INTERLEUKIN-7

作品数：8被引量：22H指数：3
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Reduced interleukin-2 receptor subunitγexpression in Crohn's disease:A potential mechanism forγδT cell deficiency
《World Journal of Gastroenterology》2025年第13期152-154,共3页Md Sadique Hussain Ajay Singh Bisht Gaurav Gupta 
Crohn’s disease(CD)is a chronic inflammatory disorder characterized by dysregulated immune responses and significant disruption of intestinal immunity.A recent case-control study by Andreu-Ballester et al revealed de...
关键词：Crohn's disease Gastrointestinal immunology Interleukin-2 receptorγsubunit(CD132) Interleukin-7/interleukin-2 signaling pathway Immune regulation Immune signaling T cell apoptosis 
Use of mesenchymal stem cell therapy in COVID-19 related strokes
《Neural Regeneration Research》2023年第9期1881-1883,共3页Mahika Rawat Chiao Ng Emaad Khan Rayyan A.Shah Suha Ashfaq Ghaith A.Bahader Zahoor A.Shah 
Co ronavirus disease 2019(COVID-19) has affected a broad demographics,eliciting a more significant effect on specific groups such as males,African Americans,and Hispanic minorities.Treatment of COVID-19 often requires...
关键词：COVID-19 CYTOKINES IMMUNOTHERAPY INTERLEUKIN-7 mesenchymal stem cells NEUROINFLAMMATION sex differences stroke 
Interleukin-7 Is Associated with Clinical and Pathological Activities in Immunoglobulin A Nephropathy and Protects the Renal Proximal Tubule Epithelium from Cellular Fibrosis被引量：1
《Current Medical Science》2021年第5期880-887,共8页Yuan-jun DENG Xue-ping LIN Xiao-qing LI Ping-fan LU Yang CAI Le-le LIU Guang-chang PEI Min HAN 
supported by grants from Huazhong University of Science and Technology Research Funds for Self-dependent Innovation(No.2017KFYXJJ101);the National Natural Science Foundation of China(No.81703058,No.81970591,and No.82000656).
Objective:Diagnosis of immunoglobulin A nephropathy(IgAN)requires the evaluation of renal biopsy specimens.However,renal biopsy is an invasive procedure and is not frequently performed for various reasons.Thus,recogni...
关键词：IgA nephropathy biomarker IL-7 cellular fibrosis 
Variants of Interleukin-7/Interleukin-7 Receptor Alpha are Associated with Both Neuromyelitis Optica and Multiple Sclerosis Among Chinese Han Population in Southeastern China被引量：4
《Chinese Medical Journal》2015年第22期3062-3068,共7页Jing-Cong Zhuang Lei Wu Mei-Zhen Qian Ping-Ping Cai Qi-Bing Liu Gui-Xian Zhao Zhen-Xin Li Zhi-Ying Wu 
w The authors sincerely thank the patients and their parents for the help and willingness to take part in this study.This work was supported by grants from National Key Clinical Specialty Discipline Construction Program and Key Clinical Specialty Discipline Construction Program of Fujian and the National Natural Science Foundation of China （No. 81125009 and No. 3091110488）.
Background： Neuromyelitis optica （NMO） and multiple sclerosis （MS） are autoimmune demyelinating diseases of the central nerve system, lnterleukin-7 （IL-7） and interleukin-7 receptor alpha （IL-7Rα） were prove...
关键词：ASSOCIATION lnterleukin-7/Interleukin-7 Receptor Alpha Multiple Sclerosis Neuromyelitis Optica Chinese Han Population 
Progress and challenges in the use of latent HIV-1 reactivating agents被引量：3
《Acta Pharmacologica Sinica》2015年第8期908-916,共9页Hong-tao SHANG Ji-wei DING Shu-ying YU Tao WU Qiu-li ZHANG Fu-jun LIANG 
Highly active antiretroviral therapy （HAART） can effectively suppress the replication of human immunodeflciency virus-1 （HIV-1） and block disease progression. However, chronic HIV-1 infection remains incurable due...
关键词：HIV infection virus latency HIV reactivating agents INTERLEUKIN-7 disulfram protein kinase C agonist histone deacetylase inhibitors DNA methyltranserase inhibitors ＂shock and kill＂ strategy CD4-positive T-lymphocytes 
Type 1 interferon-induced IL-7 maintains CD8＋ T-cell responses and homeostasis by suppressing PD-1 expression in viral hepatitis被引量：1
《Cellular & Molecular Immunology》2015年第2期213-221,共9页Lifei Hou Zuliang Jie Yuejin Liang Mayura Desai Lynn Soong Jiaren Sun 
Type 1 interferon （IFN-I） promotes antigen-presenting cell maturation and was recently shown to induce hepatic IL-7 production during infection. Herein, we further explored the underlying mechanisms used by I FN-I t...
关键词：CD8＋ T cell INTERLEUKIN-7 PD-1 type 1 interferon viral hepatitis 
Interleukin-7 Receptor Signaling Network:An Integrated Systems Perspective被引量：8
《Cellular & Molecular Immunology》2008年第2期79-89,共11页Megan J. Palmer Vinay S. Mahajan Lily C. Trajman Darrell J. Irvine Douglas A.Lauffenburger Jianzhu Chen 
Interleukin-7 （IL-7） is an essential cytokine for the development and homeostatic maintenance of T and B lymphocytes. Binding of IL-7 to its cognate receptor, the IL-7 receptor （IL-7R）, activates multiple pathways...
关键词：IL-7 receptor CYTOKINE signaling network systems biology modeling 
Association of IL-7 with disease progression in Chinese HIV-1 seropositive individuals被引量：5
《Chinese Medical Journal》2006年第4期288-293,共6页WANG Qi SHANG Hong WANG Ya-nan JIANG Yong-jun LIU Jing ZHANG Zi-ning 
This research was supported by grants from the National Science Foundation of China (No.30471548). and "fifteen" national scientific technology study scheme (No. 2004 BA719A)
Background Elevated levels of interleukin-7 （IL-7） have been correlated with CD4^＋ T cell depletion and the emergence of syncytium-inducing （SI） variants in human immunodeficiency virus type-1 （HIV-1） infection...
关键词：human immunodeficiency virus 1 acquired immunodeficiency syndrome INTERLEUKIN-7 CYTOKINES CHINESE 
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