GASTRORETENTIVE

作品数：8被引量：19H指数：3
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相关领域：医药卫生更多>>
相关期刊：《Journal of Integrative Medicine》《Chinese Journal of Natural Medicines》《Acta Pharmacologica Sinica》《World Journal of Gastroenterology》更多>>
相关基金：国家自然科学基金更多>>
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Recent advances in alginate based gastroretentive technologies for drug delivery applications
《Medicine in Novel Technology and Devices》2023年第2期43-54,共12页Olivia Sen Sreejan Manna Gouranga Nandi Subrata Jana Sougata Jana 
The efficacy of orally delivered medicines can be maximized through enhancing the gastric residence period and modifying the drug release pattern according to therapeutic need.Several technologies were investigated th...
关键词：Gastroretentive drug delivery system ALGINATE Low density systems Mucoadhesive systems Hydrogel forming system Drug delivery applications 
Discovery and preclinical development of ⅢM-160, a Bergenia ciliatabased anti-inflammatory and anti-arthritic botanical drug candidate被引量：3
《Journal of Integrative Medicine》2019年第3期192-204,共13页Sandip B.Bharate Vikas Kumar Sonali S.Bharate Bikarma Singh Gurdarshan Singh Amarinder Singh Mehak Gupta Deepika Singh Ajay Kumar Surjeet Singh Ram A.Vishwakarma 
financially supported by CSIR 12th Five Year Plan project BSC-0205;CSIR-Phytopharmaceutical Mission Project HCP010;CSIR-YSA (Young Scientist Award,P90807) Research Grant;the fellowship from Department of Biotechnology,India (GAP-2158).IIIM publication number: ⅢM/2222/2018
Objective: Bergenia ciliata(Haw.) Sternb. is used in the Indian traditional system of medicine to treat various ailments including rheumatism and to heal wounds. The objective of the present study was to perform a pre...
关键词：BOTANICAL PRECLINICAL candidate UIM-160 Bergenia ciliata Arthritis GASTRORETENTIVE sustained release formulation BERGENIN 
Formulation development and evaluation of gastroretentive floating beads with Brucea javanica oil using ionotropic gelation technology被引量：2
《Chinese Journal of Natural Medicines》2018年第4期293-301,共9页ZHANG Yue ZHANG Xi-Tong ZHANG Qi WANG Bing ZHANG Tong 
supported by the National Natural Science Foundation of China(No.81303233);Foundation of Shanghai Science and Technology Committee(No.13401900300);Shanghai Municipal Commission of Health and Family Planning(No.20124074)
In the present study, a gastric retention floating system for Brucea javanica oil, composed of alginate and carrageenan, was prepared using ionotropic gelation. Parameters for floatability, drug load, encapsulation ef...
关键词：Brucea javanica oil SIMAROUBACEAE Alginate–carrageenan beads Gastric retention Box–Behnken design SPET/CT 
Gastroretentive drug delivery systems for the treatment of Helicobacter pylori被引量：5
《World Journal of Gastroenterology》2014年第28期9321-9329,共9页Shan Zhao Yan Lv Jian-Bin Zhang Bing Wang Guo-Jun Lv Xiao-Jun Ma 
Helicobacter pylori (H. pylori) is one of the most common pathogenic bacterial infections and is found in the stomachs of approximately half of the world’s population. It is the primary known cause of gastriti...
关键词：Helicobacter pylori Gastroretentive systems Floating systems Bioadhesive systems Expandable systems 
Development and characterization of amoxicillin loaded floating microballoons for the treatment of Helicobacter pylori induced gastric ulcer被引量：2
《Asian Journal of Pharmaceutical Sciences》2013年第3期174-180,共7页Rajendra Awasthi Giriraj T.Kulkarni 
The current communication reports in vitro characterization of the optimized hollow floating microballoons of amoxicillin on the basis of micromeritic properties and in vitro minimum inhibitory concentration(MIC).Amox...
关键词：FLOATING Gastric ulcer GASTRORETENTIVE H.PYLORI Micromeritic MICROBALLOONS 
In vitro and in vivo evaluation of gastroretentive floating drug delivery system of ofloxacin被引量：1
《Asian Journal of Pharmaceutical Sciences》2013年第3期191-198,共8页Rajani Shaky Panna Thapa Ranendra N.Saha 
This study aimed to develop hydrophilicmatrix based controlled release gastroretentive drug delivery system of ofloxacin and conducting its in vitro and in vivo evaluations.Effervescent floating gastroretentive drug d...
关键词：OFLOXACIN Gastroretentive drug delivery SYSTEM BoxeBehnken design BIOAVAILABILITY FLOATING 
Design of a gastroretentive mucoadhesive dosage form of furosemide for controlled release被引量：4
《Acta Pharmaceutica Sinica B》2012年第5期509-517,共9页Sharad S.Darandale Pradeep R.Vavia 
The aim of the present study was to develop and characterize a gastroretentive dosage form suitable for controlled drug release.It consists of a drug loaded polymeric film made up of a bilayer of immediate(IR)and cont...
关键词：Gastroretentive dosage form Controlled release FUROSEMIDE BIOADHESION Bilayer film Hydroxypropylβ-cyclodextrin CARBOPOL 
Novel gastroretentive sustained-release tablet of tacrolimus based on self-microemulsifying mixture： in vitro evaluation and in vivo bioavailability test被引量：3
《Acta Pharmacologica Sinica》2011年第10期1294-1302,共9页Yan-ping WANG Yong GAN Xin-xin ZHANG 
Aim： To develop a novel gastroretentive drug delivery system based on a self-microemulsifying （SME） lipid mixture for improving the oral absorption of the immunosuppressant tacrolimus. Methods： Liquid SME mixture,...
关键词：immunosuppressants TACROLIMUS BIOAVAILABILITY self-microemulsifying lipid mixture gastroretentive sustained-releasetablet 
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