OFFSPRING

作品数：260被引量：300H指数：6
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Maternal high-fat diet impairs offspring glucose metabolism and programs hepatic DNA methylation linked to NK cell-mediated cytotoxicity signaling pathway at weaning
《Food Science and Human Wellness》2025年第4期1576-1587,共12页Sheng Zheng Ling Zhang Shixuan Zhang Guanyu Hu Yikai Li Jia Zheng 
sponsored by National Natural Science Foundation of China(81800703);Postdoctoral Fellowship Program of China Postdoctoral Science Foundation(GZC20231088);Beijing Nova Program(Z201100006820117 and 20220484181);Beijing Municipal Natural Science Foundation(7184252);the Fundamental Research Funds for the Central Universities;the Fundamental Research Funds for the Central Universities(BMU2021MX013);Peking University Clinical Scientist Training Program(BMU2023PYJH022);Peking University Medicine Seed Fund for Interdisciplinary Research;China Endocrine and Metabolism Young Scientific Talent Research Project(2022-N-02-01);China Diabetes Young Scientific Talent Research Project;Bethune-Merck Diabetes Research Fund of Bethune Charitable Foundation。
Maternal consumption of a high-fat diet has been linked to increased risks of obesity and impaired glucose metabolism in offspring.However,the precise epigenetic mechanisms governing these intergenerational effects,pa...
关键词：Maternal high-fat diet consumption Glucose metabolism DNA methylation Natural killer cell-mediated cytotoxicity WEANING 
Early-life exposure to gestational diabetes mellitus predisposes offspring to pediatric nonalcoholic fatty liver disease
《Hepatobiliary & Pancreatic Diseases International》2025年第2期128-137,共10页Qian-Ren Zhang Yan Dong Jian-Gao Fan 
supported by grants from the National Nat-ural Science Foundation of China(82170593);National Key R&D Program of China(2021YFC2700802);Collaborative Innovation Program of Shanghai Municipal Health Commission(2020CXJQ01)。
Nonalcoholic fatty liver disease(NAFLD)has emerged as the prevailing chronic liver disease in the pediatric population due to the global obesity pandemic.Evidence shows that prenatal and postnatal exposure to maternal...
关键词：Gestational diabetes mellitus Nonalcoholic fatty liver disease Lipid metabolism Fetal development Nutrition therapy 
How does asymmetric sibling rivalry respond under environmental metal pollution?A case study of the Tree Sparrow(Passer montanus)
《Avian Research》2025年第1期74-82,共9页Jian Ding Shengnan Wang Wenzhi Yang Huijie Zhang Ni Wang Yingmei Zhang 
supported by the National Natural Science Foundation of China (No.32370508 and 32201266);the China Postdoctoral Science Foundation (No.GZC20230731)。
The imbalanced allocation of maternal resources to eggs and nestlings may significantly impact the phenotype and fitness of offspring.Moreover,anthropogenic metal pollution has been reported to exert adverse effects o...
关键词：Passer montanus Environmental metal pollution Offspring characteristics Asymmetric sibling competition 
Inability of recognizing offspring underlies parental errors in the selection of offspring
《Avian Research》2025年第1期89-95,共7页Lifang Gao Wen Zhang Wenjing Zhu Yichen Wu Ran Xu Ningning Sun Yujie Wang Biyun Jia Bo Du 
provided by the National Natural Sciences Foundation of China (Grant 32071491,31772465,31672299,31572271,and 32260128)。
Inclusive fitness theory posits that altruistic behaviors,which are directed more likely towards relatives,should be favored by natural selection.However,the prevalence of alternative parenting behaviors in offspring ...
关键词：Cross-foster Cyanopica cyanus Offspring recognition Parental care Parent-offspring association 
Stress conditions extend maternal care and delay juvenile development in crayfish
《Current Zoology》2025年第1期25-32,共8页Davinder Kaur Koushik Das Jan Kubec Milos Buric 
financially supported by the Grant Agency of the University of South Bohemia No.GAJU 027/2022/Z and 065/2022/Z;made using facilities of the large research infrastructure supported by the Ministry of Education,Youth and Sports of the Czech Republic project CENAKVA(LM2023038).
Maternal care in crayfish has been extensively studied,but little is known of its response to environmental factors.We studied the duration of maternal care and its association with the juvenile development of marbled...
