.
BACKGROUND The prognosis of gastric cancer(GC)patients is poor,and an accurate prognostic staging system would help assess patients'prognostic status before treatment and determine appropriate treatment strategies.AIM...
关键词：Gastric cancer Machine learning Positive lymph nodes ratio Prognostic staging system Tumor differentiation 
Preoperative prediction of textbook outcome in intrahepatic cholangiocarcinoma by interpretable machine learning: A multicenter cohort study
《World Journal of Gastroenterology》2025年第11期33-45,共13页Ting-Feng Huang Cong Luo Luo-Bin Guo Hong-Zhi Liu Jiang-Tao Li Qi-Zhu Lin Rui-Lin Fan Wei-Ping Zhou Jing-Dong Li Ke-Can Lin Shi-Chuan Tang Yong-Yi Zeng 
Supported by National Key Research and Development Program,No.2022YFC2407304;Major Research Project for Middle-Aged and Young Scientists of Fujian Provincial Health Commission,No.2021ZQNZD013;The National Natural Science Foundation of China,No.62275050;Fujian Province Science and Technology Innovation Joint Fund Project,No.2019Y9108;Major Science and Technology Projects of Fujian Province,No.2021YZ036017.
BACKGROUND To investigate the preoperative factors influencing textbook outcomes(TO)in Intrahepatic cholangiocarcinoma(ICC)patients and evaluate the feasibility of an interpretable machine learning model for preoperat...
关键词：Intrahepatic cholangiocarcinoma Textbook outcome Interpretable machine learning PREDICTION PROGNOSIS 
Antibiotic resistance of Helicobacter pylori and related risk factors in Hunan Province:A multicenter study
《World Journal of Gastroenterology》2025年第12期62-70,共9页Jie Xie Ming-Lin Zhang Min Guo Jian-Guo Li Yuan Liu Hong-Hui Chen Fen Wang 
Supported by the National Natural Science Foundation of China,No.82270594;the Independent Exploration and Innovation Project of Central South University,No.2024ZZTS0966.
BACKGROUND Antibiotic resistance is a key factor influencing the treatment outcomes of Helicobacter pylori(H.pylori)infection.The antibiotic resistance spectrum of H.pylori varies in different regions.We investigated ...
关键词：Helicobacter pylori Antibiotic resistance Stomach disease Resistance risk MULTICENTER 
Trends in dual antiplatelet therapy regimens and clinical outcomes among patients with acute coronary syndrome undergoing percutaneous coronary intervention with drug-eluting stents: A multicenter real-world study
《Chronic Diseases and Translational Medicine》2025年第1期57-68,共12页Preyanate Wilairat Arintaya Phrommintikul Thanyalak Chotayaporn Supharat Wattanasombat Rungtiwa Hmuenpha Supitchaya Kornjirakasemsan Duangkamon Poolpun Voratima Yoodee 
The Ajarn Kasem Pangsriwong Foundation supported the research project;Pharmaceutical Care Training Center(PCTC)at the Faculty of Pharmacy,Chiang Mai University。
Background:The patterns of dual antiplatelet therapy(DAPT)use and the associated clinical outcomes in current practice remain limited.This study evaluates DAPT regimen patterns and clinical outcomes among acute corona...
关键词：acute coronary syndrome CLOPIDOGREL dual antiplatelet therapy percutaneous coronary intervention PRASUGREL prescription pattern ticagrelor 
Optimal timing of endoscopic biliary drainage for bile duct leaks:A multicenter,retrospective,clinical study
《World Journal of Gastrointestinal Surgery》2025年第3期139-149,共11页De-Xin Chen Kai-Xuan Fang Sheng-Xin Chen Sen-Lin Hou Gui-Hai Wen Hai-Kun Yang Da-Peng Shi Qing-Xin Lu Ya-Qi Zhai Ming-Yang Li 
Supported by the National Key Research and Development Program,China,No.2022YFC2503603.
BACKGROUND Bile duct leaks(BDLs)are serious postsurgical adverse events.Typically,conservative management with ab-dominal drainage is the initial treatment option.However,prolonged abdominal drainage without improveme...
