The complex formed by two members of the S100 calcium-binding protein family, S100A8/A9, exerts apoptosisinducing activity in various cells of different origins. Here, we present evidence that the underlying molecular...
Cells and organisms are targets of endogenous and exogenous genotoxic agents. Those hits induce different lesions of the DNA including single and double strand breaks, which in turn trigger the appropriate response. D...
Transforming growth factor-beta (TGF-β)/bone morphogenic protein (BMP) signaling is involved in the vast majority of cellular processes and is fundamentally important during the entire life of all metazoans. Dere...
Acknowledgments This work was supported by the Major State Basic Research Program of China (grant no. 2003CB 114302 to M Jiang), the National Natural Science Foundation of China (grant no. 30571122 to M Jiang), and the Youth Scientific and Technological Innovation talent Project of Jiangsu Province (grant no. BK2007575 to A Zhang).
Using pharmacological and biochemical approaches, the signaling pathways between hydrogen peroxide (H2O2), calcium (Ca^2+)-calmodulin (CAM), and nitric oxide (NO) in abscisic acid (ABA)-induced antioxidant ...
supported by the Major StateBasic Research Project (Grant No. G1999053901).
MAPK families play an important role in complex cellular programs like proliferation, differentiation, development, transformation, and apoptosis. At least three MAPI(families have been characterized: extracellular si...