关键词：COMMUNICATION development marbled crayfish Procambarus virginalis OFFSPRING red swamp crayfish Procambarus clarkii 
Development of an animal model of hypothyroxinemia during pregnancy in Wistar rats
《Animal Models and Experimental Medicine》2024年第6期926-935,共10页Wei Wei Aihua Liu Min Liu Mingfeng Li Xinghan Wu Chuan Qin Zhongyan Shan Ling Zhang 
supported by the CAMS Innovation Fund for Medical Science (2021-I2M-1-034);the National Natural Science Foundation of China (grant number:81700697).
Background:Hypothyroxinemia is a subclinical thyroid hormone deficiency in which the mother has inadequate levels of T_(4) during pregnancy.The fetus relies entirely on the mother's T_(4) hormone level for early neuro...
关键词：AUTISM hypothyroxinemia during pregnancy IMH animal model offspring development T_(4) 
Maternal sleep deprivation disrupts glutamate metabolism in offspring rats
《Zoological Research》2024年第6期1221-1231,共11页Wen-Ting He Dong-Xu Li Jin-Hua Fan Zheng-Yu Yao Yu-Peng Cun Zhi-Fang Dong 
supported by the National Natural Science Foundation of China(32371030,82071395);Natural Science Foundation of Chongqing(CSTB2024NSCQ-LZX0008);Science and Technology Research Program of Chongqing Municipal Education Commission(KJQN202300424);CQMU Program for Youth Innovation in Future Medicine(W0044)。
Maternal sleep deprivation(MSD)has emerged as a significant public health concern,yet its effects on offspring metabolism remain poorly understood.This study investigated the metabolomic implications of MSD on offspri...
关键词：Maternal sleep deprivation Glutamate metabolism Metabolomics Cognitive development OFFSPRING 
Effect of exercise during pregnancy on offspring development through ameliorating high glucose and hypoxia in gestational diabetes mellitus被引量：1
《World Journal of Diabetes》2024年第11期2203-2219,共17页Yi-Bo Tang Le-Sha Wang Yi-Hui Wu Li-Xia Zhang Lu-Yao Hu Qi Wu Meng-Lin Zhou Zhao-Xia Liang 
Supported by Key R and D Program of Zhejiang Province,No.2022C03058;Medical and Health Technology Program of Zhejiang Province,No.WKJ-ZJ-2324;and 4+X Clinical Research Project of Women's Hospital,School of Medicine,Zhejiang University,No.ZDFY2022-4XB101.
BACKGROUND Gestational diabetes mellitus(GDM)women require prenatal care to minimize short-and long-term complications.The mechanism by which exercise during pregnancy affects organ development and whether glucose tra...
关键词：Gestational diabetes mellitus EXERCISE Glucose transporter 1 Hypoxia inducible factor-1α PLACENTA OFFSPRING 
Maternal diseases and congenital anomalies of the kidney and urinary tract in offspring: a cohort study被引量：2
《World Journal of Pediatrics》2024年第11期1168-1178,共11页Qiang Ma Ya-Qi Li Qing-Tang Meng Bo Yang Hai-Tao Zhang Hua Shi Chang-You Liu Tian-Chao Xiang Na Zhao Jia Rao 
supported by the National Key Research and Development Program of China(2021YFC2701101,to RJ);the Program of Shanghai Academic/Technology Research(23141900700,to RJ).
Background Congenital anomalies of the kidneys and urinary tract(CAKUT)are the most common cause of prenatally diagnosed developmental malformation.This study aimed to assess the relationship between maternal diseases...
关键词：Congenital anomalies of the kidney and urinary tract(CAKUT) Kidney anomalies Predictive model Risk factors Urinary tract dilation(UTD) 
Leading directions and effective distance of larch offspring dispersal at the upper treeline in the Northern and Polar Urals, Russia
《Forest Ecosystems》2024年第5期603-617,共15页P.A.Moiseev V.L.Semerikov T.V.Semerikova D.S.Balakin I.B.Vorobiev S.O.Viuykhin 
supported by the Russian Center for Scientific Information under grant RFBR–21–54–12016 for the sampling and treating of collected materials;by the Russian Scientific Foundation under grant RSF-24–14-00206 for data analysis and preparation of the manuscript.
Climate has changed sufficiently over the last 150 years and forced out upper treeline advance at the most studied sites around the world.The rate of advance has been extremely variable–from tens to hundreds meters i...
关键词：Effective dispersal distance Upper treeline Parentage analysis Age estimation Terrestrial laser scanning Larix sibirica Ural mountains 
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