关键词：Endoscopic retrograde cholangiopancreatography Bile duct leaks Endoscopic nasobiliary drainage Endoscopic biliary stent drainage Optimal timing Biliary stricture 
Metabolic Dysfunction-Associated Steatohepatitis Detected by Neutrophilic Crown-Like Structures in Morbidly Obese Patients:A Multicenter and Clinicopathological Study
《Research》2025年第1期320-332,共13页Mengqi Fan Erfei Song Yuying Zhang Pengfei Zhang Bing Huang Kaixuan Yan Wah Yang Subrata Chakrabarti Hema Mahajan Sen Yan Ying Xu Shuang Hua Wei Liu Cunchuan Wang Aimin Xu Dewei Ye 
financially supported by NSFC(82374171 and 81570701);the Natural Science Foundation of Guangdong Province(2024A1515012945);the Key Laboratory of Model Animal Phenotyping and Basic Research in Metabolic Diseases(2018KSYS003).
Metabolic dysfunction-associated steatohepatitis(MASH)is the progressive form of metabolic dysfunction-associated steatotic liver disease(MASLD),and closely associated with a high risk of liver-related morbidity and m...
关键词：hepatic neutrophils enhanced neutrophil infiltration neutrophilic crown structures morbidly obese clinicopathological study bariatric surgery 
Safety and efficacy of selective RIPK1 inhibitor SIR1-365 in hospitalized patients with severe COVID-19:A multicenter,randomized,double-blind,phase 1b trial
《Journal of Intensive Medicine》2025年第1期70-78,共9页Norberto Chavez-Tapia Muneeba Ahsan Sayeed Shobha Luxmi Douglas J.Kasper Fenchao Xue Yang Shen Weiliang Fan Wei Yuan Bin Du 
Background:Receptor-interacting protein kinase 1(RIPK1),a serine/threonine protein kinase,is mainly activated by pro-inflammatory cytokines and pathogens,including severe acute respiratory syndrome coronavirus 2(SARS-...
关键词：COVID-19 Phase 1b trial Receptor-interacting protein 1 RIPK1 RIPK1 inhibitor SIR1-365 
Multicenter analysis on the correlation between the anatomical characteristics of hepatic veins and hepatic venous wedge pressure
《World Journal of Gastroenterology》2025年第9期43-53,共11页Qiu-Xia Ye Ming-Ming Meng Yi-Fan Wu Cheng-Bin Dong Yu Zhang Bo-Wen Liu Yi-Fan Lv Shao-Li You Sa Lv Hui-Guo Ding Ying Han Yong-Ping Yang Bing Zhu Fu-Quan Liu 
Supported by Capital Medical University Affiliated Beijing Shijitan Hospital Talent Development Program during the 14th Five-Year Plan,No.2023 LJRCLFQ.
BACKGROUND Wedged hepatic venous pressure(WHVP)is a crucial variable for accurately assessing the hepatic venous pressure gradient(HVPG)and is vital for the diagnosis and prognostic evaluation of patients with portal ...
关键词：Wedged hepatic venous pressure Portal venous pressure Portal hypertension Collateral branches of the hepatic vein Transjugular intrahepatic portosystemic shunt 
Gut microbial characteristics of the damp-heat constitution:a population-based multicenter cross-sectional study
《Journal of Traditional Chinese Medicine》2025年第1期140-151,共12页LI Tianxing ZHU Linghui WANG Xueke TANG Jun YANG Lingling PANG Guoming LI Huang WANG Liying DONG Yang ZHAO Shipeng LI Yingshuai LI Lingru 
National Nonprofit Institute Research Grant for the Institute of Basic Theory for Chinese Medicine,China Academy of Chinese Medical Sciences:Mechanism of Regulating Phlegm-Dampness Constitution to Prevent Metabolic Diseases based on Gut Microbiota-host DNA Methylation(No.YZ-202151)。
OBJECTIVE:To investigate the difference in gut microbiota between population with damp-heat constitution(DHC)and balanced constitution(BC).METHODS:A multi-centered cross-sectional casecontrol study was conducted,which...
关键词：damp-heat constitution balanced constitution Traditional Chinese medicine constitution MICROBIOTA inflammatory PICRUSt multicenter study cross-sectional studies 
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